-
1
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA Cancer J Clin. 2010; 60: 277-300.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
2
-
-
0041342078
-
Factors that mediate and modulate androgen action
-
Mc-Phaul MJ. Factors that mediate and modulate androgen action. J Investig Dermatol Symp Proc. 2003; 8: 1-5.
-
(2003)
J Investig Dermatol Symp Proc
, vol.8
, pp. 1-5
-
-
Mc-Phaul, M.J.1
-
3
-
-
2342558431
-
Androgen receptor in prostate cancer
-
Heinlein CA, Chang C. Androgen receptor in prostate cancer. Endocr Rev. 2004; 25: 276-308.
-
(2004)
Endocr Rev
, vol.25
, pp. 276-308
-
-
Heinlein, C.A.1
Chang, C.2
-
4
-
-
0033304531
-
Hormonal signaling in prostatic hyperplasia and neoplasia
-
Marcelli M, Cunningham GR. Hormonal signaling in prostatic hyperplasia and neoplasia. J Clin Endocrinol Metab. 1999; 84: 3463-8.
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 3463-3468
-
-
Marcelli, M.1
Cunningham, G.R.2
-
5
-
-
0033838227
-
Androgen receptor--an update of mechanisms of action in prostate cancer
-
Culig Z, Hobisch A, Bartsch G, Klocker H. Androgen receptor--an update of mechanisms of action in prostate cancer. Urol Res. 2000; 28: 211-9.
-
(2000)
Urol Res
, vol.28
, pp. 211-219
-
-
Culig, Z.1
Hobisch, A.2
Bartsch, G.3
Klocker, H.4
-
6
-
-
1842612441
-
Molecular determinants of resistance to antiandrogen therapy
-
Chen CD, Welsbie DS, Tran C, Baek SH, Chen R, Vessella R, et al. Molecular determinants of resistance to antiandrogen therapy. Nat Med. 2004; 10: 33-9.
-
(2004)
Nat Med
, vol.10
, pp. 33-39
-
-
Chen, C.D.1
Welsbie, D.S.2
Tran, C.3
Baek, S.H.4
Chen, R.5
Vessella, R.6
-
7
-
-
0036170838
-
Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells
-
Zegarra-Moro OL, Schmidt LJ, Huang H, Tindall DJ. Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells. Cancer Res. 2002; 62: 1008-13.
-
(2002)
Cancer Res
, vol.62
, pp. 1008-1013
-
-
Zegarra-Moro, O.L.1
Schmidt, L.J.2
Huang, H.3
Tindall, D.J.4
-
9
-
-
0036645414
-
Molecular biology of the androgen receptor
-
Gelmann EP. Molecular biology of the androgen receptor. J Clin Oncol. 2002; 20: 3001-15.
-
(2002)
J Clin Oncol
, vol.20
, pp. 3001-3015
-
-
Gelmann, E.P.1
-
10
-
-
0035496220
-
The development of androgen-independent prostate cancer
-
Feldman BJ, Feldman D. The development of androgen-independent prostate cancer. Nat Rev Cancer. 2001; 1: 34-45.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 34-45
-
-
Feldman, B.J.1
Feldman, D.2
-
11
-
-
48549089747
-
Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance
-
Dehm SM, Schmidt LJ, Heemers HV, Vessella RL, Tindall DJ. Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance. Cancer Res. 2008; 68: 5469-77.
-
(2008)
Cancer Res
, vol.68
, pp. 5469-5477
-
-
Dehm, S.M.1
Schmidt, L.J.2
Heemers, H.V.3
Vessella, R.L.4
Tindall, D.J.5
-
12
-
-
65549168746
-
A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth
-
Guo Z, Yang X, Sun F, Jiang R, Linn DE, Chen H, et al. A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Res. 2009; 69: 2305-13.
-
(2009)
Cancer Res
, vol.69
, pp. 2305-2313
-
-
Guo, Z.1
Yang, X.2
Sun, F.3
Jiang, R.4
Linn, D.E.5
Chen, H.6
-
13
-
-
58249110391
-
Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer
-
Hu R, Dunn TA, Wei S, Isharwal S, Veltri RW, Humphreys E, et al. Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer. Cancer Res. 2009; 69: 16-22.
-
(2009)
Cancer Res
, vol.69
, pp. 16-22
-
-
Hu, R.1
Dunn, T.A.2
Wei, S.3
Isharwal, S.4
Veltri, R.W.5
Humphreys, E.6
-
14
-
-
77955296562
-
Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
-
Sun S, Sprenger CC, Vessella RL, Haugk K, Soriano K, Mostaghel EA, et al. Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant. J Clin Invest. 2010; 120: 2715-30.
