The acceptability and safety of praziquantel alone and in combination with mebendazole in the treatment of Schistosoma mansoni and soil-transmitted helminthiasis in children aged 1-4 years in Uganda

Parasitology

Volumn 138, Issue 12, 2011, Pages 1586-1592

  Namwanje, Harriet ^a   Kabatereine, Narcis B ^a   Olsen, Annette ^b  

^a MINISTRY OF HEALTH   (Uganda)

^b DANISH BILHARZIASIS LABORATORY   (Denmark)

Author keywords

mebendazole; praziquantel; pre school children; Schistosoma mansoni; soil transmitted helminthiasis; Uganda

Indexed keywords

MEBENDAZOLE; PRAZIQUANTEL;

ARTICLE; CHILD; COMMUNITY; CONTROLLED STUDY; DISEASE TRANSMISSION; DRUG SAFETY; FISHING; HELMINTHIASIS; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; UGANDA; UNSPECIFIED SIDE EFFECT;

ANIMALS; ANTHELMINTICS; ASCARIASIS; ASCARIS LUMBRICOIDES; CHILD, PRESCHOOL; DRUG THERAPY, COMBINATION; FECES; FEMALE; HELMINTHIASIS; HOOKWORM INFECTIONS; HUMANS; INFANT; MALE; MEBENDAZOLE; PARASITE EGG COUNT; PRAZIQUANTEL; PREVALENCE; QUESTIONNAIRES; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; SINGLE-BLIND METHOD; SOIL; TREATMENT OUTCOME; TRICHURIASIS; UGANDA;

SCHISTOSOMA MANSONI;

EID: 84855708404     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182011000138     Document Type: Article

References (27)

