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Volumn 22, Issue 2, 2015, Pages 144-155

Hepatic expression of miR-122, miR-126, miR-136 and miR-181a and their correlation to histopathological and clinical characteristics of patients with hepatitis C

Author keywords

hepatic expression; hepatitis C; microRNAs; pathohistology and clinics

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; MICRORNA; MICRORNA 122; MICRORNA 126; MICRORNA 136; MICRORNA 181A; UNCLASSIFIED DRUG;

EID: 84921437417     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/jvh.12266     Document Type: Article
Times cited : (22)

References (56)
  • 1
    • 77953290422 scopus 로고    scopus 로고
    • Virus-host interactions in hepatitis C virus infection: Implications for molecular pathogenesis and antiviral strategies
    • Georgel P, Schuster C, Zeisel MB, et al,. Virus-host interactions in hepatitis C virus infection: implications for molecular pathogenesis and antiviral strategies. Trends Mol Med 2010; 16: 277-286.
    • (2010) Trends Mol Med , vol.16 , pp. 277-286
    • Georgel, P.1    Schuster, C.2    Zeisel, M.B.3
  • 2
    • 66649105752 scopus 로고    scopus 로고
    • Gene expression and hepatitis C virus infection
    • Asselah T, Bièche I, Sabbagh A, et al,. Gene expression and hepatitis C virus infection. Gut 2009; 58: 846-858.
    • (2009) Gut , vol.58 , pp. 846-858
    • Asselah, T.1    Bièche, I.2    Sabbagh, A.3
  • 3
    • 47349131565 scopus 로고    scopus 로고
    • Acute hepatitis C: Clinical aspects, diagnosis, and outcome of acute HCV infection
    • Fabris P, Fleming VM, Giordani MT, Barnes E,. Acute hepatitis C: clinical aspects, diagnosis, and outcome of acute HCV infection. Curr Pharm Des 2008; 14: 1661-1665.
    • (2008) Curr Pharm des , vol.14 , pp. 1661-1665
    • Fabris, P.1    Fleming, V.M.2    Giordani, M.T.3    Barnes, E.4
  • 4
    • 65349153811 scopus 로고    scopus 로고
    • The hepatitis C virus enigma
    • Myrmel H, Ulvestad E, Asjø B,. The hepatitis C virus enigma. APMIS 2009; 117: 427-439.
    • (2009) APMIS , vol.117 , pp. 427-439
    • Myrmel, H.1    Ulvestad, E.2    Asjø, B.3
  • 5
    • 25844523297 scopus 로고    scopus 로고
    • Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes
    • Simmonds P, Bukh J, Combet C, et al,. Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes. Hepatology 2005; 42: 962-973.
    • (2005) Hepatology , vol.42 , pp. 962-973
    • Simmonds, P.1    Bukh, J.2    Combet, C.3
  • 6
    • 65649111753 scopus 로고    scopus 로고
    • MicroRNA signatures in liver diseases
    • Chen XM,. MicroRNA signatures in liver diseases. World J Gastroenterol 2009; 15: 1665-1672.
    • (2009) World J Gastroenterol , vol.15 , pp. 1665-1672
    • Chen, X.M.1
  • 7
    • 24644483623 scopus 로고    scopus 로고
    • Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA
    • Jopling CL, Yi M, Lancaster AM, Lemon SM, Sarnow P,. Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science 2005; 309: 1577-1581.
    • (2005) Science , vol.309 , pp. 1577-1581
    • Jopling, C.L.1    Yi, M.2    Lancaster, A.M.3    Lemon, S.M.4    Sarnow, P.5
  • 8
    • 84872192531 scopus 로고    scopus 로고
    • MicroRNA-122-dependent and -independent replication of Hepatitis C Virus in Hep3B human hepatoma cells
    • Thibault PA, Huys A, Dhillon P, Wilson JA,. MicroRNA-122-dependent and -independent replication of Hepatitis C Virus in Hep3B human hepatoma cells. Virology 2013; 436: 179-190.
