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Volumn 260, Issue , 2015, Pages 16-24

An agent-based modeling framework linking inflammation and cancer using evolutionary principles: Description of a generative hierarchy for the hallmarks of cancer and developing a bridge between mechanism and epidemiological data

Author keywords

Agent based modeling; Cancer; Computational biology; Evolution; Inflammation; Systems biology

Indexed keywords

AUTONOMOUS AGENTS; COMPUTATIONAL METHODS; DIGITAL STORAGE; DISEASES; PATHOLOGY; SIMULATION PLATFORM;

EID: 84921433780     PISSN: 00255564     EISSN: 18793134     Source Type: Journal    
DOI: 10.1016/j.mbs.2014.07.009     Document Type: Article
Times cited : (19)

References (41)
  • 1
    • 84859401430 scopus 로고    scopus 로고
    • Cancer and inflammation: an old intuition with rapidly evolving new concepts
    • Trinchieri G. Cancer and inflammation: an old intuition with rapidly evolving new concepts. Annu. Rev. Immunol. 2012, 30:677-706.
    • (2012) Annu. Rev. Immunol. , vol.30 , pp. 677-706
    • Trinchieri, G.1
  • 2
    • 84888633713 scopus 로고    scopus 로고
    • Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms
    • Elinav E., et al. Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms. Nat. Rev. Cancer 2013, 13(11):759-771.
    • (2013) Nat. Rev. Cancer , vol.13 , Issue.11 , pp. 759-771
    • Elinav, E.1
  • 3
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov S.I., Greten F.R., Karin M. Immunity, inflammation, and cancer. Cell 2010, 140(6):883-899.
    • (2010) Cell , vol.140 , Issue.6 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 4
    • 75849117800 scopus 로고    scopus 로고
    • Inflammation and oncogenesis: a vicious connection
    • Grivennikov S.I., Karin M. Inflammation and oncogenesis: a vicious connection. Curr. Opin. Genet. Dev. 2010, 20(1):65-71.
    • (2010) Curr. Opin. Genet. Dev. , vol.20 , Issue.1 , pp. 65-71
    • Grivennikov, S.I.1    Karin, M.2
  • 5
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144(5):646-674.
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 6
    • 84860467522 scopus 로고    scopus 로고
    • Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials
    • Algra A.M., Rothwell P.M. Effects of regular aspirin on long-term cancer incidence and metastasis: a systematic comparison of evidence from observational studies versus randomised trials. Lancet Oncol. 2012, 13(5):518-527.
    • (2012) Lancet Oncol. , vol.13 , Issue.5 , pp. 518-527
    • Algra, A.M.1    Rothwell, P.M.2
  • 7
    • 84863412124 scopus 로고    scopus 로고
    • Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials
    • Rothwell P.M., et al. Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials. Lancet 2012, 379(9826):1602-1612.
    • (2012) Lancet , vol.379 , Issue.9826 , pp. 1602-1612
    • Rothwell, P.M.1
  • 8
    • 67650151005 scopus 로고    scopus 로고
    • Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
    • Colotta F., et al. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis 2009, 30(7):1073-1081.
    • (2009) Carcinogenesis , vol.30 , Issue.7 , pp. 1073-1081
    • Colotta, F.1
  • 9
    • 45749134564 scopus 로고    scopus 로고
    • The anticancer immune response: indispensable for therapeutic success?
    • Zitvogel L., et al. The anticancer immune response: indispensable for therapeutic success?. J. Clin. Invest. 2008, 118(6):1991-2001.
    • (2008) J. Clin. Invest. , vol.118 , Issue.6 , pp. 1991-2001
    • Zitvogel, L.1
  • 10
    • 0037180812 scopus 로고    scopus 로고
