-
1
-
-
78149435915
-
Bypass mechanisms of the androgen receptor pathway in therapy-resistant prostate cancer cell models
-
Marques RB, Dits NF, Erkens-Schulze S, van Weerden WM, Jenster G. Bypass mechanisms of the androgen receptor pathway in therapy-resistant prostate cancer cell models. PloS one. 2010; 5:e13500.
-
(2010)
PloS one.
, vol.5
-
-
Marques, R.B.1
Dits, N.F.2
Erkens-Schulze, S.3
van Weerden, W.M.4
Jenster, G.5
-
2
-
-
60149089419
-
Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion
-
Harris WP, Mostaghel EA, Nelson PS, Montgomery B. Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion. Nature clinical practice Urology. 2009; 6:76-85.
-
(2009)
Nature clinical practice Urology.
, vol.6
, pp. 76-85
-
-
Harris, W.P.1
Mostaghel, E.A.2
Nelson, P.S.3
Montgomery, B.4
-
4
-
-
49249119358
-
Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth
-
Montgomery RB, Mostaghel EA, Vessella R, Hess DL, Kalhorn TF, Higano CS, True LD, Nelson PS. Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer research. 2008; 68:4447-4454.
-
(2008)
Cancer research.
, vol.68
, pp. 4447-4454
-
-
Montgomery, R.B.1
Mostaghel, E.A.2
Vessella, R.3
Hess, D.L.4
Kalhorn, T.F.5
Higano, C.S.6
True, L.D.7
Nelson, P.S.8
-
5
-
-
51049098138
-
Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
-
Locke JA, Guns ES, Lubik AA, Adomat HH, Hendy SC, Wood CA, Ettinger SL, Gleave ME, Nelson CC. Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. Cancer research. 2008; 68:6407-6415.
-
(2008)
Cancer research.
, vol.68
, pp. 6407-6415
-
-
Locke, J.A.1
Guns, E.S.2
Lubik, A.A.3
Adomat, H.H.4
Hendy, S.C.5
Wood, C.A.6
Ettinger, S.L.7
Gleave, M.E.8
Nelson, C.C.9
-
6
-
-
34250331066
-
Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer
-
Mostaghel EA, Page ST, Lin DW, Fazli L, Coleman IM, True LD, Knudsen B, Hess DL, Nelson CC, Matsumoto AM, Bremner WJ, Gleave ME, Nelson PS. Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer. Cancer research. 2007; 67:5033-5041.
-
(2007)
Cancer research.
, vol.67
, pp. 5033-5041
-
-
Mostaghel, E.A.1
Page, S.T.2
Lin, D.W.3
Fazli, L.4
Coleman, I.M.5
True, L.D.6
Knudsen, B.7
Hess, D.L.8
Nelson, C.C.9
Matsumoto, A.M.10
Bremner, W.J.11
Gleave, M.E.12
Nelson, P.S.13
-
7
-
-
33645056171
-
Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer
-
Stanbrough M, Bubley GJ, Ross K, Golub TR, Rubin MA, Penning TM, Febbo PG, Balk SP. Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer. Cancer research. 2006; 66:2815-2825.
-
(2006)
Cancer research.
, vol.66
, pp. 2815-2825
-
-
Stanbrough, M.1
Bubley, G.J.2
Ross, K.3
Golub, T.R.4
Rubin, M.A.5
Penning, T.M.6
Febbo, P.G.7
Balk, S.P.8
-
8
-
-
34247576131
-
An androgen-IL-6-Stat3 autocrine loop re-routes EGF signal in prostate cancer cells
-
Aaronson DS, Muller M, Neves SR, Chung WC, Jayaram G, Iyengar R, Ram PT. An androgen-IL-6-Stat3 autocrine loop re-routes EGF signal in prostate cancer cells. Molecular and cellular endocrinology. 2007; 270:50-56.
-
(2007)
Molecular and cellular endocrinology.
, vol.270
, pp. 50-56
-
-
Aaronson, D.S.1
Muller, M.2
Neves, S.R.3
Chung, W.C.4
Jayaram, G.5
Iyengar, R.6
Ram, P.T.7
-
9
-
-
33748927940
-
Interaction of IGF signaling and the androgen receptor in prostate cancer progression
-
Wu JD, Haugk K, Woodke L, Nelson P, Coleman I, Plymate SR. Interaction of IGF signaling and the androgen receptor in prostate cancer progression. Journal of cellular biochemistry. 2006; 99:392-401.
