Schistosomiasis in pre-school-age children and their mothers in Chikhwawa district, Malawi with notes on characterization of schistosomes and snails

Parasites and Vectors

Volumn 7, Issue 1, 2014, Pages

  Poole, Helen ^a   Terlouw, Dianne J ^a,b   Naunje, Andrew ^b   Mzembe, Kondwani ^b   Stanton, Michelle ^a   Betson, Martha ^a   Lalloo, David G ^a   Stothard, J Russell ^a  

^a LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^b MALAWI LIVERPOOL WELLCOME TRUST CLINICAL RESEARCH PROGRAMME   (Malawi)

Author keywords

Praziquantel; Preventive chemotherapy; Schistosoma haematobium; Schistosoma mansoni; SEA ELISA; Zoonosis

Indexed keywords

ALBUMIN; PRAZIQUANTEL; ANTHELMINTIC AGENT;

ADULT; ALBUMINURIA; ANEMIA; ANTIBODY DETECTION; ARTICLE; BIOMPHALARIA; BULINUS; CHILD; CONTROLLED STUDY; DISEASE TRANSMISSION; DNA BARCODING; FEMALE; HEMATURIA; HUMAN; INFANT; INTESTINAL SCHISTOSOMIASIS; MAJOR CLINICAL STUDY; MALAWI; MALE; MIXED INFECTION; MORBIDITY; NUCLEOTIDE SEQUENCE; PRESCHOOL CHILD; PREVALENCE; SCHISTOSOMA; SCHISTOSOMA HEMATOBIUM; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; SCHISTOSOMIASIS HAEMATOBIA; SCHISTOSOMIASIS MANSONI; SEROPREVALENCE; URINALYSIS; URINARY TRACT; UROGENITAL SCHISTOSOMIASIS; ADOLESCENT; AGING; ANIMAL; CLASSIFICATION; EPIDEMIOLOGY; GENETICS; MIDDLE AGED; PARASITOLOGY; PHYSIOLOGY; SNAIL;

ADOLESCENT; ADULT; AGING; ANIMALS; ANTHELMINTICS; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; MALAWI; MALE; MIDDLE AGED; PRAZIQUANTEL; PREVALENCE; SCHISTOSOMA; SCHISTOSOMIASIS; SNAILS;

EID: 84921283882     PISSN: None     EISSN: 17563305     Source Type: Journal    
DOI: 10.1186/1756-3305-7-153     Document Type: Article

References (57)

