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Volumn 63, Issue 3, 2015, Pages 365-382

Expression of Gls and Gls2 glutaminase isoforms in astrocytes

Author keywords

Astrocytes; Glial cells; Glutamate; Glutaminase; Glutamine; Mitochondrion; Nucleus

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; GLS GLUTAMINASE; GLS2 GLUTAMINASE; GLUTAMINASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID; GLS1 PROTEIN, HUMAN; GLS2 PROTEIN, HUMAN; GLUTAMIC ACID; ISOENZYME; MESSENGER RNA;

EID: 84921024353     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22758     Document Type: Article
Times cited : (46)

References (70)
  • 1
    • 0025349011 scopus 로고
    • Distribution of phosphate-activated glutaminase in the human cerebral cortex
    • Akiyama H, Kaneko T, Mizuno N, McGeer PL. 1990. Distribution of phosphate-activated glutaminase in the human cerebral cortex. J Comp Neurol 297:239-252.
    • (1990) J Comp Neurol , vol.297 , pp. 239-252
    • Akiyama, H.1    Kaneko, T.2    Mizuno, N.3    McGeer, P.L.4
  • 2
    • 33750608704 scopus 로고    scopus 로고
    • Glutamine: A Trojan horse in ammonia neurotoxicity
    • Albrecht J, Norenberg MD. 2006. Glutamine: A Trojan horse in ammonia neurotoxicity. Hepatology 44:788-794.
    • (2006) Hepatology , vol.44 , pp. 788-794
    • Albrecht, J.1    Norenberg, M.D.2
  • 3
    • 0027509414 scopus 로고
    • Native polyacrylamide gel electrophoresis of membrane proteins: Glutaminase detection after in situ specific activity staining
    • Aledo JC, Gómez-Biedma S, Segura JA, Molina M, Núñez de Castro I, Márquez J. 1993. Native polyacrylamide gel electrophoresis of membrane proteins: Glutaminase detection after in situ specific activity staining. Electrophoresis 14:88-93.
    • (1993) Electrophoresis , vol.14 , pp. 88-93
    • Aledo, J.C.1    Gómez-Biedma, S.2    Segura, J.A.3    Molina, M.4    Núñez de Castro, I.5    Márquez, J.6
  • 4
    • 0033661413 scopus 로고    scopus 로고
    • Identification of two human glutaminase loci and tissue-specific expression of the two related genes
    • Aledo JC, Gómez-Fabre PM, Olalla L, Márquez J. 2000. Identification of two human glutaminase loci and tissue-specific expression of the two related genes. Mamm Genome 11:1107-1110.
    • (2000) Mamm Genome , vol.11 , pp. 1107-1110
    • Aledo, J.C.1    Gómez-Fabre, P.M.2    Olalla, L.3    Márquez, J.4
  • 6
    • 0022002929 scopus 로고
    • Immunocytochemical localization of glutaminase-like and aspartate aminotransferase-like immunoreactivities in the rat and guinea pig hippocampus
    • Altschuler RA, Monaghan DT, Haser WG, Wenthold RJ, Curthoys NP, Cotman CW. 1985. Immunocytochemical localization of glutaminase-like and aspartate aminotransferase-like immunoreactivities in the rat and guinea pig hippocampus. Brain Res 330:225-233.
    • (1985) Brain Res , vol.330 , pp. 225-233
    • Altschuler, R.A.1    Monaghan, D.T.2    Haser, W.G.3    Wenthold, R.J.4    Curthoys, N.P.5    Cotman, C.W.6
  • 8
    • 0025732188 scopus 로고
    • Identification of mitochondrial and non-mitochondrial glutaminase within select neurons and glia of rat forebrain by electron microscopic immunocytochemistry
    • Aoki C, Kaneko T, Starr A, Pickel VM. 1991. Identification of mitochondrial and non-mitochondrial glutaminase within select neurons and glia of rat forebrain by electron microscopic immunocytochemistry. J Neurosci Res 28:531-548.
