Treatment of intestinal schistosomiasis in Ugandan preschool children: best diagnosis, treatment efficacy and side-effects, and an extended praziquantel dosing pole

International Health

Volumn 2, Issue 2, 2010, Pages 103-113

  Sousa Figueiredo, José Carlos ^a,b   Pleasant, Joyce ^b   Day, Matthew ^c   Betson, Martha ^a   Rollinson, David ^a   Montresor, Antonio ^d   Kazibwe, Francis ^e   Kabatereine, Narcis B ^e   Stothard, J Russell ^a  

^a Department of Zoology   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

^d WORLD HEALTH ORGANIZATION   (Switzerland)

^e MINISTRY OF HEALTH   (Uganda)

Author keywords

deworming; guidelines; national control programme; preschoolaged children (PSAC); Schistosomiasis

Indexed keywords

ALBENDAZOLE; PRAZIQUANTEL;

ABDOMINAL PAIN; AIRWAY OBSTRUCTION; ARTICLE; BODY HEIGHT; BODY WEIGHT; CHILD; CHILDHOOD DISEASE; CONTROLLED STUDY; COUGHING; DIARRHEA; DIZZINESS; DOSE RESPONSE; DRUG EFFICACY; DRUG SAFETY; FATIGUE; FECES ANALYSIS; FEMALE; HEADACHE; HEALTH CARE DISPARITY; HUMAN; INFANT; INFECTION RISK; INTESTINE INFECTION; LOW BACK PAIN; MAJOR CLINICAL STUDY; MALE; MUSCLE CRAMP; NAUSEA; OPTIMAL DRUG DOSE; PRESCHOOL CHILD; PRIORITY JOURNAL; RASH; RISK FACTOR; SCHISTOSOMIASIS; SOMNOLENCE; UGANDA; URTICARIA; VERTIGO; VOMITING;

EID: 77953123966     PISSN: 18763413     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.inhe.2010.02.003     Document Type: Article

References (49)