    • (2013) Virology , vol.436 , pp. 179-190
    • Thibault, P.A.1    Huys, A.2    Dhillon, P.3    Wilson, J.A.4
  • 9
    • 79953201904 scopus 로고    scopus 로고
    • MicroRNA-122 antagonism against hepatitis C virus genotypes 1-6 and reduced efficacy by host RNA insertion or mutations in the HCV 5' UTR
    • Li YP, Gottwein JM, Scheel TK, Jensen TB, Bukh J,. MicroRNA-122 antagonism against hepatitis C virus genotypes 1-6 and reduced efficacy by host RNA insertion or mutations in the HCV 5' UTR. Proc Natl Acad Sci U S A 2011; 108: 4991-4996.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 4991-4996
    • Li, Y.P.1    Gottwein, J.M.2    Scheel, T.K.3    Jensen, T.B.4    Bukh, J.5
  • 10
    • 84861986230 scopus 로고    scopus 로고
    • MicroRNAs and hepatitis C virus: Toward the end of miR-122 supremacy
    • Hoffmann TW, Duverlie G, Bengrine A,. MicroRNAs and hepatitis C virus: toward the end of miR-122 supremacy. Virol J 2012; 9: 109.
    • (2012) Virol J , vol.9 , pp. 109
    • Hoffmann, T.W.1    Duverlie, G.2    Bengrine, A.3
  • 11
    • 59349098653 scopus 로고    scopus 로고
    • Regulation of the hepatitis C virus genome replication by miR-199a
    • Murakami Y, Aly HH, Tajima A, Inoue I, Shimotohno K,. Regulation of the hepatitis C virus genome replication by miR-199a. J Hepatol 2009; 50: 453-460.
    • (2009) J Hepatol , vol.50 , pp. 453-460
    • Murakami, Y.1    Aly, H.H.2    Tajima, A.3    Inoue, I.4    Shimotohno, K.5
  • 12
    • 84864368867 scopus 로고    scopus 로고
    • Let-7b is a novel regulator of hepatitis C virus replication
    • Cheng JC, Yeh YJ, Tseng CP, et al,. Let-7b is a novel regulator of hepatitis C virus replication. Cell Mol Life Sci 2012; 69: 2621-2633.
    • (2012) Cell Mol Life Sci , vol.69 , pp. 2621-2633
    • Cheng, J.C.1    Yeh, Y.J.2    Tseng, C.P.3
  • 13
    • 79952466910 scopus 로고    scopus 로고
    • Clinical significance and potential of hepatic microRNA-122 expression in hepatitis C
    • Morita K, Taketomi A, Shirabe K, et al,. Clinical significance and potential of hepatic microRNA-122 expression in hepatitis C. Liver Int 2011; 31: 474-484.
    • (2011) Liver Int , vol.31 , pp. 474-484
    • Morita, K.1    Taketomi, A.2    Shirabe, K.3
  • 14
    • 75649139134 scopus 로고    scopus 로고
    • Physiological and pathological roles for microRNAs in the immune system
    • O'Connell RM, Rao DS, Chaudhuri AA, Baltimore D,. Physiological and pathological roles for microRNAs in the immune system. Nat Rev Immunol 2010; 10: 111-122.
    • (2010) Nat Rev Immunol , vol.10 , pp. 111-122
    • O'Connell, R.M.1    Rao, D.S.2    Chaudhuri, A.A.3    Baltimore, D.4
  • 15
    • 34548277150 scopus 로고    scopus 로고
    • Grading and staging systems for inflammation and fibrosis in chronic liver diseases
    • Goodman ZD,. Grading and staging systems for inflammation and fibrosis in chronic liver diseases. J Hepatol 2007; 47: 598-607.
    • (2007) J Hepatol , vol.47 , pp. 598-607
    • Goodman, Z.D.1
  • 16
    • 0029778988 scopus 로고    scopus 로고
    • An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group
    • Bedossa P, Poynard T,. An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group. Hepatology 1996; 24: 289-293.
    • (1996) Hepatology , vol.24 , pp. 289-293
    • Bedossa, P.1    Poynard, T.2
  • 17
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD,. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 18
    • 20944450160 scopus 로고    scopus 로고
    • Combinatorial microRNA target predictions
    • Krek A, Grün D, Poy MN, et al,. Combinatorial microRNA target predictions. Nat Genet 2005; 37: 495-500.
