R-(+) and S-(-) isomers of cotinine augment cholinergic responses in vitro and in vivo

Journal of Pharmacology and Experimental Therapeutics

Volumn 352, Issue 2, 2015, Pages 405-418

  Terry, Alvin V ^a   Callahan, Patrick M ^a   Bertrand, Daniel ^b  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b HiQScreen Sarl   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; BUNGAROTOXIN RECEPTOR; COTININE; DIHYDRO BETA ERYTHROIDINE; DONEPEZIL; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; HISTAMINE H1 RECEPTOR; HISTAMINE H2 RECEPTOR; HISTAMINE H3 RECEPTOR; METHYLLYCACONITINE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC M4 RECEPTOR; MUSCARINIC M5 RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NICOTINIC RECEPTOR ALPHA4BETA2; NORADRENALIN TRANSPORTER; SEROTONIN 1A RECEPTOR; SEROTONIN 1D RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 3 RECEPTOR; SEROTONIN 4 RECEPTOR; SEROTONIN 5A RECEPTOR; SEROTONIN 6 RECEPTOR; CHOLINERGIC RECEPTOR STIMULATING AGENT; INDAN DERIVATIVE; NICOTINIC RECEPTOR; PIPERIDINE DERIVATIVE;

ALZHEIMER DISEASE; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CHOLINERGIC ACTIVITY; COGNITION; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; EXPLORATORY BEHAVIOR; HABITUATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MEMORY CONSOLIDATION; MEMORY DISORDER; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; OOCYTE; PROTEIN EXPRESSION; RAT; TASK PERFORMANCE; XENOPUS; ANIMAL; CHEMISTRY; DRUG EFFECTS; DRUG POTENTIATION; EVOKED RESPONSE; GENETICS; MEMORY; METABOLISM; PATTERN RECOGNITION; STEREOISOMERISM; WISTAR RAT; XENOPUS LAEVIS;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANIMALS; BEHAVIOR, ANIMAL; CHOLINERGIC AGENTS; COTININE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; EVOKED POTENTIALS; HUMANS; INDANS; MALE; MEMORY; OOCYTES; PATTERN RECOGNITION, VISUAL; PIPERIDINES; RATS, WISTAR; RECEPTORS, NICOTINIC; STEREOISOMERISM; XENOPUS LAEVIS;

EID: 84921297464     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.114.219881     Document Type: Article

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