    • (1991) J Neurosci Res , vol.28 , pp. 531-548
    • Aoki, C.1    Kaneko, T.2    Starr, A.3    Pickel, V.M.4
  • 9
    • 0031867098 scopus 로고    scopus 로고
    • Glutamate-dependent astrocyte modulation of synaptic transmission between cultured hippocampal neurons
    • Araque A, Parpura V, Sanzgiri RP, Haydon PG. 1998. Glutamate-dependent astrocyte modulation of synaptic transmission between cultured hippocampal neurons. Eur J Neurosci 10:2129-2142.
    • (1998) Eur J Neurosci , vol.10 , pp. 2129-2142
    • Araque, A.1    Parpura, V.2    Sanzgiri, R.P.3    Haydon, P.G.4
  • 11
    • 0034651087 scopus 로고    scopus 로고
    • SNARE protein-dependent glutamate release from astrocytes
    • Araque A, Li N, Doyle RT, Haydon PG. 2000. SNARE protein-dependent glutamate release from astrocytes. J Neurosci 20:666-673.
    • (2000) J Neurosci , vol.20 , pp. 666-673
    • Araque, A.1    Li, N.2    Doyle, R.T.3    Haydon, P.G.4
  • 13
    • 0141884303 scopus 로고    scopus 로고
    • Glial cells and neurotransmission: An inclusive view of synaptic function
    • Auld DS, Robitaille R. 2003. Glial cells and neurotransmission: An inclusive view of synaptic function. Neuron 40:389-400.
    • (2003) Neuron , vol.40 , pp. 389-400
    • Auld, D.S.1    Robitaille, R.2
  • 16
    • 0002887238 scopus 로고
    • The metabolic compartmentation concept
    • In: Hertz L, Kvamme E, McGeer EG, Schousboe A, editors. . New York: Alan R. Liss, Inc.
    • Berl S, Clarke DD. 1983. The metabolic compartmentation concept. In: Hertz L, Kvamme E, McGeer EG, Schousboe A, editors. Glutamine, glutamate and GABA in the central nervous system. New York: Alan R. Liss, Inc. pp 205-217.
    • (1983) Glutamine, glutamate and GABA in the central nervous system , pp. 205-217
    • Berl, S.1    Clarke, D.D.2
  • 17
  • 19
    • 0029099953 scopus 로고
    • Regulation of glutaminase activity and glutamine metabolism
    • Curthoys NP, Watford M. 1995. Regulation of glutaminase activity and glutamine metabolism. Annu Rev Nutr 15:133-159.
    • (1995) Annu Rev Nutr , vol.15 , pp. 133-159
    • Curthoys, N.P.1    Watford, M.2
  • 20
    • 0035001341 scopus 로고    scopus 로고
    • Glutamate uptake
    • Danbolt NC. 2001. Glutamate uptake. Prog Neurobiol 65:1-105.
    • (2001) Prog Neurobiol , vol.65 , pp. 1-105
    • Danbolt, N.C.1
  • 22
    • 0022377322 scopus 로고
    • Localization of glutaminase-like and aspartate aminotransferase-like immunoreactivity in neurons of cerebral neocortex
    • Donoghue JP, Wenthold RJ, Altschuler RA. 1985. Localization of glutaminase-like and aspartate aminotransferase-like immunoreactivity in neurons of cerebral neocortex. J Neurosci 5:2597-2608.
    • (1985) J Neurosci , vol.5 , pp. 2597-2608
    • Donoghue, J.P.1    Wenthold, R.J.2    Altschuler, R.A.3
  • 23
    • 0033620972 scopus 로고    scopus 로고
    • Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing
    • Elgadi KM, Meguid RA, Qian M, Souba WW, Abcouwer SF. 1999. Cloning and analysis of unique human glutaminase isoforms generated by tissue-specific alternative splicing. Physiol Genomics 1:51-62.