    • Points of control in inflammation
    • Nathan C. Points of control in inflammation. Nature 2002, 420(6917):846-852.
    • (2002) Nature , vol.420 , Issue.6917 , pp. 846-852
    • Nathan, C.1
  • 11
    • 77950365906 scopus 로고    scopus 로고
    • Nonresolving inflammation
    • Nathan C., Ding A. Nonresolving inflammation. Cell 2010, 140(6):871-882.
    • (2010) Cell , vol.140 , Issue.6 , pp. 871-882
    • Nathan, C.1    Ding, A.2
  • 12
    • 43249089766 scopus 로고    scopus 로고
    • Translational systems biology of inflammation
    • Vodovotz Y., et al. Translational systems biology of inflammation. PLoS Comput. Biol. 2008, 4(4):e1000014.
    • (2008) PLoS Comput. Biol. , vol.4 , Issue.4 , pp. e1000014
    • Vodovotz, Y.1
  • 13
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., Weinberg R.A. The hallmarks of cancer. Cell 2000, 100(1):57-70.
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 14
    • 70350215756 scopus 로고    scopus 로고
    • At the biological modeling and simulation frontier
    • Hunt C.A., et al. At the biological modeling and simulation frontier. Pharm. Res. 2009.
    • (2009) Pharm. Res.
    • Hunt, C.A.1
  • 16
    • 84877991231 scopus 로고    scopus 로고
    • Examining the pathogenesis of breast cancer using a novel agent-based model of mammary ductal epithelium dynamics
    • Chapa J., et al. Examining the pathogenesis of breast cancer using a novel agent-based model of mammary ductal epithelium dynamics. PLoS ONE 2013, 8(5):e64091.
    • (2013) PLoS ONE , vol.8 , Issue.5 , pp. e64091
    • Chapa, J.1
  • 17
    • 0035491584 scopus 로고    scopus 로고
    • Agent-based computer simulation and sirs: building a bridge between basic science and clinical trials
    • An G. Agent-based computer simulation and sirs: building a bridge between basic science and clinical trials. Shock 2001, 16(4):266-273.
    • (2001) Shock , vol.16 , Issue.4 , pp. 266-273
    • An, G.1
  • 18
    • 4744344132 scopus 로고    scopus 로고
    • In silico experiments of existing and hypothetical cytokine-directed clinical trials using agent-based modeling
    • An G. In silico experiments of existing and hypothetical cytokine-directed clinical trials using agent-based modeling. Crit. Care Med. 2004, 32(10):2050-2060.
    • (2004) Crit. Care Med. , vol.32 , Issue.10 , pp. 2050-2060
    • An, G.1
  • 19
    • 46449119246 scopus 로고    scopus 로고
    • Introduction of an agent-based multi-scale modular architecture for dynamic knowledge representation of acute inflammation
    • An G. Introduction of an agent-based multi-scale modular architecture for dynamic knowledge representation of acute inflammation. Theor. Biol. Med. Model 2008, 5(1):11.
    • (2008) Theor. Biol. Med. Model , vol.5 , Issue.1 , pp. 11
    • An, G.1
  • 20
    • 0036500834 scopus 로고    scopus 로고
    • Reverse engineering of biological complexity
    • Csete M.E., Doyle J.C. Reverse engineering of biological complexity. Science 2002, 295(5560):1664-1669.
    • (2002) Science , vol.295 , Issue.5560 , pp. 1664-1669
    • Csete, M.E.1    Doyle, J.C.2
  • 21
    • 27844574799 scopus 로고    scopus 로고
    • Motifs, control, and stability
    • Doyle J., Csete M. Motifs, control, and stability. PLoS Biol. 2005, 3(11):e392.
    • (2005) PLoS Biol. , vol.3 , Issue.11 , pp. e392
    • Doyle, J.1    Csete, M.2
  • 22
    • 80053153518 scopus 로고    scopus 로고
    • Architecture, constraints, and behavior
    • Doyle J.C., Csete M. Architecture, constraints, and behavior. Proc. Natl. Acad. Sci. USA 2011, 108(Suppl 3):15624-15630.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 15624-15630