-
(2006)
Journal of cellular biochemistry.
, vol.99
, pp. 392-401
-
-
Wu, J.D.1
Haugk, K.2
Woodke, L.3
Nelson, P.4
Coleman, I.5
Plymate, S.R.6
-
10
-
-
81255150464
-
Androgen receptor variants occur frequently in castration resistant prostate cancer metastases
-
Zhang X, Morrissey C, Sun S, Ketchandji M, Nelson PS, True LD, Vakar-Lopez F, Vessella RL, Plymate SR. Androgen receptor variants occur frequently in castration resistant prostate cancer metastases. PloS one. 2011; 6:e27970.
-
(2011)
PloS one.
, vol.6
-
-
Zhang, X.1
Morrissey, C.2
Sun, S.3
Ketchandji, M.4
Nelson, P.S.5
True, L.D.6
Vakar-Lopez, F.7
Vessella, R.L.8
Plymate, S.R.9
-
11
-
-
84876695259
-
Androgen receptor splice variants are resistant to inhibitors of Hsp90 and FKBP52, which alter androgen receptor activity and expression
-
Shafi AA, Cox MB, Weigel NL. Androgen receptor splice variants are resistant to inhibitors of Hsp90 and FKBP52, which alter androgen receptor activity and expression. Steroids. 2013.
-
(2013)
Steroids
-
-
Shafi, A.A.1
Cox, M.B.2
Weigel, N.L.3
-
12
-
-
80054931284
-
Alternatively spliced androgen receptor variants
-
Dehm SM, Tindall DJ. Alternatively spliced androgen receptor variants. Endocrine-related cancer. 2011; 18: R183-196.
-
(2011)
Endocrine-related cancer.
, vol.18
, pp. R183-R196
-
-
Dehm, S.M.1
Tindall, D.J.2
-
13
-
-
79961013987
-
A new trick of an old molecule: androgen receptor splice variants taking the stage?!
-
Guo Z, Qiu Y. A new trick of an old molecule: androgen receptor splice variants taking the stage?! International journal of biological sciences. 2011; 7:815-822.
-
(2011)
International journal of biological sciences
, vol.7
, pp. 815-822
-
-
Guo, Z.1
Qiu, Y.2
-
14
-
-
79959312739
-
A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities
-
Hu R, Isaacs WB, Luo J. A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities. The Prostate. 2011; 71:1656-1667.
-
(2011)
The Prostate.
, vol.71
, pp. 1656-1667
-
-
Hu, R.1
Isaacs, W.B.2
Luo, J.3
-
15
-
-
84907057471
-
AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer
-
Antonarakis ES, Lu C, Wang H, Luber B, Nakazawa M, Roeser JC, Chen Y, Mohammad TA, Fedor HL, Lotan TL, Zheng Q, De Marzo AM, Isaacs JT, Isaacs WB, Nadal R, Paller CJ, et al. AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer. The New England journal of medicine. 2014; 371:1028-1038.
-
(2014)
The New England journal of medicine.
, vol.371
, pp. 1028-1038
-
-
Antonarakis, E.S.1
Lu, C.2
Wang, H.3
Luber, B.4
Nakazawa, M.5
Roeser, J.C.6
Chen, Y.7
Mohammad, T.A.8
Fedor, H.L.9
Lotan, T.L.10
Zheng, Q.11
De Marzo, A.M.12
Isaacs, J.T.13
Isaacs, W.B.14
Nadal, R.15
Paller, C.J.16
-
16
-
-
65549168746
-
A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth
-
Guo Z, Yang X, Sun F, Jiang R, Linn DE, Chen H, Kong X, Melamed J, Tepper CG, Kung HJ, Brodie AM, Edwards J, Qiu Y. A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer research. 2009; 69:2305-2313.
-
(2009)
Cancer research.