1. Schistosomiasis. Chitsulo L, Loverde R, Engels D, Barakat R, Colley D, Cioli D, Feldmeier H, LoVerde P, Olds GR, Ouma J, Rabello A, Savioli L, Traore M, Vennerwald B, Nat Rev Microbiol 2004 2 12 13 15035004
2. Brown DS, Freshwater Snails of Africa and their Medical Importance Taylor & Francis 2 1994
3. Environmental epidemiology of intestinal schistosomiasis and genetic diversity of Schistosoma mansoni infections in snails at Bugoigo village, Lake Albert. Levitz S, Standley CJ, Adriko M, Kabatereine NB, Stothard JR, Acta Trop 2013 128 284 291 10.1016/j.actatropica.2012.10.003 23085327
4. Epidemiology and control of intestinal schistosomiasis on the Sesse Islands, Uganda: integrating malacology and parasitology to tailor local treatment recommendations. Standley CJ, Adriko M, Arinaitwe M, Atuhaire A, Kazibwe F, Fenwick A, Kabatereine NB, Stothard JR, Parasit Vectors 2010 3 64 10.1186/1756-3305-3-64 20663223
5. Parasitological and malacological surveys reveal urogenital schistosomiasis on Mafia Island, Tanzania to be an imported infection. Stothard JR, Ameri H, Khamis IS, Blair L, Nyandindi US, Kane RA, Johnston DA, Webster BL, Rollinson D, Acta Trop 2013 128 326 333 10.1016/j.actatropica.2012.09.006 23010161
6. Confirmed local endemicity and putative high transmission of Schistosoma mansoni in the Sesse Islands, Lake Victoria, Uganda. Standley CJ, Adriko M, Besigye F, Kabatereine NB, Stothard RJ, Parasit Vectors 2011 4 29 10.1186/1756-3305-4-29 21362166
7. Urinary schistosomiasis-associated morbidity in schoolchildren detected with urine albumin-to-creatinine ratio (UACR) reagent strips. Stothard JR, Sousa-Figueiredo JC, Khamis IS, Garba A, Rollinson D, J Pediatr Urol 2009 5 287 291 10.1016/j.jpurol.2008.09.010 19168393
8. Hybridisation between the two major African schistosome species of humans. Huyse T, Van den Broeck F, Hellemans B, Volckaert FAM, Polman K, Int J Parasitol 2013 43 687 689 10.1016/j.ijpara.2013.04.001 23643461
9. Introgressive hybridization of Schistosoma haematobium group species in Senegal: Species barrier break down between ruminant and human schistosomes. Webster BL, Diaw OT, Seye MM, Webster JP, Rollinson D, PLoS Negl Trop Dis 2013 7 2110 10.1371/journal.pntd.0002110 23593513
10. Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk. Steinmann P, Keiser J, Bos R, Tanner M, Utzinger J, Lancet Infect Dis 2006 6 411 425 10.1016/S1473-3099(06) 70521-7 16790382
11. WHO, Progress Report 2001-2011 and Strategic Plan 2012-2020 WHO 2013
12. Preventive chemotherapy and the fight against neglected tropical diseases. Montresor A, Gabrielli AF, Chitsulo L, Ichimori K, Mariotti S, Engels D, Savioli L, Expert Rev Anti-Infe 2012 10 237 242 10.1586/eri.11.165
13. Schistosomiasis in African infants and preschool children: let them now be treated! Stothard JR, Sousa-Figueiredo JC, Betson M, Bustinduy A, Reinhard-Rupp J, Trends Parasitol 2013 29 197 205 10.1016/j.pt.2013.02.001 23465781
14. Closing the praziquantel treatment gap: new steps in epidemiological monitoring and control of schistosomiasis in African infants and preschool-aged children. Stothard JR, Sousa-Figueiredo JC, Betson M, Green HK, Seto EYW, Garba A, Sacko M, Mutapi F, Nery SV, Amin MA, Mutumba-Nakalembe M, Navaratnam A, Fenwick A, Kabatereine NB, Gabrielli AF, Montresor A, Parasitology 2011 138 1593 1606 10.1017/S0031182011001235 21861945
15. WHO, Report of a Meeting to Review the Results of Studies on the Treatment of Schistosomiasis in Preschool-Age Children Geneva, Switzerland: WHO 2011
16. Schistosomiasis in infants and pre-school-aged children in sub-Saharan Africa: implication for control. Ekpo UF, Oluwole AS, Abe EM, Etta HE, Olamiju F, Mafiana CF, Parasitology 2012 139 835 841 10.1017/S0031182012000029 22313588