1. Berhe, N., Medhin, G., Erko, B., Smith, T., Gedamu, S., Bereded, D., Moore, R., Habte, E., Redda, A., Gebre-Michael, T. and Gundersen, S. G. (2004). Variations in helminth faecal egg counts in Kato-Katz thick smears and their implications in assessing infection status with Schistosoma mansoni. Acta Tropica 92, 205-212. doi: 10.1016/j. actatropica.2004.06.011
2. Bosompem, K. M., Bentum, I. A., Otchere, J., Anyan, W. K., Brown, C. A., Osada, Y., Takeo, S., Kojima, S. and Otha, N. (2004). Infant schistosomiasis in Ghana: a survey in an irrigation community. Tropical Medicine and International Health 9, 917-922. doi: 10.1111/j.1365-3156200401282.x
3. De Vlas, S. J., Gryseels, B., van Oortmarssen, G. J., Polderman, A. M.and Habbema, J. D. (1993). Validation of a chart to estimate true Schistosoma mansoni prevalences. Parasitology Today 9, 305-307.
4. Doenhoff, M. J., Hagan, P., Cioli, D., Southgate, V., Pica-Mattoccia, L., Botros, S., Coles, G., Tchuem Tchuenté, L. A., Mbaye, A. and Engels, D. (2009). Praziquantel: its use in control of schistosomiasis in sub-Saharan Africa and current research needs. Parasitology 136, 1825-1835. doi:10.1017/S0031182009990493
5. Ekpo, U. F., Laja-Deile, A., Oluwole, A. S., Sam-Wobo, S. O. and Mafiana, C. F. (2010). Urinary schistosomiasis among preschool children in a rural community near Abeokuta, Nigeria. Parasites and Vectors 3, 58. doi: 10.1186/1756-3305-3-58
6. Engels, D., Ndoricimpa, J. and Gryseels, B. (1993). Schistosomiasis mansoni in Burundi: progress in its control since 1985. Bulletin of the World Health Organization 71, 207-214.
7. Fenwick, A., Webster, J. P., Bosgue-Oliva, E., Blair, L., Fleming, F. M., Zhang, Y., Garba, A., Stothard, J. R.,Gabrielli, A. F., Clements, A. C., Kabatereine, N. B., Toure, S., Dembele, R., Nyandindi, U., Mwansa, J. and Koukounari, A. (2009). The Schistosomiasis Control Initiative (SCI): rationale, development and implementation from 2002-2008. Parasitology 136, 1719-1760. doi: 10.1017/S0031182009990400
8. Fleming, F. M., Fenwick, A., Tukahebwa, E. M., Lubanga, R. G., Namwangye, H., Zaramba, S. and Kabatereine, N. B. (2009). Process evaluation of schistosomiasis control in Uganda, 2003 to 2006: perceptions, attitudes and constraints of a national programme. Parasitology 136, 1759-1769. doi: 10.1017/S0031182009990709
9. Garba, A., Barkiré, N., Djibo, A., Lamine, M. S., Sofo, B., Gouvras, A. N., Bosqué-Oliva, E., Webster, J. P., Stothard, J. R., Utzinger, J. and Fenwick, A. (2010). Schistosomiasis in infants and preschool-aged children: Infection in a single Schistosoma haematobium and a mixed S. haematobium-S. mansoni foci of Niger. Acta Tropica 115, 212-219. doi: 10.1016/j.actatropica.2010.03.005
10. Gardner, M. J. and Altman, D. G. (1989). Statistics with Confidence. Confidence Intervals and Statistical Guidelines. London. British Medical Journal. The Universities Press.
11. Hald, A. (1973). Statistiske Metoder. Tabel-og Formelsamling [In Danish]. Copenhagen. Akademisk Forlag.
12. Homeida, M., Leahy,W., Copeland, S., Ali, M. M. and Harron, D.W. (1994). Pharmacokinetic interaction between praziquantel and albendazole in Sudanese men. Annals of Tropical Medicine and Parasitology 88, 551-559.
13. Johansen, M. V., Sacko, M., Vennervald, B. J. and Kabatereine, N. B. (2007). Leave children untreated and sustain inequity! Trends in Parasitology 23, 568-569.
14. Kabatereine, N. B., Ariho, C. and Christensen, N. O. (1992). Schistosoma mansoni in Pachwach, Nebbi-District, Uganda, 40 years after Nelson. Tropical Medicine and Parasitology 43, 162-166.
15. Kabatereine, N. B., Kemijumbi, J., Ouma, J. H., Sturrock, R. F., Butterworth, A. E., Madsen, H., Ornbjerg, N., Dunne, D.W. and Vennnervald, B. J. (2003). Efficacy and side effects of praziquantel treatment in a highly endemic Schistosoma mansoni focus at Lake Albert, Uganda. Transactions of the Royal Society of Tropical Medicine and Hygiene 97, 599-603.
16. Kabatereine, N. B., Tukahebwa, E. M., Kazibwe, F., Namwangye, H., Zaramba, S., Brooker, S., Stothard, J. R., Kamenka, C., Whawell, S., Webster, J. P. and Fenwick, A. (2006). Progress towards countrywide control of schistosomiasis and soiltransmitted helminthiasis in Uganda. Transactions of the Royal Society of Tropical Medicine and Hygiene 100, 208-215. doi:10.1016/j.trstmh. 2005.03.015
17. Keiser, J., N'Guessan, N. A., Adoubryn, K. D., Silué, K. D., Vounatsou, P., Hatz, C., Utzinger, J. and N'Goran, E. K. (2010). Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, and praziquantel against Schistosoma haematobium: randomized, exploratory open-label trial. Clinical Infectious Diseases 50, 1205-1213. doi: 10.1086/ 651682
18. Odogwu, S. E., Ramamurthy, N. K., Kabatereine, N. B., Kazibwe, F., Tukahebwa, E., Webster, J. P., Fenwick, A. and Stothard, J. R. (2006). Schistosoma mansoni in infants (aged <3 years) along the Ugandan shoreline of Lake Victoria<3 years along the Ugandan shoreline of Lake Victoria. Annals of Tropical Medicine and Parasitology 100, 315-326. 10.1179/ 136485906X105552
19. Sousa-Figueiredo, J. C., Pleasant, J., Day, M., Betson, M., Rollinson, D., Montresor, A., Kazibwe, F., Kabaterine, N. B. and Stothard, J. R. (2010). Treatment of intestinal schistosomiasis in Ugandan preschool children: best diagnosis, treatment efficacy and side-effects, and an extended praziquantel dosing pole. International Health 2, 103-113. doi: 10.1016/j.inhe.2010.02.003
20. Stothard, J. R. and Gabrielli, A. F. (2007). Response to Johansen et al.: Leave children untreated and sustain inequity! Trends in Parasitology 23, 569-570.
21. Stothard, J. R., Pleasant, J., Oguttu, D., Adriko, M., Galimaka, R., Ruggiana, A., Kazibwe, F. and Kabatereine, N. B. (2008). Strongyloides stercoralis: a field-based survey of mothers and their preschool children using ELISA, Baermann and Koga plate methods reveals low endemicity inwestern Uganda. Journal of Helminthology 82, 263-269. doi: 10.1017/ S0022149X08971996
22. Stothard, J. R., Sousa-Figuereido, J. C., Betson, M., Adriko, M., Arinaitwe, M., Rowell, C., Besiyge, F. and Kabatereine, N. B. (2011). Schistosoma mansoni infections in young children: When are schistosome antigens in urine, eggs in stool and antibodies to eggs first detectable? PLoS Neglected Tropical Diseases 5(1): e938. doi:10.1371/ journal.pntd.0000938
23. Guidelines for good clinical practice GCP for trials on pharmaceutical products. WHO Technical Report. 1995. 850. World Health Organizati Series No World Health Organization Geneva
24. World Health Organization (2002). Prevention and Control of Schistosomiasis and Soil-transmitted Helminthiasis. A Report of a WHOExpert Committee. WHO Technical Report Series No. 912. World Health Organization, Geneva
25. World Health Organization (2004). Bench Aid for the Diagnosis of Intestinal Parasites. World Health Organization, Geneva.
26. World Health Organization (2006 Preventive Chemotherapy in Human Helminthiasis. Coordinated use of Anthelminthic Drugs in Human Interventions:AManual for Health Professionals and Programme Managers. World Health Organization, Geneva
27. Woolhouse, M. E., Mutapi, F., Ndhlovu, P. D., Chandiwana, S. K. and Hagan, P. (2000). Exposure, infection and immune responses to Schistosoma haematobium in young children. Parasitology 120, 37-44. doi: 10.1017/S0031182099005156