    • (1999) Physiol Genomics , vol.1 , pp. 51-62
    • Elgadi, K.M.1    Meguid, R.A.2    Qian, M.3    Souba, W.W.4    Abcouwer, S.F.5
  • 24
    • 0025196959 scopus 로고
    • Metabolism and role of glutamate in mammalian brain
    • Erecinska M, Silver IA. 1990. Metabolism and role of glutamate in mammalian brain. Prog Neurobiol 35:245-296.
    • (1990) Prog Neurobiol , vol.35 , pp. 245-296
    • Erecinska, M.1    Silver, I.A.2
  • 25
    • 33846896689 scopus 로고    scopus 로고
    • Co-localization of glutamic acid decarboxylase and phosphate-activated glutaminase in neurons of lateral reticular nucleus in feline thalamus
    • Fisher RS. 2007. Co-localization of glutamic acid decarboxylase and phosphate-activated glutaminase in neurons of lateral reticular nucleus in feline thalamus. Neurochem Res 32:177-186.
    • (2007) Neurochem Res , vol.32 , pp. 177-186
    • Fisher, R.S.1
  • 26
    • 25444479697 scopus 로고    scopus 로고
    • Cultures of rat astrocytes challenged with a steady supply of glutamate: New model to study flux distribution in the glutamate-glutamine cycle
    • Fonseca LL, Monteiro MAR, Alves PM, Carrondo MJT, Santos H. 2005. Cultures of rat astrocytes challenged with a steady supply of glutamate: New model to study flux distribution in the glutamate-glutamine cycle. Glia 51:286-296.
    • (2005) Glia , vol.51 , pp. 286-296
    • Fonseca, L.L.1    Monteiro, M.A.R.2    Alves, P.M.3    Carrondo, M.J.T.4    Santos, H.5
  • 28
    • 0018670663 scopus 로고
    • Functional interactions between neurons and astrocytes. I. Turnover and metabolism of putative amino acid transmitters
    • Hertz L. 1979. Functional interactions between neurons and astrocytes. I. Turnover and metabolism of putative amino acid transmitters. Prog Neurobiol 13:277-323.
    • (1979) Prog Neurobiol , vol.13 , pp. 277-323
    • Hertz, L.1
  • 29
    • 2442546861 scopus 로고    scopus 로고
    • Intercellular metabolic compartmentation in the brain: Past, present and future
    • Hertz L. 2004. Intercellular metabolic compartmentation in the brain: Past, present and future. Neurochem Int 45:285-296.
    • (2004) Neurochem Int , vol.45 , pp. 285-296
    • Hertz, L.1
  • 33
    • 0027931571 scopus 로고
    • Glutamate-synthesizing enzymes in GABAergic neurons of the neocortex: A double immunofluorescence study in the rat
    • Kaneko T, Mizuno N. 1994. Glutamate-synthesizing enzymes in GABAergic neurons of the neocortex: A double immunofluorescence study in the rat. Neuroscience 61:839-849.
    • (1994) Neuroscience , vol.61 , pp. 839-849
    • Kaneko, T.1    Mizuno, N.2
  • 34
    • 0026710370 scopus 로고
    • Paucity of glutaminase-immunoreactive non-pyramidal neurons in the rat cerebral cortex
    • Kaneko T, Nakaya Y, Mizuno N. 1992. Paucity of glutaminase-immunoreactive non-pyramidal neurons in the rat cerebral cortex. J Comp Neurol 322:181-190.
    • (1992) J Comp Neurol , vol.322 , pp. 181-190
    • Kaneko, T.1    Nakaya, Y.2    Mizuno, N.3
  • 35
    • 0019944222 scopus 로고
    • Properties of phosphate activated glutaminase in astrocytes cultured from mouse brain
    • Kvamme E, Svenneby G, Hertz L, Schousboe A. 1982. Properties of phosphate activated glutaminase in astrocytes cultured from mouse brain. Neurochem Res 7:761-770.