17. High level of Schistosoma mansoni infection in pre-school children in Sierra Leone highlights the need in targeting this age group for praziquantel treatment. Hodges MH, Paye J, Koroma MM, Nyorkor ED, Fofonah I, Zhang Y, Acta Trop 2012 124 120 125 10.1016/j.actatropica.2012.07.005 22820025
18. The acceptability and safety of praziquantel alone and in combination with mebendazole in the treatment of Schistosoma mansoni and soil-transmitted helminthiasis in children aged 1-4 years in Uganda. Namwanje H, Kabatereine NB, Olsen A, Parasitology 2011 138 1586 1592 10.1017/S0031182011000138 21349218
19. Efficacy of praziquantel syrup versus crushed praziquantel tablets in the treatment of intestinal schistosomiasis in Ugandan preschool children, with observation on compliance and safety. Navaratnam AMD, Sousa-Figueiredo JC, Stothard JR, Kabatereine NB, Fenwick A, Mutumba-Nakalembe MJ, Trans R Soc Trop Med Hyg 2012 106 400 407 10.1016/j.trstmh.2012.03.013 22657533
20. Performance and safety of praziquantel for treatment of intestinal schistosomiasis in infants and preschool children. Sousa-Figueiredo JC, Betson M, Atuhaire A, Arinaitwe M, Navaratnam AMD, Kabatereine NB, Bickle Q, Stothard JR, PLoS Negl Trop Dis 2012 6 1864 10.1371/journal.pntd.0001864 23094120
21. Notes on the use of urine-CCA dipsticks for detection of intestinal schistosomiasis in preschool children. Navaratnam AMD, Mutumba-Nakalembe MJ, Stothard JR, Kabatereine NB, Fenwick A, Sousa-Figueiredo JC, Trans R Soc Trop Med Hyg 2012 106 619 622 10.1016/j.trstmh.2012.06.010 22858241
22. Treatment of intestinal schistosomiasis in Ugandan preschool children: best diagnosis, treatment efficacy and side-effects, and an extended praziquantel dosing pole. Sousa-Figueiredo JC, Pleasant J, Day M, Betson M, Rollinson D, Montresor A, Kazibwe F, Kabatereine NB, Stothard JR, Int Health 2010 2 103 113 10.1016/j.inhe.2010.02.003 20640034
23. Diagnosis and treatment of schistosomiasis in children in the era of intensified control. Knopp S, Becker SL, Ingram KJ, Keiser J, Utzinger J, Expert Rev Anti-Infe 2013 11 1237 1258 10.1586/14787210.2013.844066
24. Advocacy, policies and practicalities of preventive chemotherapy campaigns for African children with schistosomiasis. Stothard JR, Sousa-Figueiredo JC, Navaratnam AMD, Expert Rev Anti-Infe 2013 11 733 752 10.1586/14787210.2013.811931
25. Schistosoma mansoni infections in young children: When are schistosome antigens in urine, eggs in stool and antibodies to eggs first detectable? Stothard JR, Sousa-Figuereido JC, Betson M, Adriko M, Arinaitwe M, Rowell C, Besiyge F, Kabatereine NB, PLoS Negl Trop Dis 2011 5 938 10.1371/journal.pntd. 0000938 21245910
26. An evaluation of urine-CCA strip test and fingerprick blood SEA-ELISA for detection of urinary schistosomiasis in schoolchildren in Zanzibar. Stothard JR, Sousa-Figueiredo JC, Standley C, Van Dam GJ, Knopp S, Utzinger J, Ameri H, Khamis AN, Khamis IS, Deelder AM, Mohammed KA, Rollinson D, Acta Trop 2009 111 64 70 10.1016/j.actatropica.2009.02.009 19426665
27. The urine circulating cathodic antigen (CCA) dipstick: A valid substitute for microscopy for mapping and point-of-care diagnosis of intestinal schistosomiasis. Sousa-Figueiredo JC, Betson M, Kabatereine NB, Stothard JR, PLoS Negl Trop Dis 2013 7 2008 10.1371/journal.pntd.0002008 23359826
28. Intestinal schistosomiasis in mothers and young children in uganda investigation of field-applicable markers of bowel morbidity. Betson M, Figueiredo JCS, Rowell C, Kabatereine NB, Stothard JR, Am J Trop Med Hyg 2010 83 1048 1055 10.4269/ajtmh.2010.10-0307 21036836
29. Use of fecal occult blood tests as epidemiologic indicators of morbidity associated with intestinal schistosomiasis during preventive chemotherapy in young children. Betson M, Sousa-Figueiredo JC, Kabatereine NB, Stothard JR, Am J Trop Med Hyg 2012 87 694 700 10.4269/ajtmh.2012.12-0059 22927499