-
(2010)
J Clin Invest
, vol.120
, pp. 2715-2730
-
-
Sun, S.1
Sprenger, C.C.2
Vessella, R.L.3
Haugk, K.4
Soriano, K.5
Mostaghel, E.A.6
-
15
-
-
78049280194
-
Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
-
Watson PA, Chen YF, Balbas MD, Wongvipat J, Socci ND, Viale A, et al. Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor. Proc Natl Acad Sci USA. 2010; 107: 16759-65.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 16759-16765
-
-
Watson, P.A.1
Chen, Y.F.2
Balbas, M.D.3
Wongvipat, J.4
Socci, N.D.5
Viale, A.6
-
16
-
-
0023929785
-
Molecular cloning of human and rat complementary DNA encoding androgen receptors
-
Chang CS, Kokontis J, Liao ST. Molecular cloning of human and rat complementary DNA encoding androgen receptors. Science. 1988; 240: 324-6.
-
(1988)
Science
, vol.240
, pp. 324-326
-
-
Chang, C.S.1
Kokontis, J.2
Liao, S.T.3
-
17
-
-
0023910355
-
Cloning of human androgen receptor complementary DNA and localization to the X chromosome
-
Lubahn DB, Joseph DR, Sullivan PM, Willard HF, French FS, Wilson EM. Cloning of human androgen receptor complementary DNA and localization to the X chromosome. Science. 1988; 240: 327-30.
-
(1988)
Science
, vol.240
, pp. 327-330
-
-
Lubahn, D.B.1
Joseph, D.R.2
Sullivan, P.M.3
Willard, H.F.4
French, F.S.5
Wilson, E.M.6
-
18
-
-
0025957233
-
Transcriptional activation and nuclear targeting signals of the human androgen receptor
-
Simental JA, Sar M, Lane MV, French FS, Wilson EM. Transcriptional activation and nuclear targeting signals of the human androgen receptor. J Biol Chem. 1991; 266: 510-8.
-
(1991)
J Biol Chem
, vol.266
, pp. 510-518
-
-
Simental, J.A.1
Sar, M.2
Lane, M.V.3
French, F.S.4
Wilson, E.M.5
-
19
-
-
0025935923
-
Domains of the human androgen receptor involved in steroid binding, transcriptional activation, and subcellular localization
-
Jenster G, van der Korput HA, van Vroonhoven C, van der Kwast TH, Trapman J, Brinkmann AO. Domains of the human androgen receptor involved in steroid binding, transcriptional activation, and subcellular localization. Mol Endocrinol. 1991; 5: 1396-404.
-
(1991)
Mol Endocrinol
, vol.5
, pp. 1396-1404
-
-
Jenster, G.1
van der Korput, H.A.2
van Vroonhoven, C.3
van der Kwast, T.H.4
Trapman, J.5
Brinkmann, A.O.6
-
20
-
-
0025039237
-
Functional characterizations of the androgen receptor confirm that the molecular basis of androgen action is transcriptional regulation
-
Rundlett SE, Wu XP, Miesfeld RL. Functional characterizations of the androgen receptor confirm that the molecular basis of androgen action is transcriptional regulation. Mol Endocrinol. 1990; 4: 708-14.
-
(1990)
Mol Endocrinol
, vol.4
, pp. 708-714
-
-
Rundlett, S.E.1
Wu, X.P.2
Miesfeld, R.L.3
-
21
-
-
0028014597
-
A and B forms of the androgen receptor are present in human genital skin fibroblasts
-
Wilson CM, McPhaul MJ. A and B forms of the androgen receptor are present in human genital skin fibroblasts. Proc Natl Acad Sci USA. 1994; 91: 1234-8.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 1234-1238
-
-
Wilson, C.M.1
McPhaul, M.J.2
-
22
-
-
0035199329
-
The putative androgen receptor-A form results from in vitro proteolysis
-
Gregory CW, He B, Wilson EM. The putative androgen receptor-A form results from in vitro proteolysis. J Mol Endocrinol. 2001; 27: 309-19.
-
(2001)
J Mol Endocrinol
, vol.27
, pp. 309-319
-
-
Gregory, C.W.1
He, B.2
Wilson, E.M.3
-
23
-
-
0037112372
-
Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line
-
Tepper CG, Boucher DL, Ryan PE, Ma AH, Xia L, Lee LF, et al. Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line. Cancer Res. 2002; 62: 6606-14.
-
(2002)
Cancer Res
, vol.62
, pp. 6606-6614
-
-
Tepper, C.G.1
Boucher, D.L.2
Ryan, P.E.3
Ma, A.H.4
Xia, L.5
Lee, L.F.6
-
24
-
-
35148833549
-
Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence
-
Libertini SJ, Tepper CG, Rodriguez V, Asmuth DM, Kung HJ, Mudryj M. Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence. Cancer Res. 2007; 67: 9001-5.
-
(2007)
Cancer Res
, vol.67
, pp. 9001-9005
-
-
Libertini, S.J.1
Tepper, C.G.2
Rodriguez, V.3
Asmuth, D.M.4
Kung, H.J.5
Mudryj, M.6
-
25
-
-
34548089696
-
Unexpected paracrine action of prostate cancer cells harboring a new class of androgen receptor mutation--a new paradigm for cooperation among prostate tumor cells
-
Lapouge G, Erdmann E, Marcias G, Jagla M, Monge A, Kessler P, et al. Unexpected paracrine action of prostate cancer cells harboring a new class of androgen receptor mutation--a new paradigm for cooperation among prostate tumor cells. Int J Cancer. 2007; 121: 1238-44.