    • Doyle, J.C.1    Csete, M.2
  • 23
    • 84921436118 scopus 로고
    • Proceedings of the 4th Berkely Symposium on Mathematics and Probability
    • University of California Press, Berkeley, CA
    • M. Eden, Proceedings of the 4th Berkely Symposium on Mathematics and Probability, in: 4th Berkeley Symposium on Mathematics and Probability, University of California Press, Berkeley, CA, 1961.
    • (1961) 4th Berkeley Symposium on Mathematics and Probability
    • Eden, M.1
  • 24
    • 84921436143 scopus 로고    scopus 로고
    • Cancer Intervention and Surveillance Modeling Network: Breast Cancer Modeling. (cited 30.04.14)
    • Institute, N.C. Cancer Intervention and Surveillance Modeling Network: Breast Cancer Modeling. (cited 30.04.14). http://cisnet.cancer.gov/breast/profiles.html.
    • Institute, N.C.1
  • 25
    • 33751413561 scopus 로고    scopus 로고
    • Physiologically based synthetic models of hepatic disposition
    • Hunt C.A., et al. Physiologically based synthetic models of hepatic disposition. J. Pharmacokinet Pharmacodyn. 2006, 33(6):737-772.
    • (2006) J. Pharmacokinet Pharmacodyn. , vol.33 , Issue.6 , pp. 737-772
    • Hunt, C.A.1
  • 26
    • 76349087592 scopus 로고    scopus 로고
    • A computational approach to resolve cell level contributions to early glandular epithelial cancer progression
    • Kim S.H., et al. A computational approach to resolve cell level contributions to early glandular epithelial cancer progression. BMC Syst. Biol. 2009, 3:122.
    • (2009) BMC Syst. Biol. , vol.3 , pp. 122
    • Kim, S.H.1
  • 27
    • 79955559185 scopus 로고    scopus 로고
    • MDCK cystogenesis driven by cell stabilization within computational analogues
    • Engelberg J.A., et al. MDCK cystogenesis driven by cell stabilization within computational analogues. PLoS Comput. Biol. 2011, 7(4):e1002030.
    • (2011) PLoS Comput. Biol. , vol.7 , Issue.4 , pp. e1002030
    • Engelberg, J.A.1
  • 28
    • 64949187961 scopus 로고    scopus 로고
    • Essential operating principles for tumor spheroid growth
    • Engelberg J.A., Ropella G.E., Hunt C.A. Essential operating principles for tumor spheroid growth. BMC Syst. Biol. 2008, 2:110.
    • (2008) BMC Syst. Biol. , vol.2 , pp. 110
    • Engelberg, J.A.1    Ropella, G.E.2    Hunt, C.A.3
  • 29
    • 84879115621 scopus 로고    scopus 로고
    • Tumor-immune dynamics regulated in the microenvironment inform the transient nature of immune-induced tumor dormancy
    • Wilkie K.P., Hahnfeldt P. Tumor-immune dynamics regulated in the microenvironment inform the transient nature of immune-induced tumor dormancy. Cancer Res. 2013, 73(12):3534-3544.
    • (2013) Cancer Res. , vol.73 , Issue.12 , pp. 3534-3544
    • Wilkie, K.P.1    Hahnfeldt, P.2
  • 30
    • 84879441264 scopus 로고    scopus 로고
    • Mathematical models of immune-induced cancer dormancy and the emergence of immune evasion
    • Wilkie K.P., Hahnfeldt P. Mathematical models of immune-induced cancer dormancy and the emergence of immune evasion. Interface Focus 2013, 3(4):20130010.
    • (2013) Interface Focus , vol.3 , Issue.4 , pp. 20130010
    • Wilkie, K.P.1    Hahnfeldt, P.2
  • 31
    • 84864210268 scopus 로고    scopus 로고
    • Immunoediting: evidence of the multifaceted role of the immune system in self-metastatic tumor growth
    • Enderling H., Hlatky L., Hahnfeldt P. Immunoediting: evidence of the multifaceted role of the immune system in self-metastatic tumor growth. Theor. Biol. Med. Model 2012, 9:31.