, vol.69
, pp. 2305-2313
-
-
Guo, Z.1
Yang, X.2
Sun, F.3
Jiang, R.4
Linn, D.E.5
Chen, H.6
Kong, X.7
Melamed, J.8
Tepper, C.G.9
Kung, H.J.10
Brodie, A.M.11
Edwards, J.12
Qiu, Y.13
-
17
-
-
58249110391
-
Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer
-
Hu R, Dunn TA, Wei S, Isharwal S, Veltri RW, Humphreys E, Han M, Partin AW, Vessella RL, Isaacs WB, Bova GS, Luo J. Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer. Cancer research. 2009; 69:16-22.
-
(2009)
Cancer research.
, vol.69
, pp. 16-22
-
-
Hu, R.1
Dunn, T.A.2
Wei, S.3
Isharwal, S.4
Veltri, R.W.5
Humphreys, E.6
Han, M.7
Partin, A.W.8
Vessella, R.L.9
Isaacs, W.B.10
Bova, G.S.11
Luo, J.12
-
18
-
-
79955719838
-
Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival
-
Hornberg E, Ylitalo EB, Crnalic S, Antti H, Stattin P, Widmark A, Bergh A, Wikstrom P. Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival. PloS one. 2011; 6:e19059.
-
(2011)
PloS one.
, vol.6
-
-
Hornberg, E.1
Ylitalo, E.B.2
Crnalic, S.3
Antti, H.4
Stattin, P.5
Widmark, A.6
Bergh, A.7
Wikstrom, P.8
-
19
-
-
77955296562
-
Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
-
Sun S, Sprenger CC, Vessella RL, Haugk K, Soriano K, Mostaghel EA, Page ST, Coleman IM, Nguyen HM, Sun H, Nelson PS, Plymate SR. Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant. The Journal of clinical investigation. 2010; 120:2715-2730.
-
(2010)
The Journal of clinical investigation.
, vol.120
, pp. 2715-2730
-
-
Sun, S.1
Sprenger, C.C.2
Vessella, R.L.3
Haugk, K.4
Soriano, K.5
Mostaghel, E.A.6
Page, S.T.7
Coleman, I.M.8
Nguyen, H.M.9
Sun, H.10
Nelson, P.S.11
Plymate, S.R.12
-
20
-
-
84921412723
-
Androgen receptor splice variant AR3 promotes prostate cancer via modulating expression of autocrine/ paracrine factors
-
Sun F, Chen HG, Li W, Yang X, Wang X, Jiang R, Guo Z, Chen H, Huang J, Borowsky AD, Qiu Y. Androgen receptor splice variant AR3 promotes prostate cancer via modulating expression of autocrine/ paracrine factors. The Journal of biological chemistry. 2013.
-
(2013)
The Journal of biological chemistry
-
-
Sun, F.1
Chen, H.G.2
Li, W.3
Yang, X.4
Wang, X.5
Jiang, R.6
Guo, Z.7
Chen, H.8
Huang, J.9
Borowsky, A.D.10
Qiu, Y.11
-
21
-
-
84884377857
-
v567es induces carcinogenesis in a novel transgenic mouse model of prostate cancer
-
v567es induces carcinogenesis in a novel transgenic mouse model of prostate cancer. Neoplasia. 2013; 15:1009-1017.
-
(2013)
Neoplasia.
, vol.15
, pp. 1009-1017
-
-
Liu, G.1
Sprenger, C.2
Sun, S.3
Epilepsia, K.S.4
Haugk, K.5
Zhang, X.6
Coleman, I.7
Nelson, P.S.8
Plymate, S.9
-
22
-
-
84863979005
-
Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer
-
Hu R, Lu C, Mostaghel EA, Yegnasubramanian S, Gurel M, Tannahill C, Edwards J, Isaacs WB, Nelson PS, Bluemn E, Plymate SR, Luo J. Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer. Cancer research. 2012; 72:3457-3462.
-
(2012)
Cancer research.
, vol.72
, pp. 3457-3462
-
-
Hu, R.1
Lu, C.2
Mostaghel, E.A.3
Yegnasubramanian, S.4
Gurel, M.5
Tannahill, C.6
Edwards, J.7
Isaacs, W.B.8
Nelson, P.S.9
Bluemn, E.10
Plymate, S.R.11
Luo, J.12
-
23
-
-
67650758019
-
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer
-
Wang Q, Li W, Zhang Y, Yuan X, Xu K, Yu J, Chen Z, Beroukhim R, Wang H, Lupien M, Wu T, Regan MM, Meyer CA, Carroll JS, Manrai AK, Janne OA, et al. Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell. 2009; 138:245-256.
