A nonsteroidal glucocorticoid receptor agonist inhibits allergen-induced late asthmatic responses

American Journal of Respiratory and Critical Care Medicine

Volumn 191, Issue 2, 2015, Pages 161-167

  Gauvreau, Gail M ^a   Boulet, Louis Philippe ^b   Leigh, Richard ^c   Cockcroft, Donald W ^d   Killian, Kieran J ^a   Davis, Beth E ^d   Deschesnes, Francine ^b   Watson, Richard M ^a   Swystun, Veronica ^c   Ma˚rdh, Carina Kärrman ^e   Wessman, Peter ^e   Jorup, Carin ^e   Aurivillius, Magnus ^e   O'Byrne, Paul M ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b LAVAL UNIVERSITY   (Canada)

^c UNIVERSITY OF CALGARY   (Canada)

^d UNIVERSITY OF SASKATCHEWAN   (Canada)

^e ASTRAZENECA R AND D   (Sweden)

Author keywords

Airway hyperresponsiveness; Allergen inhalation challenge; AZD5423; Late asthmatic response; Sputum eosinophils

Indexed keywords

ALLERGEN; ANTIASTHMATIC AGENT; AZD 5423; BUDESONIDE; METHACHOLINE; NONSTEROIDAL GLUCOCORTICOID RECEPTOR AGONIST; PLACEBO; UNCLASSIFIED DRUG; GLUCOCORTICOID RECEPTOR; NONSTEROID ANTIINFLAMMATORY AGENT;

ADULT; ALLERGIC ASTHMA; ARTICLE; BRONCHITIS; BRONCHUS HYPERREACTIVITY; CLINICAL ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; EOSINOPHILIA; FEMALE; FORCED EXPIRATORY VOLUME; HEADACHE; HUMAN; HUMAN CELL; INFLAMMATORY CELL; MALE; METERED DOSE INHALER; MULTICENTER STUDY; OROPHARYNX PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SPUTUM ANALYSIS; TREATMENT DURATION; TREATMENT RESPONSE; YOUNG ADULT; ADOLESCENT; AGONISTS; ASTHMA; CLINICAL TRIAL; CYTOLOGY; DRUG EFFECTS; INHALATIONAL DRUG ADMINISTRATION; MIDDLE AGED; PHYSIOLOGY; SPUTUM;

ADMINISTRATION, INHALATION; ADOLESCENT; ADULT; ALLERGENS; ANTI-ASTHMATIC AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASTHMA; CROSS-OVER STUDIES; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; MALE; MIDDLE AGED; RECEPTORS, GLUCOCORTICOID; SPUTUM; YOUNG ADULT;

EID: 84921324627     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201404-0623OC     Document Type: Article

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