    • (2012) Theor. Biol. Med. Model , vol.9 , pp. 31
    • Enderling, H.1    Hlatky, L.2    Hahnfeldt, P.3
  • 32
    • 84872650905 scopus 로고    scopus 로고
    • The tumor growth paradox and immune system-mediated selection for cancer stem cells
    • Hillen T., Enderling H., Hahnfeldt P. The tumor growth paradox and immune system-mediated selection for cancer stem cells. Bull. Math. Biol. 2013, 75(1):161-184.
    • (2013) Bull. Math. Biol. , vol.75 , Issue.1 , pp. 161-184
    • Hillen, T.1    Enderling, H.2    Hahnfeldt, P.3
  • 33
    • 0026773381 scopus 로고
    • Oncogenes, anti-oncogenes and the immune response to cancer: a mathematical model
    • Sherratt J.A., Nowak M.A. Oncogenes, anti-oncogenes and the immune response to cancer: a mathematical model. Proc. Biol. Sci. 1992, 248(1323):261-271.
    • (1992) Proc. Biol. Sci. , vol.248 , Issue.1323 , pp. 261-271
    • Sherratt, J.A.1    Nowak, M.A.2
  • 34
    • 84877032711 scopus 로고    scopus 로고
    • On optimal chemotherapy with a strongly targeted agent for a model of tumor-immune system interactions with generalized logistic growth
    • Ledzewicz U., Olumoye O., Schattler H. On optimal chemotherapy with a strongly targeted agent for a model of tumor-immune system interactions with generalized logistic growth. Math Biosci. Eng. 2013, 10(3):787-802.
    • (2013) Math Biosci. Eng. , vol.10 , Issue.3 , pp. 787-802
    • Ledzewicz, U.1    Olumoye, O.2    Schattler, H.3
  • 35
    • 34447501892 scopus 로고    scopus 로고
    • Cancer immunotherapy, mathematical modeling and optimal control
    • Castiglione F., Piccoli B. Cancer immunotherapy, mathematical modeling and optimal control. J. Theor. Biol. 2007, 247(4):723-732.
    • (2007) J. Theor. Biol. , vol.247 , Issue.4 , pp. 723-732
    • Castiglione, F.1    Piccoli, B.2
  • 36
    • 84866538931 scopus 로고    scopus 로고
    • Evasion of tumours from the control of the immune system: consequences of brief encounters
    • Al-Tameemi M., Chaplain M., d'Onofrio A. Evasion of tumours from the control of the immune system: consequences of brief encounters. Biol. Direct 2012, 7:31.
    • (2012) Biol. Direct , vol.7 , pp. 31
    • Al-Tameemi, M.1    Chaplain, M.2    d'Onofrio, A.3
  • 38
    • 0242322492 scopus 로고    scopus 로고
    • The universal dynamics of tumor growth
    • Bru A., et al. The universal dynamics of tumor growth. Biophys. J. 2003, 85(5):2948-2961.
    • (2003) Biophys. J. , vol.85 , Issue.5 , pp. 2948-2961
    • Bru, A.1
  • 39
    • 33744960226 scopus 로고    scopus 로고
    • Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study
    • Carey L.A., et al. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA 2006, 295(21):2492-2502.
    • (2006) JAMA , vol.295 , Issue.21 , pp. 2492-2502
    • Carey, L.A.1
  • 40
    • 68149163711 scopus 로고    scopus 로고
    • Triple-negative breast cancers are increased in black women regardless of age or body mass index
    • Stead L.A., et al. Triple-negative breast cancers are increased in black women regardless of age or body mass index. Breast Cancer Res. 2009, 11(2):R18.
    • (2009) Breast Cancer Res. , vol.11 , Issue.2 , pp. R18
    • Stead, L.A.1
  • 41
    • 84866070927 scopus 로고    scopus 로고
    • Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women
    • Reiner A.P., et al. Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American women. Am. J. Hum. Genet. 2012, 91(3):502-512.
    • (2012) Am. J. Hum. Genet. , vol.91 , Issue.3 , pp. 502-512
    • Reiner, A.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.