    • (1982) Neurochem Res , vol.7 , pp. 761-770
    • Kvamme, E.1    Svenneby, G.2    Hertz, L.3    Schousboe, A.4
  • 36
    • 0032890369 scopus 로고    scopus 로고
    • Postembedding immunogold labelling reveals subcellular localization and pathway-specific enrichment of phosphate activated glutaminase in rat cerebellum
    • Laake JH, Takumi Y, Eidet J, Torgner IA, Roberg B, Kvamme E, Ottersen OP. 1999. Postembedding immunogold labelling reveals subcellular localization and pathway-specific enrichment of phosphate activated glutaminase in rat cerebellum. Neuroscience 88:1137-1151.
    • (1999) Neuroscience , vol.88 , pp. 1137-1151
    • Laake, J.H.1    Takumi, Y.2    Eidet, J.3    Torgner, I.A.4    Roberg, B.5    Kvamme, E.6    Ottersen, O.P.7
  • 38
    • 33745988312 scopus 로고    scopus 로고
    • Neuron-glia metabolic coupling and plasticity
    • Magistretti PJ. 2006. Neuron-glia metabolic coupling and plasticity. J Exp Biol 209:2304-2311.
    • (2006) J Exp Biol , vol.209 , pp. 2304-2311
    • Magistretti, P.J.1
  • 39
    • 0035900592 scopus 로고    scopus 로고
    • Evidence for glutamate, in addition to acetylcholine and GABA, neurotransmitter synthesis in basal forebrain neurons projecting to the entorhinal cortex
    • Manns ID, Mainville L, Jones BE. 2001. Evidence for glutamate, in addition to acetylcholine and GABA, neurotransmitter synthesis in basal forebrain neurons projecting to the entorhinal cortex. Neuroscience 107:249-263.
    • (2001) Neuroscience , vol.107 , pp. 249-263
    • Manns, I.D.1    Mainville, L.2    Jones, B.E.3
  • 47
    • 0023322754 scopus 로고
    • Interactions between neurons and glia in glutamate/glutamine compartmentation
    • Nicklas WJ, Zeevalk G, Hyndman A. 1987. Interactions between neurons and glia in glutamate/glutamine compartmentation. Biochem Soc Trans 15:208-210.
    • (1987) Biochem Soc Trans , vol.15 , pp. 208-210
    • Nicklas, W.J.1    Zeevalk, G.2    Hyndman, A.3
  • 48
    • 0018382256 scopus 로고
    • Fine structural localization of glutamine synthetase in astrocytes of rat brain
    • Norenberg MD, Martínez-Hernández A. 1979. Fine structural localization of glutamine synthetase in astrocytes of rat brain. Brain Res 161:303-310.
    • (1979) Brain Res , vol.161 , pp. 303-310
    • Norenberg, M.D.1    Martínez-Hernández, A.2
  • 51
    • 0028080101 scopus 로고
    • Glutamate uptake into astrocytes stimulates aerobic glycolisis: A mechanism coupling neuronal activity to glucose utilization
    • Pellerin L, Magistretti P. 1994. Glutamate uptake into astrocytes stimulates aerobic glycolisis: A mechanism coupling neuronal activity to glucose utilization. Proc Natl Acad Sci USA 91:10625-10629.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10625-10629
    • Pellerin, L.1    Magistretti, P.2
  • 52
    • 68049143450 scopus 로고    scopus 로고
    • Tripartite synapses: Astrocytes process and control synaptic information
    • Perea G, Navarrete M, Araque A. 2009. Tripartite synapses: Astrocytes process and control synaptic information. Trends Neurosci 32:421-431.
    • (2009) Trends Neurosci , vol.32 , pp. 421-431
    • Perea, G.1    Navarrete, M.2    Araque, A.3
  • 53
    • 0347370301 scopus 로고    scopus 로고
    • Complexity and species variation of the kidney-type glutaminase gene
    • Porter LD, Ibrahim H, Taylor L, Curthoys NP. 2002. Complexity and species variation of the kidney-type glutaminase gene. Physiol Genomics 9:57-66.