-
(2009)
Cell.
, vol.138
, pp. 245-256
-
-
Wang, Q.1
Li, W.2
Zhang, Y.3
Yuan, X.4
Xu, K.5
Yu, J.6
Chen, Z.7
Beroukhim, R.8
Wang, H.9
Lupien, M.10
Wu, T.11
Regan, M.M.12
Meyer, C.A.13
Carroll, J.S.14
Manrai, A.K.15
Janne, O.A.16
-
24
-
-
33845573384
-
Expression and effect of inhibition of the ubiquitin-conjugating enzyme E2C on esophageal adenocarcinoma
-
Lin J, Raoof DA, Wang Z, Lin MY, Thomas DG, Greenson JK, Giordano TJ, Orringer MB, Chang AC, Beer DG, Lin L. Expression and effect of inhibition of the ubiquitin-conjugating enzyme E2C on esophageal adenocarcinoma. Neoplasia. 2006; 8:1062-1071.
-
(2006)
Neoplasia.
, vol.8
, pp. 1062-1071
-
-
Lin, J.1
Raoof, D.A.2
Wang, Z.3
Lin, M.Y.4
Thomas, D.G.5
Greenson, J.K.6
Giordano, T.J.7
Orringer, M.B.8
Chang, A.C.9
Beer, D.G.10
Lin, L.11
-
25
-
-
24944545733
-
UbcH10 overexpression may represent a marker of anaplastic thyroid carcinomas
-
Pallante P, Berlingieri MT, Troncone G, Kruhoffer M, Orntoft TF, Viglietto G, Caleo A, Migliaccio I, Decaussin-Petrucci M, Santoro M, Palombini L, Fusco A. UbcH10 overexpression may represent a marker of anaplastic thyroid carcinomas. British journal of cancer. 2005; 93: 464-471.
-
(2005)
British journal of cancer.
, vol.93
, pp. 464-471
-
-
Pallante, P.1
Berlingieri, M.T.2
Troncone, G.3
Kruhoffer, M.4
Orntoft, T.F.5
Viglietto, G.6
Caleo, A.7
Migliaccio, I.8
Decaussin-Petrucci, M.9
Santoro, M.10
Palombini, L.11
Fusco, A.12
-
26
-
-
4444229048
-
Overexpression, genomic amplification and therapeutic potential of inhibiting the UbcH10 ubiquitin conjugase in human carcinomas of diverse anatomic origin
-
Wagner KW, Sapinoso LM, El-Rifai W, Frierson HF, Butz N, Mestan J, Hofmann F, Deveraux QL, Hampton GM. Overexpression, genomic amplification and therapeutic potential of inhibiting the UbcH10 ubiquitin conjugase in human carcinomas of diverse anatomic origin. Oncogene. 2004; 23:6621-6629.
-
(2004)
Oncogene.
, vol.23
, pp. 6621-6629
-
-
Wagner, K.W.1
Sapinoso, L.M.2
El-Rifai, W.3
Frierson, H.F.4
Butz, N.5
Mestan, J.6
Hofmann, F.7
Deveraux, Q.L.8
Hampton, G.M.9
-
27
-
-
27644506613
-
Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression
-
Varambally S, Yu J, Laxman B, Rhodes DR, Mehra R, Tomlins SA, Shah RB, Chandran U, Monzon FA, Becich MJ, Wei JT, Pienta KJ, Ghosh D, Rubin MA, Chinnaiyan AM. Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression. Cancer cell. 2005; 8:393-406.
-
(2005)
Cancer cell.
, vol.8
, pp. 393-406
-
-
Varambally, S.1
Yu, J.2
Laxman, B.3
Rhodes, D.R.4
Mehra, R.5
Tomlins, S.A.6
Shah, R.B.7
Chandran, U.8
Monzon, F.A.9
Becich, M.J.10
Wei, J.T.11
Pienta, K.J.12
Ghosh, D.13
Rubin, M.A.14
Chinnaiyan, A.M.15
-
28
-
-
58049196759
-
Mechanisms mediating androgen receptor reactivation after castration
-
Yuan X, Balk SP. Mechanisms mediating androgen receptor reactivation after castration. Urologic oncology. 2009; 27:36-41.