30. A new rapid diagnostic test for detection of anti-Schistosoma mansoni and anti-Schistosoma haematobium antibodies. Coulibaly JT, N'Goran EK, Utzinger J, Doenhoff MJ, Dawson EM, Parasit Vectors 2013 6 29 10.1186/1756-3305-6-29 23360734
31. Schistosomiasis in infants and preschool-aged children: Infection in a single Schistosoma haematobium and a mixed S. haematobium-S. mansoni foci of Niger. Garba A, Barkire N, Djibo A, Lamine MS, Sofo B, Gouvras AN, Bosque-Oliva E, Webster JP, Stothard JR, Utzinger J, Fenwick A, Acta Trop 2010 115 212 219 10.1016/j.actatropica.2010.03.005 20303925
32. Urinary schistosomiasis on Zanzibar: application of two novel assays for the detection of excreted albumin and haemoglobin in urine. Rollinson D, Klinger EV, Mgeni AE, Khamis IS, Stothard JR, J Helminthol 2005 79 199 206 10.1079/JOH2005305 16153313
33. Measuring morbidity associated with urinary schistosomiasis: Assessing levels of excreted urine albumin and urinary tract pathologies. Sousa-Figueiredo JC, Basanez M-G, Khamis IS, Garba A, Rollinson D, Stothard JR, PLoS Negl Trop Dis 2009 3 526 10.1371/journal.pntd.0000526 19806223
34. Evaluation and application of potential schistosome-associated morbidity markers within large-scale mass chemotherapy programmes. Webster JP, Koukounari A, Lamberton PHL, Stothard JR, Fenwick A, Parasitology 2009 136 1789 1799 10.1017/S0031182009006350 19523252
35. Short Report: Rolling malaria indicator surveys (rMIS): A potential district-level malaria monitoring and evaluation (M & E) tool for program managers. Roca-Feltrer A, Lalloo DG, Phiri K, Terlouw DJ, Am J Trop Med Hyg 2012 86 96 98 10.4269/ajtmh.2012.11-0397 22232457
36. Experience with a monthly 'rolling' malaria indicator survey (RMIS) in Chikwawa district, Malawi: a potential district-level malaria monitoring and evaluation (M & E) tool. Roca-Feltrer A, Saito K, Phiri K, Lalloo D, Terlouw D, Trop Med Int Health 2011 16 114 115
37. A five-country evaluation of a point-of-care Circulating Cathodic Antigen urine assay for the prevalence of Schistosoma mansoni. Colley DG, Binder S, Campbell C, King CH, Tchuente L-AT, N'Goran EK, Erko B, Karanja DMS, Kabatereine NB, van Lieshout L, Rathbun S, Am J Trop Med Hyg 2013 88 426 432 10.4269/ajtmh.12-0639 23339198
38. Use of circulating cathodic antigen (CCA) dipsticks for detection of intestinal and urinary schistosomiasis. Stothard JR, Kabatereine NB, Tukahebwa EM, Kazibwe F, Rollinson D, Mathieson W, Webster JP, Fenwick A, Acta Trop 2006 97 219 228 10.1016/j.actatropica.2005.11.004 16386231
39. Intestinal schistosomiasis in chimpanzees on Ngamba Island, Uganda: observations on liver fibrosis, schistosome genetic diversity and praziquantel treatment. Standley CJ, Mugisha L, Adriko M, Arinaitwe M, Rukundo J, Ajarova L, Mopya S, Betson M, Kabatereine NB, Stothard JR, Parasitology 2013 140 285 295 10.1017/S0031182012001576 23095137
40. Genetic diversity within Schistosoma haematobium: DNA barcoding reveals two distinct groups. Webster BL, Emery AM, Webster JP, Gouvras A, Garba A, Diaw O, Seye MM, Tchuente LAT, Simoonga C, Mwanga J, Lange C, Kariuki C, Mohammed KA, Stothard JR, Rollinson D, PLoS Negl Trop Dis 2012 6 1882 10.1371/journal.pntd. 0001882 23145200
41. DNA 'barcoding' of Schistosoma mansoni across sub-Saharan Africa supports substantial within locality diversity and geographical separation of genotypes. Webster BL, Webster JP, Gouvras AN, Garba A, Lamine MS, Diaw OT, Seye MM, Tchuem Tchuenté L-A, Simoonga C, Mubila L, Mwanga J, Lwambo NJS, Kabatereine NB, Lange CN, Kariuki C, Mkoji G, Rollinson D, Stothard JR, Acta Trop 2013 128 250 260 10.1016/j.actatropica.2012.08.009 22935316
