Peptide inhibitors of the Escherichia coli DsbA oxidative machinery essential for bacterial virulence

Journal of Medicinal Chemistry

Volumn 58, Issue 2, 2015, Pages 577-587

  Duprez, Wilko ^a   Premkumar, Lakshmanane ^a   Halili, Maria A ^a   Lindahl, Fredrik ^a   Reid, Robert C ^a   Fairlie, David P ^a   Martin, Jennifer L ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CYSTEINE; DSBA PROTEIN; DSBB PROTEIN; HEPTAPEPTIDE; PEPTIDE; PROTEIN INHIBITOR; THIOREDOXIN; UNCLASSIFIED DRUG; DSBA PROTEIN, E COLI; ESCHERICHIA COLI PROTEIN; PROTEIN DISULFIDE ISOMERASE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL VIRULENCE; BINDING SITE; COMPLEX FORMATION; CRYSTAL STRUCTURE; ESCHERICHIA COLI; EXPRESSION VECTOR; GRAM NEGATIVE BACTERIUM; IC50; ISOTHERMAL TITRATION CALORIMETRY; MOLECULE; NONHUMAN; OXIDATION; PROTEIN BINDING; STRUCTURE ACTIVITY RELATION; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; OXIDATION REDUCTION REACTION; PATHOGENICITY; VIRULENCE;

ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; OXIDATION-REDUCTION; PEPTIDES; PROTEIN DISULFIDE-ISOMERASES; STRUCTURE-ACTIVITY RELATIONSHIP; VIRULENCE;

EID: 84921470541     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm500955s     Document Type: Article

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