-
(2009)
Urologic oncology.
, vol.27
, pp. 36-41
-
-
Yuan, X.1
Balk, S.P.2
-
29
-
-
0036219918
-
Androgen receptor (AR) coregulators: an overview
-
Heinlein CA, Chang C. Androgen receptor (AR) coregulators: an overview. Endocrine reviews. 2002; 23:175-200.
-
(2002)
Endocrine reviews.
, vol.23
, pp. 175-200
-
-
Heinlein, C.A.1
Chang, C.2
-
32
-
-
84856937196
-
FOXA1: a transcription factor with parallel functions in development and cancer
-
Bernardo GM, Keri RA. FOXA1: a transcription factor with parallel functions in development and cancer. Bioscience reports. 2012; 32:113-130.
-
(2012)
Bioscience reports.
, vol.32
, pp. 113-130
-
-
Bernardo, G.M.1
Keri, R.A.2
-
33
-
-
34249327738
-
A coregulatory role for the mediator complex in prostate cancer cell proliferation and gene expression
-
Vijayvargia R, May MS, Fondell JD. A coregulatory role for the mediator complex in prostate cancer cell proliferation and gene expression. Cancer research. 2007; 67:4034-4041.
-
(2007)
Cancer research.
, vol.67
, pp. 4034-4041
-
-
Vijayvargia, R.1
May, M.S.2
Fondell, J.D.3
-
34
-
-
84872808630
-
The activity of the androgen receptor variant AR-V7 is regulated by FOXO1 in a PTEN-PI3K-AKTdependent way
-
Mediwala SN, Sun H, Szafran AT, Hartig SM, Sonpavde G, Hayes TG, Thiagarajan P, Mancini MA, Marcelli M. The activity of the androgen receptor variant AR-V7 is regulated by FOXO1 in a PTEN-PI3K-AKTdependent way. The Prostate. 2013; 73:267-277.
-
(2013)
The Prostate.
, vol.73
, pp. 267-277
-
-
Mediwala, S.N.1
Sun, H.2
Szafran, A.T.3
Hartig, S.M.4
Sonpavde, G.5
Hayes, T.G.6
Thiagarajan, P.7
Mancini, M.A.8
Marcelli, M.9
-
35
-
-
79958864543
-
Phospho-MED1-enhanced UBE2C locus looping drives castration-resistant prostate cancer growth
-
Chen Z, Zhang C, Wu D, Chen H, Rorick A, Zhang X, Wang Q. Phospho-MED1-enhanced UBE2C locus looping drives castration-resistant prostate cancer growth. The EMBO journal. 2011; 30:2405-2419.
-
(2011)
The EMBO journal.
, vol.30
, pp. 2405-2419
-
-
Chen, Z.1
Zhang, C.2
Wu, D.3
Chen, H.4
Rorick, A.5
Zhang, X.6
Wang, Q.7
-
36
-
-
77952105685
-
Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1-2 study
-
Scher HI, Beer TM, Higano CS, Anand A, Taplin ME, Efstathiou E, Rathkopf D, Shelkey J, Yu EY, Alumkal J, Hung D, Hirmand M, Seely L, Morris MJ, Danila DC, Humm J, et al. Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1-2 study. Lancet. 2010; 375:1437-1446.
-
(2010)
Lancet.
, vol.375
, pp. 1437-1446
-
-
Scher, H.I.1
Beer, T.M.2
Higano, C.S.3
Anand, A.4
Taplin, M.E.5
Efstathiou, E.6
Rathkopf, D.7
Shelkey, J.8
Yu, E.Y.9
Alumkal, J.10
Hung, D.11
Hirmand, M.12
Seely, L.13
Morris, M.J.14
Danila, D.C.15
Humm, J.16
-
37
-
-
77954255681
-
Integrative genomic profiling of human prostate cancer
-
Taylor BS, Schultz N, Hieronymus H, Gopalan A, Xiao Y, Carver BS, Arora VK, Kaushik P, Cerami E, Reva B, Antipin Y, Mitsiades N, Landers T, Dolgalev I, Major JE, Wilson M, et al. Integrative genomic profiling of human prostate cancer. Cancer cell. 2010; 18:11-22.