    • (2005) Nat Genet , vol.37 , pp. 495-500
    • Krek, A.1    Grün, D.2    Poy, M.N.3
  • 20
    • 44149083586 scopus 로고    scopus 로고
    • MiRDB: A microRNA target prediction and functional annotation database with a wiki interface
    • Wang X,. miRDB: a microRNA target prediction and functional annotation database with a wiki interface. RNA 2008; 14: 1012-1017.
    • (2008) RNA , vol.14 , pp. 1012-1017
    • Wang, X.1
  • 21
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang DW, Sherman BT, Lempicki RA,. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009; 4: 44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 22
    • 31044444975 scopus 로고    scopus 로고
    • TarBase: A comprehensive database of experimentally supported animal microRNA targets
    • Sethupathy P, Corda B, Hatzigeorgiou AG,. TarBase: a comprehensive database of experimentally supported animal microRNA targets. RNA 2006; 12: 192-197.
    • (2006) RNA , vol.12 , pp. 192-197
    • Sethupathy, P.1    Corda, B.2    Hatzigeorgiou, A.G.3
  • 24
    • 37349008944 scopus 로고    scopus 로고
    • MiRNApath: A database of miRNAs, target genes and metabolic pathways
    • Chiromatzo AO, Oliveira TY, Pereira G, et al,. miRNApath: a database of miRNAs, target genes and metabolic pathways. Genet Mol Res 2007; 6: 859-865.
    • (2007) Genet Mol Res , vol.6 , pp. 859-865
    • Chiromatzo, A.O.1    Oliveira, T.Y.2    Pereira, G.3
  • 25
    • 77955286897 scopus 로고    scopus 로고
    • TAM: A method for enrichment and depletion analysis of a microRNA category in a list of microRNAs
    • Lu M, Shi B, Wang J, Cao Q, Cui Q,. TAM: a method for enrichment and depletion analysis of a microRNA category in a list of microRNAs. BMC Bioinformatics 2010; 11: 419.
    • (2010) BMC Bioinformatics , vol.11 , pp. 419
    • Lu, M.1    Shi, B.2    Wang, J.3    Cao, Q.4    Cui, Q.5
  • 26
    • 54849408182 scopus 로고    scopus 로고
    • An analysis of human microRNA and disease associations
    • Lu M, Zhang Q, Deng M, et al,. An analysis of human microRNA and disease associations. PLoSONE 2008; 3: e3420.
    • (2008) PLoSONE , vol.3 , pp. e3420
    • Lu, M.1    Zhang, Q.2    Deng, M.3
  • 27
    • 84860580525 scopus 로고    scopus 로고
    • 'Immune activation, aging and gender' and progression of liver disease
    • Nasta P,. 'Immune activation, aging and gender' and progression of liver disease. Acta Biomed 2011; 82: 115-123.
    • (2011) Acta Biomed , vol.82 , pp. 115-123
    • Nasta, P.1
  • 28
    • 84870293512 scopus 로고    scopus 로고
    • Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity
    • Li G, Yu M, Lee WW, et al,. Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity. Nat Med 2012; 18: 1518-1524.
    • (2012) Nat Med , vol.18 , pp. 1518-1524
    • Li, G.1    Yu, M.2    Lee, W.W.3
  • 29
    • 78649674133 scopus 로고    scopus 로고
    • Correlation between microRNA expression levels and clinical parameters associated with chronic hepatitis C viral infection in humans
    • Marquez RT, Bandyopadhyay S, Wendlandt EB, et al,. Correlation between microRNA expression levels and clinical parameters associated with chronic hepatitis C viral infection in humans. Lab Invest 2010; 90: 1727-1736.
    • (2010) Lab Invest , vol.90 , pp. 1727-1736
    • Marquez, R.T.1    Bandyopadhyay, S.2    Wendlandt, E.B.3
  • 30
    • 77955922623 scopus 로고    scopus 로고
    • Testosterone-induced upregulation of miRNAs in the female mouse liver
    • Delic D, Grosser C, Dkhil M, Al-Quraishy S, Wunderlich F,. Testosterone-induced upregulation of miRNAs in the female mouse liver. Steroids 2010; 75: 998-1004.