1. Gryseels B., Polman K., Clerinx J., and Kestens L. Human schistosomiasis. Lancet 368 (2006) 1106-1118
2. Yamey G. The world's most neglected diseases. BMJ 325 (2002) 176-177
3. WHO. Deworming for health and development. Report of the third global meeting of the partners for parasite control (WHO/CDS/CPE/PVC/2005.14). Geneva: World Health Organization; 2005.
4. WHO. The evidence is in: deworming helps meet the Millennium Development Goals (WHO/CDS/CPE/PVC/2005.12). Geneva: World Health Organization; 2005.
5. WHO. World Health Assembly endorses WHO's strategic priorities. Geneva: World Health Organization; 2001.
6. Hotez P.J., Molyneux D.H., Fenwick A., Ottesen E., Ehrlich Sachs S., and Sachs J.D. Incorporating a rapid-impact package for neglected tropical diseases with programs for HIV/AIDS, tuberculosis, and malaria. PLoS Med 3 (2006) e102
7. Fenwick A. New initiatives against Africa's worms. Trans R Soc Trop Med Hyg 100 (2006) 200-207
8. Fenwick A., Webster J.P., Bosque-Oliva E., et al. The Schistosomiasis Control Initiative (SCI): rationale, development and implementation from 2002-2008. Parasitology (2009) 1-12
9. Kabatereine N.B., Fleming F.M., Nyandindi U., Mwanza J.C., and Blair L. The control of schistosomiasis and soil-transmitted helminths in East Africa. Trends Parasitol 22 (2006) 332-339
10. Bosompem K.M., Bentum I.A., Otchere J., et al. Infant schistosomiasis in Ghana: a survey in an irrigation community. Trop Med Int Health 9 (2004) 917-922
11. Guyatt H.L., Brooker S., and Donnelly C.A. Can prevalence of infection in school-aged children be used as an index for assessing community prevalence?. Parasitology 118 (1999) 257-268
12. Odogwu S.E., Ramamurthy N.K., Kabatereine N.B., et al. Schistosoma mansoni in infants (aged <3 years) along the Ugandan shoreline of Lake Victoria. Ann Trop Med Parasitol 100 (2006) 315-326
13. Sousa-Figueiredo J.C., Basáñez M.G., Mgeni A.F., Khamis I.S., Rollinson D., and Stothard J.R. A parasitological survey, in rural Zanzibar, of pre-school children and their mothers for urinary schistosomiasis, soil-transmitted helminthiases and malaria, with observations on the prevalence of anaemia. Ann Trop Med Parasitol 102 (2008) 679-692
14. Stothard J.R., and Gabrielli A.F. Schistosomiasis in African infants and preschool children: to treat or not to treat?. Trends Parasitol 23 (2007) 83-86
15. Woolhouse M.E.J., Mutapi F., Ndhlovu P.D., Chandiwana S.K., and Hagan P. Exposure, infection and immune responses to Schistosoma haematobium in young children. Parasitology 120 (2000) 37-44
16. Montresor A., Stoltzfus R.J., Albonico M., et al. Is the exclusion of children under 24 months from anthelmintic treatment justifiable?. Trans R Soc Trop Med Hyg 96 (2002) 197-199
17. Stothard J.R., Pleasant J., Oguttu D., et al. Strongyloides stercoralis: a field-based survey of mothers and their preschool children using ELISA, Baermann and Koga plate methods reveals low endemicity in western Uganda. J Helminthol 82 (2008) 263-269
18. WHO. Preventive Chemotherapy in Human Helminthiasis. Coordinated use of Anthelminthic Drugs in Human Interventions: a Manual for Health Professionals and Programme Managers. Geneva: World Health Organization; 2006.
19. Montresor A., Odermatt P., and Muth S. The WHO dose pole for the administration of praziquantel is also accurate in non-African populations. Trans R Soc Trop Med Hyg 99 (2005) 78-81
20. Saathoff E., Olsen A., Magnussen P., Kvalsvig J.D., Becker W., and Appleton C.C. Patterns of Schistosoma haematobium infection, impact of praziquantel treatment and re-infection after treatment in a cohort of schoolchildren from rural KwaZulu-Natal/South Africa. BMC Infect Dis 4 (2004) 40
21. Johansen M.V., Sacko M., Vennervald B.J., and Kabatereine N.B. Leave children untreated and sustain inequity!. Trends Parasitol 23 (2007) 568-569
22. Stothard J.R., and Gabrielli A.F. Response to Johansen et al.: Leave children untreated and sustain inequity!. Trends Parasitol 23 (2007) 569-570
23. Brooker S., Kabatereine N.D., Clements A.C., and Stothard J.R. Schistosomiasis control. Lancet 363 (2004) 658-659
24. Katz N., Chavez A., and Pellegrino J. A simple device for quantitative stool thicksmear technique in schistosomiasis mansoni. Rev Inst Med Trop Sao Paulo 14 (1972) 397-400
