Tyrosine phosphorylation of WIP releases bound WASP and impairs podosome assembly in macrophages

Journal of Cell Science

Volumn 128, Issue 2, 2015, Pages 251-265

  Vijayakumar, Vineetha ^a   Monypenny, James ^a   Chen, Xing Judy ^a   Machesky, Laura M ^b   Lilla, Sergio ^b   Thrasher, Adrian J ^c   Antón, Inés M ^d   Calle, Yolanda ^e,f   Jones, Gareth E ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^e KING'S COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF ROEHAMPTON   (United Kingdom)

Author keywords

Actin cytoskeleton; Macrophages; Matrix degradation; Podosome; Tyrosine phosphorylation; WIP; WIPF1

Indexed keywords

BRUTON TYROSINE KINASE; DASATINIB; NEURAL WISKOTT ALDRICH SYNDROME PROTEIN; PROTEIN TYROSINE KINASE; TYROSINE; UNCLASSIFIED DRUG; WIP PROTEIN; AGAMMAGLOBULINAEMIA TYROSINE KINASE; CYTOSKELETON PROTEIN; PROTEIN BINDING; SIGNAL PEPTIDE; WIPF1 PROTEIN, HUMAN; WISKOTT ALDRICH SYNDROME PROTEIN;

ARTICLE; CELL ADHESION; CELL FUNCTION; CELL MIGRATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; MACROPHAGE; MONOCYTE; PODOSOME; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; ACTIN FILAMENT; ANIMAL; EXTRACELLULAR MATRIX; GENETICS; METABOLISM; PHOSPHORYLATION;

ACTIN CYTOSKELETON; ANIMALS; CYTOSKELETAL PROTEINS; EXTRACELLULAR MATRIX; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MACROPHAGES; PHOSPHORYLATION; PODOSOMES; PROTEIN BINDING; PROTEIN-TYROSINE KINASES; TYROSINE; WISKOTT-ALDRICH SYNDROME PROTEIN;

EID: 84921342057     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.154880     Document Type: Article

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