Water-mediated recognition of simple alkyl chains by heart-type fatty-acid-binding protein

Angewandte Chemie - International Edition

Volumn 54, Issue 5, 2015, Pages 1508-1511

  Matsuoka, Shigeru ^a   Sugiyama, Shigeru ^a   Matsuoka, Daisuke ^a   Hirose, Mika ^a   Lethu, Sébastien ^a   Ano, Hikaru ^a   Hara, Toshiaki ^a   Ichihara, Osamu ^b   Kimura, S Roy ^b   Murakami, Satoshi ^c   Ishida, Hanako ^a   Mizohata, Eiichi ^a   Inoue, Tsuyoshi ^a   Murata, Michio ^a  

^a OSAKA UNIVERSITY   (Japan)

^b SCHRÖDINGER INC   (United States)

^c TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Fatty acids; Molecular dynamics; Molecular evolution; Structural biology; Water clusters

Indexed keywords

BINDING ENERGY; BIOLOGY; CHAIN LENGTH; CRYSTALLOGRAPHY; CYTOLOGY; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; MOLECULES; PROTEINS; X RAY CRYSTALLOGRAPHY;

CALORIMETRIC METHODS; ENERGY PRODUCTIONS; FATTY ACID-BINDING PROTEINS; HEART-TYPE FATTY ACID; LONG CHAIN FATTY ACID; MOLECULAR EVOLUTION; STRUCTURAL BIOLOGY; WATER CLUSTER;

FATTY ACIDS;

FABP3 PROTEIN, HUMAN; FATTY ACID; FATTY ACID BINDING PROTEIN; WATER;

BINDING SITE; CALORIMETRY; CHEMISTRY; HEART MUSCLE; HUMAN; METABOLISM; MOLECULAR DYNAMICS; PROTEIN TERTIARY STRUCTURE; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CALORIMETRY; CRYSTALLOGRAPHY, X-RAY; FATTY ACID-BINDING PROTEINS; FATTY ACIDS; HUMANS; MOLECULAR DYNAMICS SIMULATION; MYOCARDIUM; PROTEIN STRUCTURE, TERTIARY; THERMODYNAMICS; WATER;

EID: 84921445957     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201409830     Document Type: Article

References (20)

1. S. M. Houten, R. J. Wanders, J. Inherited Metab. Dis. 2010, 33, 469-477.
2. R. K. Ockner, J. A. Manning, R. B. Poppenhausen, W. K. L. Ho, Science 1972, 177, 56-58.
3. M. Furuhashi, G. S. Hotamisligil, Nat. Rev. Drug Discovery 2008, 7, 489-503.
4. A. Esteves, R. Ehrlich, Comp. Biochem. Physiol. Part C 2006, 142, 262-274.
5. a) A. C. M. Young, G. Scapin, A. Kromminga, S. B. Patel, J. H. Veerkamp, J. C. Sacchettini, Structure 1994, 2, 523-534;
6. b) G. Zanotti, G. Scapin, P. Spadon, J. H. Veerkamp, J. C. Sacchettini, J. Biol. Chem. 1992, 267, 18541-18550.
7. J. Edqvist, K. Blomqvist, J. Mol. Evol. 2006, 62, 292-306.
8. G. V. Richieri, R. T. Ogata, A.W. Zimmerman, J. H. Veerkamp, A. M. Kleinfeld, Biochemistry 2000, 39, 7197-7204.
9. M. J. McArthur, B. P. Atshaves, A. Frolov, W. D. Foxworth, A. B. Kier, F. Schroeder, J. Lipid Res. 1999, 40, 1371-1383.
10. H. K. Kim, J. Storch, J. Biol. Chem. 1992, 267, 20051-20056.
11. R. L. Smathers, D. R. Petersen, Hum. Genomics 2011, 5, 170-191.
12. W. H. Gerwick, M. Moghaddam, M. Hamberg, Arch. Biochem. Biophys. 1991, 290, 436-444.
13. D. D. Boehr, R. Nussinov, P. E. Wright, Nat. Chem. Biol. 2009, 5, 789-796.
14. a) R. Abel, T. Young, R. Farid, B. J. Berne, R. Friesner, J. Am. Chem. Soc. 2008, 130, 2817-2831;
15. b) B. Breiten, M. R. Lockett, W. Sherman, S. Fujita, M. Al-Sayah, H. Lange, C. M. Bowers, A. Heroux, G. Krilov, G. M. Whitesides, J. Am. Chem. Soc. 2013, 135, 15579-15584.
16. S. Ruskamo, R. P. Yadav, S. Sharma, M. Lehtimäki, S. Laulumaa, S. Aggarwal, M. Simons, J. Bürck, A. S. Ulrich, A. H. Juffer, I. Kursula, P. Kursula, Acta Crystallogr. Sect. D 2014, 70, 165-176.
17. S. Kofler, C. Asam, U. Eckhard, M. Wallner, F. Ferreira, H. Brandstetter, J. Mol. Biol. 2012, 422, 109-123.
18. M. B. Shah, P. R. Wilderman, J. Pascual, Q. Zhang, C. D. Stout, J. R. Halpert, Biochemistry 2012, 51, 7225-7238.
19. R. R. V. Malapaka, S. Khoo, J. Zhang, J. H. Choi, X. E. Zhou, Y. Xu, Y. Gong, J. Li, E.-L. Yong, M. J. Chalmers, L. Chang, J. H. Resau, P. R. Griffin, Y. E. Chen, H. E. Xu, J. Biol. Chem. 2012, 287, 183-195.
20. F. G. Schaap, G. J. van der Vusse, J. F. C. Glatz, Mol. Cell. Biochem. 2002, 239, 69-77.