Pigment epithelium-derived factor (PEDF) peptide eye drops reduce inflammation, cell death and vascular leakage in diabetic retinopathy in Ins2(Akita) mice.

Molecular medicine (Cambridge, Mass.)

Volumn 18, Issue , 2012, Pages 1387-1401

  Liu, Yanling ^a   Leo, Lan Franco ^b   McGregor, Corban ^b   Grivitishvili, Anzor ^b   Barnstable, Colin J ^b   Tombran Tink, Joyce ^b  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

EYE DROPS; EYE PROTEIN; INS2 PROTEIN, MOUSE; INSULIN; MALEIMIDE DERIVATIVE; NERVE GROWTH FACTOR; PEPTIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PIGMENT EPITHELIUM DERIVED FACTOR; PIGMENT EPITHELIUM-DERIVED FACTOR; PROTEIN KINASE B; SERINE PROTEINASE INHIBITOR; TIGHT JUNCTION PROTEIN;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; C57BL MOUSE; CELL DEATH; CHEMISTRY; DIABETIC RETINOPATHY; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; FEMALE; GLIA; HUMAN; INFLAMMATION; ISOLATION AND PURIFICATION; MALE; METABOLISM; MOUSE; PATHOLOGY; RETINA BLOOD VESSEL; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION; VITREOUS BODY;

ANIMALS; CELL DEATH; DIABETIC RETINOPATHY; ENZYME ACTIVATION; EYE PROTEINS; FEMALE; HUMANS; INFLAMMATION; INSULIN; MALE; MALEIMIDES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; NERVE GROWTH FACTORS; NEUROGLIA; OPHTHALMIC SOLUTIONS; PEPTIDES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS, SPRAGUE-DAWLEY; RETINAL VESSELS; SERPINS; TIGHT JUNCTION PROTEINS; TISSUE DISTRIBUTION; VITREOUS BODY;

MLCS; MLOWN;

EID: 84877265732     PISSN: None     EISSN: 15283658     Source Type: None    
DOI: 10.2119/molmed.2012.00008     Document Type: Article

References (0)