    • (2002) Physiol Genomics , vol.9 , pp. 57-66
    • Porter, L.D.1    Ibrahim, H.2    Taylor, L.3    Curthoys, N.P.4
  • 54
    • 84896689426 scopus 로고    scopus 로고
    • Glutamine in the pathogenesis of hepatic encephalopathy: The trojan horse hypothesis revisited
    • Rama Rao KV, Norenberg MD. 2014. Glutamine in the pathogenesis of hepatic encephalopathy: The trojan horse hypothesis revisited. Neurochem Res 39:593-598.
    • (2014) Neurochem Res , vol.39 , pp. 593-598
    • Rama Rao, K.V.1    Norenberg, M.D.2
  • 56
    • 0033017989 scopus 로고    scopus 로고
    • Inhibition of glutamine transport in rat brain mitochondria by some amino acids and tricarboxylic acid cycle intermediates
    • Roberg B, Torgner IA, Kvamme E. 1999. Inhibition of glutamine transport in rat brain mitochondria by some amino acids and tricarboxylic acid cycle intermediates. Neurochem Res 24:811-816.
    • (1999) Neurochem Res , vol.24 , pp. 811-816
    • Roberg, B.1    Torgner, I.A.2    Kvamme, E.3
  • 57
    • 0033615021 scopus 로고    scopus 로고
    • In vivo nuclear magnetic resonance spectroscopy studies of the relationship between the glutamate-glutamine neurotransmitter cycle and functional neuroenergetics
    • Rothman DL, Sibson NR, Hyder F, Shen J, Behar KL, Shulman RG. 1999. In vivo nuclear magnetic resonance spectroscopy studies of the relationship between the glutamate-glutamine neurotransmitter cycle and functional neuroenergetics. Philos Trans R Soc Lond B 354:1165-1177.
    • (1999) Philos Trans R Soc Lond B , vol.354 , pp. 1165-1177
    • Rothman, D.L.1    Sibson, N.R.2    Hyder, F.3    Shen, J.4    Behar, K.L.5    Shulman, R.G.6
  • 59
    • 0344013138 scopus 로고    scopus 로고
    • High-yield isolation of murine microglia by mild trypsinization
    • Saura J, Tusell JM, Serratosa J. 2003. High-yield isolation of murine microglia by mild trypsinization. Glia 44:183-199.
    • (2003) Glia , vol.44 , pp. 183-199
    • Saura, J.1    Tusell, J.M.2    Serratosa, J.3
  • 60
    • 0018386655 scopus 로고
    • Phosphate activated glutaminase activity and glutamine uptake in primary cultures of astrocytes
    • Schousboe A, Hertz L, Svenneby G, Kvamme E. 1979. Phosphate activated glutaminase activity and glutamine uptake in primary cultures of astrocytes. J Neurochem 32:943-950.
    • (1979) J Neurochem , vol.32 , pp. 943-950
    • Schousboe, A.1    Hertz, L.2    Svenneby, G.3    Kvamme, E.4
  • 61
    • 84922395267 scopus 로고    scopus 로고
    • Glutamate synthesis has to be matched by its degradation: Where do all the carbons go?
    • Jul 2. [Epub ahead of print].
    • Sonnewald U. 2014. Glutamate synthesis has to be matched by its degradation: Where do all the carbons go? J Neurochem (Jul 2). doi:10.1111/jnc.12812. [Epub ahead of print].
    • (2014) J Neurochem
    • Sonnewald, U.1
  • 62
    • 0027338137 scopus 로고
    • Metabolism of [U-13C]glutamate in astrocytes studied by 13C NMR spectroscopy: Incorporation of more label into lactate than into glutamine demonstrates the importance of the tricarboxylic acid cycle
    • Sonnewald U, Westergaard N, Petersen SB, Unsgard G, Schousboe A. 1993. Metabolism of [U-13C]glutamate in astrocytes studied by 13C NMR spectroscopy: Incorporation of more label into lactate than into glutamine demonstrates the importance of the tricarboxylic acid cycle. J Neurochem 61:1179-1182.
