Critical roles of the WASP N-terminal domain and Btk in LPS-induced inflammatory response in macrophages

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Sakuma, Chisato ^a,b   Sato, Mitsuru ^a   Takenouchi, Takato ^a   Chiba, Joe ^b   Kitani, Hiroshi ^a  

^a NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BRUTON TYROSINE KINASE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12P40; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PROTEIN SH3; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; TYROSINE; WISKOTT ALDRICH SYNDROME PROTEIN; AGAMMAGLOBULINAEMIA TYROSINE KINASE; CARRIER PROTEIN; INTERLEUKIN 1 RECEPTOR; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE; TIRAP PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 4; WASPIP PROTEIN, MOUSE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXON; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT; SRC HOMOLOGY DOMAIN; TRANSGENIC MOUSE; ANIMAL; BIOSYNTHESIS; BONE MARROW CELL; C57BL MOUSE; CELL LINE; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

MUS MUSCULUS;

ANIMALS; BONE MARROW CELLS; CARRIER PROTEINS; CELL LINE; ENZYME ACTIVATION; INFLAMMATION; INTERFERON-GAMMA; LIPOPOLYSACCHARIDES; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NF-KAPPA B; NITRIC OXIDE; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; RECEPTORS, INTERLEUKIN-1; STRUCTURE-ACTIVITY RELATIONSHIP; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA; WISKOTT-ALDRICH SYNDROME PROTEIN;

EID: 84855813364     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030351     Document Type: Article

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