A strategy to passively reduce neuroinflammation surrounding devices implanted chronically in brain tissue by manipulating device surface permeability

Biomaterials

Volumn 36, Issue , 2015, Pages 33-43

  Skousen, John L ^a   Bridge, Michael J ^a   Tresco, Patrick A ^a  

^a University of Utah   (United States)

Author keywords

Cytokine; Electrode; Finite element analysis; Foreign body response; Inflammation; Macrophage

Indexed keywords

BIOCOMPATIBILITY; BRAIN; COATINGS; DIFFUSION; ELECTRODES; FINITE ELEMENT METHOD; MACROPHAGES; TISSUE;

COMPUTATIONAL MODEL; CYTOKINES; FOREIGN BODY RESPONSE; IMMUNOHISTOCHEMISTRY; IMPLANTATION PERIODS; INFLAMMATION; PRO-INFLAMMATORY CYTOKINES; SURFACE PERMEABILITY;

DIFFUSION COATINGS;

CHLORDANE; SILICON; CYTOKINE;

ADRENAL CORTEX; ADULT; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BRAIN TISSUE; CONTROLLED STUDY; DIFFUSION; DIFFUSION SINK; FOREIGN BODY REACTION; HYDROGEL; IMMUNOCOMPETENT CELL; IMMUNOREACTIVITY; MACROPHAGE; MALE; MICROELECTRODE; MICROGLIA; MONONUCLEAR PHAGOCYTE; NERVE CELL; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PERMEABILITY; PRIORITY JOURNAL; RAT; SURFACE PROPERTY; TISSUE IMPLANT; ADVERSE EFFECTS; ANIMAL; BRAIN; FINITE ELEMENT ANALYSIS; FOREIGN-BODY REACTION; IMMUNOLOGY; PROSTHESES AND ORTHOSES; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; BRAIN; CYTOKINES; FINITE ELEMENT ANALYSIS; FOREIGN-BODY REACTION; MALE; PERMEABILITY; PROSTHESES AND IMPLANTS; RATS, SPRAGUE-DAWLEY;

EID: 84921502338     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.08.039     Document Type: Article

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