Evaluation of three different families of bombesin receptor radioantagonists for targeted imaging and therapy of gastrin releasing peptide receptor (GRP-R) positive tumors

Journal of Medicinal Chemistry

Volumn 58, Issue 2, 2015, Pages 682-691

  Mansi, Rosalba ^a,b   Abiraj, Keelara ^a   Wang, Xuejuan ^a   Tamma, Maria Luisa ^a   Gourni, Eleni ^b   Cescato, Renzo ^c   Berndt, Sandra ^d   Reubi, Jean Claude ^c   Maecke, Helmut R ^a,b  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF BERN   (Switzerland)

^d Bayer HealthCare   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BOMBESIN ANTAGONIST; GASTRIN RELEASING PEPTIDE RECEPTOR; INDIUM 111; BOMBESIN RECEPTOR; CALCIUM; INDIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CALCIUM MOBILIZATION; CANCER THERAPY; CONTROLLED STUDY; DRUG POTENCY; DRUG UPTAKE; FEMALE; HUMAN; HUMAN CELL; IC50; IMAGING; IMMUNOFLUORESCENCE; INTERNALIZATION; ISOTOPE LABELING; MOUSE; NONHUMAN; PANCREAS; POSITRON EMISSION TOMOGRAPHY; ANIMAL; ANTAGONISTS AND INHIBITORS; DIAGNOSTIC USE; FLUORESCENCE MICROSCOPY; METABOLISM; NEOPLASMS; RADIOASSAY; SCINTISCANNING; STRUCTURE ACTIVITY RELATION; TISSUE DISTRIBUTION; TUMOR CELL LINE;

ANIMALS; CALCIUM; CELL LINE, TUMOR; HUMANS; INDIUM RADIOISOTOPES; MICE; MICROSCOPY, FLUORESCENCE; NEOPLASMS; POSITRON-EMISSION TOMOGRAPHY; RADIOLIGAND ASSAY; RECEPTORS, BOMBESIN; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE DISTRIBUTION;

EID: 84921495951     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm5012066     Document Type: Article

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