25. Sorgho H., Bahgat M., Poda J.N., Song W., Kirsten C., Doenhoff M.J., et al. Serodiagnosis of Schistosoma mansoni infections in an endemic area of Burkina Faso: performance of several immunological tests with different parasite antigens. Acta Trop 93 (2005) 169-180
26. Stothard J.R., Kabatereine N.B., Tukahebwa E.M., Kazibwe F., Rollinson D., Mathieson W., et al. Use of circulating cathodic antigen (CCA) dipsticks for detection of intestinal and urinary schistosomiasis. Acta Trop 97 (2006) 219-228
27. Bennett A., and Guyatt H.L. Reducing intestinal nematode infection: efficacy of albendazole and mebendazole. Parasitol Today 16 (2000) 71-74
28. Hall A., Nokes C., Wen S.T., Adjei S., Kihamia C., Mwanri L., et al. Alternatives to bodyweight for estimating the dose of praziquantel needed to treat schistosomiasis. Trans R Soc Trop Med Hyg 93 (1999) 653-658
29. Montresor A., Engels D., Chitsulo L., Bundy D.A., Brooker S., and Savioli L. Development and validation of a 'tablet pole' for the administration of praziquantel in sub-Saharan Africa. Trans R Soc Trop Med Hyg 95 (2001) 542-544
30. Ihaka R., and Gentleman R.R. A language for data analysis and graphics. J Comp Graph Stat 5 (1996) 299-314
31. Armitage P., and Berry G. Statistical Methods in Medical Research. 3rd ed. (1994), Blackwell Scientific Publications, Oxford
32. Fisher R.A. On the interpretation of Chi-square from contingency tables and the calculation of P. J R Stat Soc 85 (1922) 87-94
33. Kirkwood B.R., and Sterne J.A. Essential Medical Statistics. 2nd ed. (2003), Blackwell Science, Oxford
34. Williams C.B. The use of logarithms in the interpretation of certain entomological problems. Ann Appl Bio 24 (1937) 404-414
35. Breslow N.E., and Clayton D.G. Approximate Inference in Generalized Linear Mixed Models. J Am Stat Assoc 88 (1993) 9-25
36. Odongo-Aginya E.I., Kironde F.K., Kabatereine N.B., Kategere P., and Kazibwe F. Effect of seasonal rainfall and other environmental changes, on snail density and infection rates with Schistosoma mansoni fifteen years after the last snails' study in Kigungu, Entebbe, Uganda. East Afr Med J 85 (2008) 556-563
37. Appleton C.C., Ellery W.N., Byskov J., and Mogkweetsinyana S.S. Epidemic transmission of intestinal schistosomiasis in the seasonal part of the Okavango Delta, Botswana. Ann Trop Med Parasitol 102 (2008) 611-623
38. Hotez P.J., Fenwick A., Savioli L., and Molyneux D.H. Rescuing the bottom billion through control of neglected tropical diseases. Lancet 373 (2009) 1570-1575
39. Helmby H. Schistosomiasis and malaria: another piece of the crossreactivity puzzle. Trends Parasitol 23 (2007) 88-90
40. Stoever K., Molyneux D., Hotez P., and Fenwick A. HIV/AIDS, schistosomiasis, and girls. Lancet 373 (2009) 2025-2026
41. Stothard J.R., Webster B.L., Weber T., Nyakaana S., Webster J.P., Kazibwe F., et al. Molecular epidemiology of Schistosoma mansoni in Uganda: DNA barcoding reveals substantial genetic diversity within Lake Albert and Lake Victoria populations. Parasitology 136 (2009) 1813-1824
42. Davis A. Antischistosomal drugs and clinical practice. In: Jordan P., Webbe G., and Sturrock R.F. (Eds). Human Schistosomiasis (1993), CAB International, Wallingford 367-404
43. Kumar V., and Gryseels B. Use of praziquantel against schistosomiasis - a review of current status. Int J Antimicrob Agents 4 (1994) 313-320
44. Utzinger J., N'Goran E.K., N'Dri A., Lengeler C., and Tanner M. Efficacy of praziquantel against Schistosoma mansoni with particular consideration for intensity of infection. Trop Med Int Health 5 (2000) 771-778
45. Raso G., N'Goran E.K., Toty A., Luginbühl A., Adjoua C.A., Tian-Bi N.T., et al. Efficacy and side effects of praziquantel against Schistosoma mansoni in a community of western Cote d'Ivoire. Trans R Soc Trop Med Hyg 98 (2004) 18-27
46. Montero R., and Ostrosky P. Genotoxic activity of praziquantel. Mutat Res 387 (1997) 123-139
47. Meyer T., Sekljic H., Fuchs S., Bothe H., Schollmeyer D., and Miculka C. Taste, A new incentive to switch to (R)-praziquantel in schistosomiasis treatment. PLoS NTD 3 (2009) e357
48. WHO. Soil-transmitted helminthiasis: Progress report on number of children treated with anthelminthic drugs: an update towards the 2010 global target. Wkly Epidemiol Rec 2008; 83: 237-252.
49. Crawley MJ. Graphics. In: The R book. Chichester: Wiley; 2007, p. 135-82.