-
(2010)
Cancer cell.
, vol.18
, pp. 11-22
-
-
Taylor, B.S.1
Schultz, N.2
Hieronymus, H.3
Gopalan, A.4
Xiao, Y.5
Carver, B.S.6
Arora, V.K.7
Kaushik, P.8
Cerami, E.9
Reva, B.10
Antipin, Y.11
Mitsiades, N.12
Landers, T.13
Dolgalev, I.14
Major, J.E.15
Wilson, M.16
-
38
-
-
0033214780
-
Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins
-
Hittelman AB, Burakov D, Iniguez-Lluhi JA, Freedman LP, Garabedian MJ. Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins. The EMBO journal. 1999; 18:5380-5388.
-
(1999)
The EMBO journal.
, vol.18
, pp. 5380-5388
-
-
Hittelman, A.B.1
Burakov, D.2
Iniguez-Lluhi, J.A.3
Freedman, L.P.4
Garabedian, M.J.5
-
39
-
-
13044271699
-
Amplification and overexpression of peroxisome proliferator-activated receptor binding protein (PBP/PPARBP) gene in breast cancer.
-
Zhu Y, Qi C, Jain S, Le Beau MM, Espinosa R. 3rd, Atkins GB, Lazar MA, Yeldandi AV, Rao MS, Reddy JK. Amplification and overexpression of peroxisome proliferator-activated receptor binding protein (PBP/PPARBP) gene in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 1999; 96:10848-10853.
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America.
, vol.96
, pp. 10848-10853
-
-
Zhu, Y.1
Qi, C.2
Jain, S.3
Le Beau, M.M.4
Espinosa, R.5
Atkins, G.B.6
Lazar, M.A.7
Yeldandi, A.V.8
Rao, M.S.9
Reddy, J.K.10
-
40
-
-
0033525687
-
Competition between thyroid hormone receptor-associated protein (TRAP) 220 and transcriptional intermediary factor (TIF) 2 for binding to nuclear receptors Implications for the recruitment of TRAP and p160 coactivator complexes.
-
Treuter E, Johansson L, Thomsen JS, Warnmark A, Leers J, Pelto-Huikko M, Sjoberg M, Wright AP, Spyrou G, Gustafsson JA. Competition between thyroid hormone receptor-associated protein (TRAP) 220 and transcriptional intermediary factor (TIF) 2 for binding to nuclear receptors. Implications for the recruitment of TRAP and p160 coactivator complexes. The Journal of biological chemistry. 1999; 274:6667-6677.
-
(1999)
The Journal of biological chemistry.
, vol.274
, pp. 6667-6677
-
-
Treuter, E.1
Johansson, L.2
Thomsen, J.S.3
Warnmark, A.4
Leers, J.5
Pelto-Huikko, M.6
Sjoberg, M.7
Wright, A.P.8
Spyrou, G.9
Gustafsson, J.A.10
-
41
-
-
0037044767
-
A coregulatory role for the TRAP-mediator complex in androgen receptormediated gene expression
-
Wang Q, Sharma D, Ren Y, Fondell JD. A coregulatory role for the TRAP-mediator complex in androgen receptormediated gene expression. The Journal of biological chemistry. 2002; 277:42852-42858.
-
(2002)
The Journal of biological chemistry.
, vol.277
, pp. 42852-42858
-
-
Wang, Q.1
Sharma, D.2
Ren, Y.3
Fondell, J.D.4
-
42
-
-
84880539068
-
ERK and AKT signaling drive MED1 overexpression in prostate cancer in association with elevated proliferation and tumorigenicity
-
Jin F, Irshad S, Yu W, Belakavadi M, Chekmareva M, Ittmann MM, Abate-Shen C, Fondell JD. ERK and AKT signaling drive MED1 overexpression in prostate cancer in association with elevated proliferation and tumorigenicity. Molecular cancer research: MCR. 2013; 11:736-747.
-
(2013)
Molecular cancer research: MCR.