42. Analysis of Schistosomiasis haematobium infection prevalence and intensity in Chikhwawa, Malawi: An application of a two part model. Chipeta MG, Ngwira B, Kazembe LN, PLoS Negl Trop Dis 2013 7 2131 10.1371/journal.pntd. 0002131 23556017
43. Schistosomiasis prevalence in Zomba, Southern Malawi. Pullanikkatil D, Mubako S, Phalira W, Chiotha S, Luhanga M, Afr Geogr Rev 2014 33 36 51
44. An outbreak of schistosomiasis in travellers returning from endemic areas: The importance of rigorous tracing in peer groups exposed to risk of infection. Blach O, Rai B, Oates K, Franklin G, Bramwell S, J Public Health 2012 34 32 36 10.1093/pubmed/fdr099
45. Short Report: acute schistosomiasis in travelers: 14 Years' experience at the Hospital for tropical diseases, London. Logan S, Armstrong M, Moore E, Nebbia G, Jarvis J, Suvari M, Bligh J, Chiodini PL, Brown M, Doherty T, Am J Trop Med Hyg 2013 88 1032 1034 10.4269/ajtmh.12-0646 23530076
46. Schistosomiasis in Lake Malawi Villages. Madsen H, Bloch P, Makaula P, Phiri H, Furu P, Stauffer JR Jr, Ecohealth 2011 8 163 176 10.1007/s10393-011- 0687-9 21598059
47. Patterns of intestinal schistosomiasis among mothers and young children from Lake Albert, Uganda: water contact and social networks inferred from wearable global positioning system dataloggers. Seto EYW, Sousa-Figueiredo JC, Betson M, Byalero C, Kabatereine NB, Stothard JR, Geospat Health 2012 7 1 13 23242675
48. A pocket chart to estimate true Schistosoma mansoni prevalences. Devlas SJ, Gryseels B, Vanoortmarssen GJ, Polderman AM, Habbema JDF, Parasitol Today 1993 9 305 307 15463790
49. Modeling the effect of chronic schistosomiasis on childhood development and the potential for catch-up growth with different drug treatment strategies promoted for control of endemic schistosomiasis. Gurarie D, Wang X, Bustinduy AL, King CH, Am J Trop Med Hyg 2011 84 773 781 10.4269/ajtmh.2011.10-0642 21540388
50. Evaluation of the health-related Quality of Life of children in Schistosoma haematobium-endemic communities in Kenya: a cross-sectional study. Terer CC, Bustinduy AL, Magtanong RV, Muhoho N, Mungai PL, Muchiri EM, Kitron U, King CH, Mutuku FM, PLoS Negl Trop Dis 2013 7 2106 10.1371/journal.pntd.0002106 23505590
51. HIV and schistosomasis coinfection in African children. Bustinduy AL, King CH, Scott J, Appleton S, Sousa-Figueiredo JC, Betson M, Stothard JR, Lancet Infect Dis in press
52. Improving diagnosis of urogenital schistosome infection. Mutapi F, Exp Rev Anti-Infe 2011 9 863 865 10.1586/eri.11.101
53. Exposure, infection, systemic cytokine levels and antibody responses in young children concurrently exposed to schistosomiasis and malaria. Imai N, Rujeni N, Nausch N, Bourke CD, Appleby LJ, Cowan G, Gwisai R, Midzi N, Cavanagh D, Mduluza T, Taylor D, Mutapi F, Parasitology 2011 138 1519 1533 10.1017/S0031182011001181 21813042
54. A national survey of the prevalence of schistosomiasis and soil transmitted helminths in Malawi. Bowie C, Purcell B, Shaba B, Makaula P, Perez M, BMC Infect Dis 2004 4 49 10.1186/1471-2334-4-49 15546483
55. Sentinel surveillance of lymphatic filariasis, schistosomiasis, soil transmitted helminths and malaria in rural southern Malawi. Msyamboza K, Ngwira B, Banda R, Mkwanda S, Brabin B, Malawi Med J 2010 22 12 14 21618842
56. The burrowing behaviour of Bulinus nyassanus, intermediate host of Schistosoma haematobium, in Lake Malawi. Madsen H, Stauffer JR Jr, Afr J Aquat Sci 2012 37 113 116 10.2989/16085914.2012.666383
57. Schistosoma haematobium in Lake Malawi: susceptibility and molecular diversity of the snail hosts Bulinus globous and B. nyassanus. Stauffer JR Jr, Madsen H, Webster B, Black K, Rollinson D, Konings A, J Helminthol 2008 82 377 382 10.1017/S0022149X08056290 18752711