Long-term retinal PEDF overexpression prevents neovascularization in a murine adult model of retinopathy

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Haurigot, Virginia ^a,b   Villacampa, Pilar ^a,b   Ribera, Albert ^a,b   Bosch, Assumpcio ^a   Ramos, David ^a   Ruberte, Jesus ^a   Bosch, Fatima ^a,b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; GELATINASE A; GELATINASE B; PARVOVIRUS VECTOR; PIGMENT EPITHELIUM DERIVED FACTOR; SOMATOMEDIN C; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTIANGIOGENIC GENE THERAPY; ARTICLE; CAPILLARY DENSITY; CONTROLLED STUDY; DIABETIC RETINOPATHY; DISEASE COURSE; DRUG EFFICACY; ENZYME ACTIVITY; GENE; GENE OVEREXPRESSION; HYPOXIA; MOUSE; NONHUMAN; PIGMENT EPITHELIUM DERIVED FACTOR GENE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RETINA DETACHMENT; RETINA NEOVASCULARIZATION; SINGLE DRUG DOSE; TRANSGENIC MOUSE;

AGING; ANIMALS; CELL HYPOXIA; DEPENDOVIRUS; DIABETIC RETINOPATHY; DISEASE MODELS, ANIMAL; DOWN-REGULATION; EYE PROTEINS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INSULIN-LIKE GROWTH FACTOR I; INTRAVITREAL INJECTIONS; MICE; MICE, TRANSGENIC; NERVE GROWTH FACTORS; RETINA; RETINAL DETACHMENT; RETINAL NEOVASCULARIZATION; SERPINS; TIME FACTORS; TRANSDUCTION, GENETIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

ANIMALIA; MURINAE;

EID: 84864078665     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041511     Document Type: Article

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