, vol.11
, pp. 736-747
-
-
Jin, F.1
Irshad, S.2
Yu, W.3
Belakavadi, M.4
Chekmareva, M.5
Ittmann, M.M.6
Abate-Shen, C.7
Fondell, J.D.8
-
43
-
-
84855488177
-
Regulation of androgen receptor-dependent transcription by coactivator MED1 is mediated through a newly discovered noncanonical binding motif
-
Jin F, Claessens F, Fondell JD. Regulation of androgen receptor-dependent transcription by coactivator MED1 is mediated through a newly discovered noncanonical binding motif. The Journal of biological chemistry. 2012; 287:858-870.
-
(2012)
The Journal of biological chemistry.
, vol.287
, pp. 858-870
-
-
Jin, F.1
Claessens, F.2
Fondell, J.D.3
-
44
-
-
84868228009
-
Cross-talk between HER2 and MED1 regulates tamoxifen resistance of human breast cancer cells
-
Cui J, Germer K, Wu T, Wang J, Luo J, Wang SC, Wang Q, Zhang X. Cross-talk between HER2 and MED1 regulates tamoxifen resistance of human breast cancer cells. Cancer research. 2012; 72:5625-5634.
-
(2012)
Cancer research.
, vol.72
, pp. 5625-5634
-
-
Cui, J.1
Germer, K.2
Wu, T.3
Wang, J.4
Luo, J.5
Wang, S.C.6
Wang, Q.7
Zhang, X.8
-
45
-
-
2242451441
-
Phosphorylation of transcriptional coactivator peroxisome proliferatoractivated receptor (PPAR)-binding protein (PBP) Stimulation of transcriptional regulation by mitogen-activated protein kinase.
-
Misra P, Owuor ED, Li W, Yu S, Qi C, Meyer K, Zhu YJ, Rao MS, Kong AN, Reddy JK. Phosphorylation of transcriptional coactivator peroxisome proliferatoractivated receptor (PPAR)-binding protein (PBP). Stimulation of transcriptional regulation by mitogen-activated protein kinase. The Journal of biological chemistry. 2002; 277:48745-48754.
-
(2002)
The Journal of biological chemistry.
, vol.277
, pp. 48745-48754
-
-
Misra, P.1
Owuor, E.D.2
Li, W.3
Yu, S.4
Qi, C.5
Meyer, K.6
Zhu, Y.J.7
Rao, M.S.8
Kong, A.N.9
Reddy, J.K.10
-
46
-
-
28544440730
-
Activation of TRAP/mediator subunit TRAP220/Med1 is regulated by mitogen-activated protein kinase-dependent phosphorylation
-
Pandey PK, Udayakumar TS, Lin X, Sharma D, Shapiro PS, Fondell JD. Activation of TRAP/mediator subunit TRAP220/Med1 is regulated by mitogen-activated protein kinase-dependent phosphorylation. Molecular and cellular biology. 2005; 25:10695-10710.
-
(2005)
Molecular and cellular biology.
, vol.25
, pp. 10695-10710
-
-
Pandey, P.K.1
Udayakumar, T.S.2
Lin, X.3
Sharma, D.4
Shapiro, P.S.5
Fondell, J.D.6
-
47
-
-
84884804685
-
The Med1 Subunit of the Mediator Complex Induces Liver Cell Proliferation and Is Phosphorylated by AMP Kinase
-
Viswakarma N, Jia Y, Bai L, Gao Q, Lin B, Zhang X, Misra P, Rana A, Jain S, Gonzalez FJ, Zhu YJ, Thimmapaya B, Reddy JK. The Med1 Subunit of the Mediator Complex Induces Liver Cell Proliferation and Is Phosphorylated by AMP Kinase. The Journal of biological chemistry. 2013; 288:27898-27911.
-
(2013)
The Journal of biological chemistry.
, vol.288
, pp. 27898-27911
-
-
Viswakarma, N.1
Jia, Y.2
Bai, L.3
Gao, Q.4
Lin, B.5
Zhang, X.6
Misra, P.7
Rana, A.8
Jain, S.9
Gonzalez, F.J.10
Zhu, Y.J.11
Thimmapaya, B.12
Reddy, J.K.13
-
48
-
-
27844506524
-
Akt-regulated pathways in prostate cancer
-
Majumder PK, Sellers WR. Akt-regulated pathways in prostate cancer. Oncogene. 2005; 24:7465-7474.