-
(2007)
Int J Cancer
, vol.121
, pp. 1238-1244
-
-
Lapouge, G.1
Erdmann, E.2
Marcias, G.3
Jagla, M.4
Monge, A.5
Kessler, P.6
-
26
-
-
11444252143
-
Androgen receptor function is modulated by the tissue-specific AR45 variant
-
Ahrens-Fath I, Politz O, Geserick C, Haendler B. Androgen receptor function is modulated by the tissue-specific AR45 variant. FEBS J. 2005; 272: 74-84.
-
(2005)
FEBS J
, vol.272
, pp. 74-84
-
-
Ahrens-Fath, I.1
Politz, O.2
Geserick, C.3
Haendler, B.4
-
27
-
-
79955719838
-
Expression of Androgen Receptor Splice Variants in Prostate Cancer Bone Metastases is Associated with Castration-Resistance and Short Survival
-
Hornberg E, Ylitalo EB, Crnalic S, Antti H, Stattin P, Widmark A, et al. Expression of Androgen Receptor Splice Variants in Prostate Cancer Bone Metastases is Associated with Castration-Resistance and Short Survival. PLoS One. 2011; 6: e19059.
-
(2011)
PLoS One
, vol.6
-
-
Hornberg, E.1
Ylitalo, E.B.2
Crnalic, S.3
Antti, H.4
Stattin, P.5
Widmark, A.6
-
28
-
-
43149125406
-
Structural basis for the nuclear import of the human androgen receptor
-
Cutress ML, Whitaker HC, Mills IG, Stewart M, Neal DE. Structural basis for the nuclear import of the human androgen receptor. J Cell Sci. 2008; 121: 957-68.
-
(2008)
J Cell Sci
, vol.121
, pp. 957-968
-
-
Cutress, M.L.1
Whitaker, H.C.2
Mills, I.G.3
Stewart, M.4
Neal, D.E.5
-
29
-
-
0028225858
-
A ligand-dependent bipartite nuclear targeting signal in the human androgen receptor. Requirement for the DNA-binding domain and modulation by NH2-terminal and carboxyl-terminal sequences
-
Zhou ZX, Sar M, Simental JA, Lane MV, Wilson EM. A ligand-dependent bipartite nuclear targeting signal in the human androgen receptor. Requirement for the DNA-binding domain and modulation by NH2-terminal and carboxyl-terminal sequences. J Biol Chem. 1994; 269: 13115-23.
-
(1994)
J Biol Chem
, vol.269
, pp. 13115-13123
-
-
Zhou, Z.X.1
Sar, M.2
Simental, J.A.3
Lane, M.V.4
Wilson, E.M.5
-
30
-
-
33749445413
-
Regulation of androgen receptor activity by tyrosine phosphorylation
-
Guo Z, Dai B, Jiang T, Xu K, Xie Y, Kim O, et al. Regulation of androgen receptor activity by tyrosine phosphorylation. Cancer Cell. 2006; 10: 309-19.
-
(2006)
Cancer Cell
, vol.10
, pp. 309-319
-
-
Guo, Z.1
Dai, B.2
Jiang, T.3
Xu, K.4
Xie, Y.5
Kim, O.6
-
31
-
-
77955121375
-
Identification of a cell of origin for human prostate cancer
-
Goldstein AS, Huang J, Guo C, Garraway IP, Witte ON. Identification of a cell of origin for human prostate cancer. Science. 2010; 329: 568-71.
-
(2010)
Science
, vol.329
, pp. 568-571
-
-
Goldstein, A.S.1
Huang, J.2
Guo, C.3
Garraway, I.P.4
Witte, O.N.5
-
32
-
-
79952772097
-
Intragenic rearrangement and altered RNA splicing of the androgen receptor in a cell-based model of prostate cancer progression
-
Li Y, Alsagabi M, Fan D, Bova GS, Tewfik AH, Dehm SM. Intragenic rearrangement and altered RNA splicing of the androgen receptor in a cell-based model of prostate cancer progression. Cancer Res. 2011; 71: 2108-17.
-
(2011)
Cancer Res
, vol.71
, pp. 2108-2117
-
-
Li, Y.1
Alsagabi, M.2
Fan, D.3
Bova, G.S.4
Tewfik, A.H.5
Dehm, S.M.6
-
33
-
-
0042978480
-
Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer
-
Edwards J, Krishna NS, Grigor KM, Bartlett JM. Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer. Br J Cancer. 2003; 89: 552-6.
-
(2003)
Br J Cancer
, vol.89
, pp. 552-556
-
-
Edwards, J.1
Krishna, N.S.2
Grigor, K.M.3
Bartlett, J.M.4
|