Chronic morphine-induced MicroRNA-124 promotes microglial immunosuppression by modulating P65 and TRAF6

Journal of Immunology

Volumn 194, Issue 3, 2015, Pages 1021-1030

  Qiu, Shuwei ^a,b   Feng, Yimin ^b   LeSage, Gene ^b   Zhang, Ying ^c   Stuart, Charles ^b   He, Lei ^a   Li, Yi ^a   Caudle, Yi ^b   Peng, Ying ^a   Yin, Deling ^b  

^a SUN YAT SEN UNIVERSITY   (China)

^b East Tennessee State University   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MICRORNA 124; MORPHINE; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; 3' UNTRANSLATED REGION; MICRORNA; MIRN124 MICRORNA, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME REGULATION; GENE EXPRESSION; GENE FUNCTION; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; INNATE IMMUNITY; INTRACELLULAR SIGNALING; LONG TERM EXPOSURE; MALE; MICROGLIA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; TRANSCRIPTION REGULATION; UPREGULATION; 3' UNTRANSLATED REGION; ANIMAL; BASE PAIRING; BINDING SITE; CELL LINE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; NUCLEOTIDE SEQUENCE; RNA INTERFERENCE;

3' UNTRANSLATED REGIONS; ANIMALS; BASE PAIRING; BASE SEQUENCE; BINDING SITES; CELL LINE; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY, INNATE; IMMUNOMODULATION; MALE; MICE; MICROGLIA; MICRORNAS; MORPHINE; RNA INTERFERENCE; TNF RECEPTOR-ASSOCIATED FACTOR 6; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION, GENETIC;

EID: 84921470810     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400106     Document Type: Article

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