-
(2005)
Oncogene.
, vol.24
, pp. 7465-7474
-
-
Majumder, P.K.1
Sellers, W.R.2
-
50
-
-
0029913708
-
Cytogenetic characterization of the human prostate cancer cell line P69SV40T and its novel tumorigenic sublines M2182 and M15
-
Jackson-Cook C, Bae V, Edelman W, Brothman A, Ware J. Cytogenetic characterization of the human prostate cancer cell line P69SV40T and its novel tumorigenic sublines M2182 and M15. Cancer genetics and cytogenetics. 1996; 87:14-23.
-
(1996)
Cancer genetics and cytogenetics.
, vol.87
, pp. 14-23
-
-
Jackson-Cook, C.1
Bae, V.2
Edelman, W.3
Brothman, A.4
Ware, J.5
-
51
-
-
0029819826
-
The effect on the insulin-like growth factor system in human prostate epithelial cells of immortalization and transformation by simian virus-40 T antigen
-
Plymate SR, Tennant M, Birnbaum RS, Thrasher JB, Chatta G, Ware JL. The effect on the insulin-like growth factor system in human prostate epithelial cells of immortalization and transformation by simian virus-40 T antigen. The Journal of clinical endocrinology and metabolism. 1996; 81:3709-3716.
-
(1996)
The Journal of clinical endocrinology and metabolism.
, vol.81
, pp. 3709-3716
-
-
Plymate, S.R.1
Tennant, M.2
Birnbaum, R.S.3
Thrasher, J.B.4
Chatta, G.5
Ware, J.L.6
-
52
-
-
0031944186
-
Metastatic sublines of an SV40 large T antigen immortalized human prostate epithelial cell line
-
Bae VL, Jackson-Cook CK, Maygarden SJ, Plymate SR, Chen J, Ware JL. Metastatic sublines of an SV40 large T antigen immortalized human prostate epithelial cell line. The Prostate. 1998; 34:275-282.
-
(1998)
The Prostate.
, vol.34
, pp. 275-282
-
-
Bae, V.L.1
Jackson-Cook, C.K.2
Maygarden, S.J.3
Plymate, S.R.4
Chen, J.5
Ware, J.L.6
-
53
-
-
5344261144
-
Androgen receptor (AR) expression in AR-negative prostate cancer cells results in differential effects of DHT and IGF-I on proliferation and AR activity between localized and metastatic tumors.
-
Plymate SR, Tennant MK, Culp SH, Woodke L, Marcelli M, Colman I, Nelson PS, Carroll JM, Roberts CT. Jr., Ware JL. Androgen receptor (AR) expression in AR-negative prostate cancer cells results in differential effects of DHT and IGF-I on proliferation and AR activity between localized and metastatic tumors. The Prostate. 2004; 61:276-290.
-
(2004)
The Prostate.
, vol.61
, pp. 276-290
-
-
Plymate, S.R.1
Tennant, M.K.2
Culp, S.H.3
Woodke, L.4
Marcelli, M.5
Colman, I.6
Nelson, P.S.7
Carroll, J.M.8
Roberts, C.T.9
Ware, J.L.10
-
54
-
-
0023742799
-
GAL4 derivatives function alone and synergistically with mammalian activators in vitro
-
Lin YS, Carey MF, Ptashne M, Green MR. GAL4 derivatives function alone and synergistically with mammalian activators in vitro. Cell. 1988; 54:659-664.
-
(1988)
Cell.
, vol.54
, pp. 659-664
-
-
Lin, Y.S.1
Carey, M.F.2
Ptashne, M.3
Green, M.R.4
-
55
-
-
34547931715
-
Cell-and gene-specific regulation of primary target genes by the androgen receptor
-
Bolton EC, So AY, Chaivorapol C, Haqq CM, Li H, Yamamoto KR. Cell-and gene-specific regulation of primary target genes by the androgen receptor. Genes & development. 2007; 21:2005-2017.
-
(2007)
Genes & development.
, vol.21
, pp. 2005-2017
-
-
Bolton, E.C.1
So, A.Y.2
Chaivorapol, C.3
Haqq, C.M.4
Li, H.5
Yamamoto, K.R.6
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