Pentacyclic triterpenoids from spikes of Prunella vulgaris L. inhibit glycogen phosphorylase and improve insulin sensitivity in 3T3-L1 adipocytes

Phytotherapy Research

Volumn 29, Issue 1, 2015, Pages 73-79

  Yu, Qian ^a   Qi, Jin ^a   Wang, Lu ^a   Liu, Shou Jin ^b   Yu, Bo Yang ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b ANHUI UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Glycogen phosphorylase; Insulin sensitivity; Lamiaceae Labiatae; Pentacyclic triterpenoid; Prunella vulgaris L

Indexed keywords

2ALPHA,3ALPHA DIHYDROXYLURS 12 EN 28 OIC ACID; 2ALPHA,3BETA DIHYDROXYOLEAN 12 EN 28 OIC ACID; 2ALPHA,3BETA,19ALPHA TETRAHYDROXYURS 12 EN 28 OIC ACID 28BETA DEXTRO GLUCOPYRANOSIDE; 2ALPHA,3BETA,19ALPHA TRIHYDROXYURS 12 EN 28 OIC ACID; 2ALPHA,3BETA,19ALPHA TRIHYDROXYURS 12 EN 28 OIC ACID 28BETA DEXTRO GLUCOPYRANOSIDE; 2ALPHA,3BETA,19ALPHA TRIHYDROXYURS 12 EN 28 OIC ACID 28BETA DEXTRO GLUCOPYRANOSYL BETA DEXTRO GLUCOPYRANOSIDE; 2ALPHA,3BETA,24 TRIHYDROXYOLEAN 12 EN 28 OIC ACID; 2ALPHA,3BETA,24 TRIHYDROXYURS 12 EN 28 OIC ACID; 2ALPHA,3BETA,24 TRIHYDROXYURS 12 EN 28 OIC ACID 28BETA DEXTRO GLUCOPYRANOSIDE; 2ALPHA,3BETA,24 TRIHYDROXYURS 12(30) DIEN 28 OIC ACID; GLYCOGEN PHOSPHORYLASE; INSULIN; METHANOL; OLEANOLIC ACID; PENTACYCLIC TRITERPENE; PLANT MEDICINAL PRODUCT; PRUNELLA VULGARIS EXTRACT; ROTUNDIC ACID 28 O ALPHA DEXTRO GLUCOPYRANOSYL BETA DEXTRO GLUCOPYRANOSIDE; UNCLASSIFIED DRUG; URSOLIC ACID; VULGASIDE I; VULGASIDE II; ENZYME INHIBITOR; GLUCOSE; GLYCOSIDE;

3T3 CELL LINE; ADIPOCYTE; ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG STRUCTURE; ENZYME INHIBITION; GLUCOSE INTAKE; IC50; INSULIN SENSITIVITY; LAMIACEAE; MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PHYTOCHEMISTRY; PRUNELLA VULGARIS; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; INSULIN RESISTANCE; ISOLATION AND PURIFICATION; METABOLISM; PRUNELLA;

PRUNELLA VULGARIS;

3T3 CELLS; ADIPOCYTES; ANIMALS; ENZYME INHIBITORS; GLUCOSE; GLYCOGEN PHOSPHORYLASE; GLYCOSIDES; INSULIN RESISTANCE; MICE; MOLECULAR STRUCTURE; PENTACYCLIC TRITERPENES; PRUNELLA;

EID: 84920982986     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5228     Document Type: Article

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