    • (2010) Steroids , vol.75 , pp. 998-1004
    • Delic, D.1    Grosser, C.2    Dkhil, M.3    Al-Quraishy, S.4    Wunderlich, F.5
  • 31
    • 78650810019 scopus 로고    scopus 로고
    • Role of insulin resistance and hepatic steatosis in the progression of fibrosis and response to treatment in hepatitis C
    • Sanyal AJ,. Role of insulin resistance and hepatic steatosis in the progression of fibrosis and response to treatment in hepatitis C. Liver Int 2011; 31 (Suppl 1): 23-28.
    • (2011) Liver Int , vol.31 , pp. 23-28
    • Sanyal, A.J.1
  • 32
    • 84883752818 scopus 로고    scopus 로고
    • MicroRNA 'signature' during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention
    • Munagala R, Aqil F, Vadhanam MV, Gupta RC,. MicroRNA 'signature' during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention. Cancer Lett 2013; 339: 175-184.
    • (2013) Cancer Lett , vol.339 , pp. 175-184
    • Munagala, R.1    Aqil, F.2    Vadhanam, M.V.3    Gupta, R.C.4
  • 33
    • 84907430866 scopus 로고    scopus 로고
    • Estrogen Regulation of MicroRNAs, Target Genes, and MicroRNA Expression Associated with Vitellogenesis in the Zebrafish
    • Cohen A, Smith Y,. Estrogen Regulation of MicroRNAs, Target Genes, and MicroRNA Expression Associated with Vitellogenesis in the Zebrafish. Zebrafish 2013. doi: 10.1089/zeb.2013.0873.
    • (2013) Zebrafish
    • Cohen, A.1    Smith, Y.2
  • 34
    • 58149333128 scopus 로고    scopus 로고
    • Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy
    • Sarasin-Filipowicz M, Krol J, Markiewicz I, Heim MH, Filipowicz W,. Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy. Nat Med 2009; 15: 31-33.
    • (2009) Nat Med , vol.15 , pp. 31-33
    • Sarasin-Filipowicz, M.1    Krol, J.2    Markiewicz, I.3    Heim, M.H.4    Filipowicz, W.5
  • 36
    • 79960514244 scopus 로고    scopus 로고
    • Overexpression of gankyrin induces liver steatosis in zebrafish (Danio rerio)
    • Her GM, Hsu CC, Hong JR, et al,. Overexpression of gankyrin induces liver steatosis in zebrafish (Danio rerio). Biochim Biophys Acta 2011; 1811: 536-548.
    • (2011) Biochim Biophys Acta , vol.1811 , pp. 536-548
    • Her, G.M.1    Hsu, C.C.2    Hong, J.R.3
  • 37
    • 84856032592 scopus 로고    scopus 로고
    • New insights into HCV replication: Potential antiviral targets
    • Rice CM,. New insights into HCV replication: potential antiviral targets. Top Antivir Med 2011; 19: 117-120.
    • (2011) Top Antivir Med , vol.19 , pp. 117-120
    • Rice, C.M.1
  • 38
    • 78149442860 scopus 로고    scopus 로고
    • Expression of versican 3'-untranslated region modulates endogenous microRNA functions
    • Lee DY, Jeyapalan Z, Fang L, et al,. Expression of versican 3'-untranslated region modulates endogenous microRNA functions. PLoS ONE 2010; 5: e13599.
    • (2010) PLoS ONE , vol.5 , pp. e13599
    • Lee, D.Y.1    Jeyapalan, Z.2    Fang, L.3
  • 39
    • 84867572569 scopus 로고    scopus 로고
    • MiR-136 promotes apoptosis of glioma cells by targeting AEG-1 and Bcl-2
    • Yang Y, Wu J, Guan H, et al,. MiR-136 promotes apoptosis of glioma cells by targeting AEG-1 and Bcl-2. FEBS Lett 2012; 586: 3608-3612.
    • (2012) FEBS Lett , vol.586 , pp. 3608-3612
    • Yang, Y.1    Wu, J.2    Guan, H.3
  • 40
    • 79959537058 scopus 로고    scopus 로고
    • Down-regulation of phosphatase and tensin homolog by hepatitis C virus core 3a in hepatocytes triggers the formation of large lipid droplets
    • Clément S, Peyrou M, Sanchez-Pareja A, et al,. Down-regulation of phosphatase and tensin homolog by hepatitis C virus core 3a in hepatocytes triggers the formation of large lipid droplets. Hepatology 2011; 54: 38-49.
