Pigment epithelium-derived factor inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1851, Issue 3, 2015, Pages 290-298

  Ibrahim, Ahmed S ^a,b   Tawfik, Amany M ^a   Hussein, Khaled A ^a   Elshafey, Sally ^a   Markand, Shanu ^a   Rizk, Nasser ^c   Duh, Elia J ^d   Smith, Sylvia B ^a   Al Shabrawey, Mohamed ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b MANSOURA UNIVERSITY   (Egypt)

^c Qatar University   (Qatar)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; APOCYNIN; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; HYDROXYICOSATETRAENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; PIGMENT EPITHELIUM DERIVED FACTOR; PROTEIN ZO1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; 12-15-LIPOXYGENASE; 15-HYDROXY-5,8,11,13-EICOSATETRAENOIC ACID; ACETOPHENONE DERIVATIVE; CYBB PROTEIN, MOUSE; EYE PROTEIN; IL6 PROTEIN, HUMAN; MEMBRANE PROTEIN; NERVE GROWTH FACTOR; PIGMENT EPITHELIUM-DERIVED FACTOR; SERINE PROTEINASE INHIBITOR; TJP1 PROTEIN, HUMAN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE RELEASE; DIABETES MELLITUS; DIABETIC RETINOPATHY; DRUG MECHANISM; DRUG TISSUE LEVEL; ENDOTHELIUM CELL; EYE PROTECTION; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; IN VITRO STUDY; MALE; MOUSE; MUELLER CELL; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA BLOOD VESSEL; RETINA CELL; RETINA FLUORESCEIN ANGIOGRAPHY; RETINA INJURY; RETINA NEOVASCULARIZATION; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; INTRAVITREAL DRUG ADMINISTRATION; KNOCKOUT MOUSE; MACROGLIA; METABOLISM; PATHOLOGY; RETINA; RETINAL NEOVASCULARIZATION;

MUS;

12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; ACETOPHENONES; ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; CELLS, CULTURED; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; ENDOTHELIAL CELLS; EPENDYMOGLIAL CELLS; EYE PROTEINS; GENE EXPRESSION REGULATION; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; INTRAVITREAL INJECTIONS; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; NADPH OXIDASE; NERVE GROWTH FACTORS; NF-KAPPA B; RETINA; RETINAL NEOVASCULARIZATION; SERPINS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84921057109     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2014.12.017     Document Type: Article

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