    • (1993) J Neurochem , vol.61 , pp. 1179-1182
    • Sonnewald, U.1    Westergaard, N.2    Petersen, S.B.3    Unsgard, G.4    Schousboe, A.5
  • 63
    • 41049090828 scopus 로고    scopus 로고
    • Relative expression of mRNAs coding for glutaminase isoforms in CNS tissues and CNS tumors
    • Szeliga M, Matyja E, Obara M, Grajkowska W, Czernicki T, Albrecht J. 2008. Relative expression of mRNAs coding for glutaminase isoforms in CNS tissues and CNS tumors. Neurochem Res 33:808-813.
    • (2008) Neurochem Res , vol.33 , pp. 808-813
    • Szeliga, M.1    Matyja, E.2    Obara, M.3    Grajkowska, W.4    Czernicki, T.5    Albrecht, J.6
  • 64
    • 67650757162 scopus 로고    scopus 로고
    • Transfection with liver-type glutaminase (LGA) cDNA alteres gene expression and reduces viability, migration and proliferation of T98G glioma cells
    • Szeliga M, Obara-Michlewska M, Matyja E, Lazarczyk M, Lobo C, Hilgier W, Alonso F, Márquez J, Albrecht J. 2009. Transfection with liver-type glutaminase (LGA) cDNA alteres gene expression and reduces viability, migration and proliferation of T98G glioma cells. Glia 57:1014-1023.
    • (2009) Glia , vol.57 , pp. 1014-1023
    • Szeliga, M.1    Obara-Michlewska, M.2    Matyja, E.3    Lazarczyk, M.4    Lobo, C.5    Hilgier, W.6    Alonso, F.7    Márquez, J.8    Albrecht, J.9
  • 65
    • 33746354022 scopus 로고    scopus 로고
    • Tumor necrosis factor-α induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner
    • Takeuchi H, Jin S, Wang J, Zhang G, Kawanokuchi J, Kuno R, Sonobe Y, Mizuno T, Suzumura A. 2006. Tumor necrosis factor-α induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner. J Biol Chem 281:21362-21368.
    • (2006) J Biol Chem , vol.281 , pp. 21362-21368
    • Takeuchi, H.1    Jin, S.2    Wang, J.3    Zhang, G.4    Kawanokuchi, J.5    Kuno, R.6    Sonobe, Y.7    Mizuno, T.8    Suzumura, A.9
  • 66
    • 0142074877 scopus 로고    scopus 로고
    • Distribution and morphological characterization of phosphate-activated glutaminase-immunoreactive neurons in cat visual cortex
    • Van der Gucht E, Jacobs S, Kaneko T, Vandesande F, Arckens L. 2003. Distribution and morphological characterization of phosphate-activated glutaminase-immunoreactive neurons in cat visual cortex. Brain Res 988:29-42.
    • (2003) Brain Res , vol.988 , pp. 29-42
    • Van der Gucht, E.1    Jacobs, S.2    Kaneko, T.3    Vandesande, F.4    Arckens, L.5
  • 69
    • 0025744947 scopus 로고
    • Histochemistry of glutamate metabolizing enzymes in the rat cerebellar cortex
    • Wurdig S, Kugler P. 1991. Histochemistry of glutamate metabolizing enzymes in the rat cerebellar cortex. Neurosci Lett 130:165-168.
    • (1991) Neurosci Lett , vol.130 , pp. 165-168
    • Wurdig, S.1    Kugler, P.2
  • 70
    • 0023820776 scopus 로고
    • 15N]glutamine: Implications for the glutamine-glutamate cycle
    • 15N]glutamine: Implications for the glutamine-glutamate cycle. J Neurochem 51:843-850.
    • (1988) J Neurochem , vol.51 , pp. 843-850
    • Yudkoff, M.1    Nissim, I.2    Pleasure, D.3


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