    • (2011) Hepatology , vol.54 , pp. 38-49
    • Clément, S.1    Peyrou, M.2    Sanchez-Pareja, A.3
  • 41
    • 2342559886 scopus 로고    scopus 로고
    • Steatosis and liver cell apoptosis in chronic hepatitis C: A mechanism for increased liver injury
    • Walsh MJ, Vanags DM, Clouston AD, et al,. Steatosis and liver cell apoptosis in chronic hepatitis C: a mechanism for increased liver injury. Hepatology 2004; 39: 1230-1238.
    • (2004) Hepatology , vol.39 , pp. 1230-1238
    • Walsh, M.J.1    Vanags, D.M.2    Clouston, A.D.3
  • 42
    • 84921435870 scopus 로고    scopus 로고
    • Patohistological features of chronic viral hepatitis as a diagnostic challenge
    • Luzar B. Vizjak A. Volavšek M. Popovic M. Franchi A. eds. Ljubljana: Institute of pathology, Faculty of medicine.
    • Ferlan-Marolt V,. Patohistological features of chronic viral hepatitis as a diagnostic challenge. In:, Luzar B, Vizjak A, Volavšek M, Popovic M, Franchi A, eds. News in Pathology: Celebrating 70th Anniversary of the Institute of Pathology, Faculty of Medicine, University of Ljubljana. Ljubljana: Institute of pathology, Faculty of medicine, 2010: 197-200.
    • (2010) News in Pathology: Celebrating 70th Anniversary of the Institute of Pathology, Faculty of Medicine, University of Ljubljana , pp. 197-200
    • Ferlan-Marolt, V.1
  • 43
    • 74049085924 scopus 로고    scopus 로고
    • Emerging role of microRNAs in liver diseases
    • Bala S, Marcos M, Szabo G,. Emerging role of microRNAs in liver diseases. World J Gastroenterol 2009; 15: 5633-5640.
    • (2009) World J Gastroenterol , vol.15 , pp. 5633-5640
    • Bala, S.1    Marcos, M.2    Szabo, G.3
  • 44
    • 52449100144 scopus 로고    scopus 로고
    • Role of microRNAs in vascular diseases, inflammation, and angiogenesis
    • Urbich C, Kuehbacher A, Dimmeler S,. Role of microRNAs in vascular diseases, inflammation, and angiogenesis. Cardiovasc Res 2008; 79: 581-588.
    • (2008) Cardiovasc Res , vol.79 , pp. 581-588
    • Urbich, C.1    Kuehbacher, A.2    Dimmeler, S.3
  • 45
    • 56749185827 scopus 로고    scopus 로고
    • Adding fuel to fire: MicroRNAs as a new class of mediators of inflammation
    • Sheedy FJ, O'Neill LA,. Adding fuel to fire: microRNAs as a new class of mediators of inflammation. Ann Rheum Dis 2008; 67 (Suppl 3): iii50-iii55.
    • (2008) Ann Rheum Dis , vol.67 , pp. iii50-iii55
    • Sheedy, F.J.1    O'Neill, L.A.2
  • 46
    • 75849132381 scopus 로고    scopus 로고
    • Systematic identification of microRNA and messenger RNA profiles in hepatitis C virus-infected human hepatoma cells
    • Liu X, Wang T, Wakita T, Yang W,. Systematic identification of microRNA and messenger RNA profiles in hepatitis C virus-infected human hepatoma cells. Virology 2010; 398: 57-67.
    • (2010) Virology , vol.398 , pp. 57-67
    • Liu, X.1    Wang, T.2    Wakita, T.3    Yang, W.4
  • 47
    • 78349251242 scopus 로고    scopus 로고
    • MiR-126 and miR-126: New players in cancer
    • Meister J, Schmidt MH,. miR-126 and miR-126: new players in cancer. Sci World J 2010; 10: 2090-2100.
    • (2010) Sci World J , vol.10 , pp. 2090-2100
    • Meister, J.1    Schmidt, M.H.2
  • 48
    • 84855675933 scopus 로고    scopus 로고
    • Steatosis and insulin resistance in response to treatment of chronic hepatitis C
    • Negro F,. Steatosis and insulin resistance in response to treatment of chronic hepatitis C. J Viral Hepat 2012; 19 (Suppl 1): 42-47.
    • (2012) J Viral Hepat , vol.19 , pp. 42-47
    • Negro, F.1
  • 50
    • 84872376663 scopus 로고    scopus 로고
    • Hepatic and serum levels of miR-122 after chronic HCV-induced fibrosis
    • Trebicka J, Anadol E, Elfimova N, et al,. Hepatic and serum levels of miR-122 after chronic HCV-induced fibrosis. J Hepatol 2013; 58: 234-239.
    • (2013) J Hepatol , vol.58 , pp. 234-239
    • Trebicka, J.1    Anadol, E.2    Elfimova, N.3
  • 51
    • 80052707667 scopus 로고    scopus 로고
    • Molecular pathogenesis of hepatic fibrosis and current therapeutic approaches
    • Mormone E, George J, Nieto N,. Molecular pathogenesis of hepatic fibrosis and current therapeutic approaches. Chem Biol Interact 2011; 193: 225-231.
    • (2011) Chem Biol Interact , vol.193 , pp. 225-231
    • Mormone, E.1    George, J.2    Nieto, N.3
  • 52
    • 0036317905 scopus 로고    scopus 로고
    • Expression of bcl-2 oncoprotein in cases of acute and chronic viral hepatitis type B and type C: A clinicopathologic study
    • Tsamandas AC, Thomopoulos K, Gogos C, et al,. Expression of bcl-2 oncoprotein in cases of acute and chronic viral hepatitis type B and type C: a clinicopathologic study. Dig Dis Sci 2002; 47: 1618-1624.
    • (2002) Dig Dis Sci , vol.47 , pp. 1618-1624
    • Tsamandas, A.C.1    Thomopoulos, K.2    Gogos, C.3
  • 53
    • 0345731363 scopus 로고    scopus 로고
    • Potential role of bcl-2 and bax mRNA and protein expression in chronic hepatitis type B and C: A clinicopathologic study
    • Tsamandas AC, Thomopoulos K, Zolota V, et al,. Potential role of bcl-2 and bax mRNA and protein expression in chronic hepatitis type B and C: a clinicopathologic study. Mod Pathol 2003; 16: 1273-1288.
    • (2003) Mod Pathol , vol.16 , pp. 1273-1288
    • Tsamandas, A.C.1    Thomopoulos, K.2    Zolota, V.3
  • 54
    • 34249814297 scopus 로고    scopus 로고
    • Expression of Bax, Bcl-xL and Bcl-2 proteins in relation to grade of inflammation and stage offibrosis in chronic hepatitis C
    • Piekarska A, Kubiak R, Omulecka A, Szymczak W, Piekarski J,. Expression of Bax, Bcl-xL and Bcl-2 proteins in relation to grade of inflammation and stage offibrosis in chronic hepatitis C. Histopathology 2007; 50: 928-935.
    • (2007) Histopathology , vol.50 , pp. 928-935
    • Piekarska, A.1    Kubiak, R.2    Omulecka, A.3    Szymczak, W.4    Piekarski, J.5
  • 55
    • 0034001484 scopus 로고    scopus 로고
    • Correlation of genotypes and route of transmission with histologic activity and disease stage in chronic hepatitis C
    • Ramalho F, Costa A, Pires A, et al,. Correlation of genotypes and route of transmission with histologic activity and disease stage in chronic hepatitis C. Dig Dis Sci 2000; 45: 182-187.
    • (2000) Dig Dis Sci , vol.45 , pp. 182-187
    • Ramalho, F.1    Costa, A.2    Pires, A.3
  • 56
    • 84873459086 scopus 로고    scopus 로고
    • Sensitive detection of hepatocellular injury in chronic hepatitis C patients with circulating hepatocyte-derived microRNA-122
    • van der Meer AJ, Farid WR, Sonneveld MJ, et al,. Sensitive detection of hepatocellular injury in chronic hepatitis C patients with circulating hepatocyte-derived microRNA-122. J Viral Hepat 2013; 20: 158-166.
    • (2013) J Viral Hepat , vol.20 , pp. 158-166
    • Van Der Meer, A.J.1    Farid, W.R.2    Sonneveld, M.J.3


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