Shed syndecan-1 translocates to the nucleus of cells delivering growth factors and inhibiting histone acetylation: A novel mechanism of tumor-host cross-talk

Journal of Biological Chemistry

Volumn 290, Issue 2, 2015, Pages 941-949

  Stewart, Mark D ^a   Ramani, Vishnu C ^a   Sanderson, Ralph D ^a,b  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; BONE; CHAINS; CROSSTALK; CYTOLOGY; SODIUM SULFATE; SULFUR COMPOUNDS; TUMORS;

BONE MARROW DERIVED STROMAL CELLS; BONE MARROW MICROENVIRONMENT; CONDITIONED MEDIUM; HEPATOCYTE GROWTH FACTOR; HISTONE ACETYLATION; HISTONE ACETYLTRANSFERASES; MULTIPLE MYELOMA; NUCLEAR TRANSLOCATIONS;

CELLS;

CHEMOKINE; CYTOKINE; GROWTH FACTOR; HEPARAN SULFATE; HEPARIN; HEPARIN LYASE; HISTONE; HISTONE ACETYLTRANSFERASE; PROTEOHEPARAN SULFATE; SCATTER FACTOR; SHED SYNDECAN 1; SODIUM CHLORATE; SYNDECAN 1; UNCLASSIFIED DRUG; HISTONE ACETYLTRANSFERASE PCAF; P300-CBP-ASSOCIATED FACTOR;

ANGIOGENESIS; ARTICLE; BONE MARROW CELL; CELL ADHESION; CELL GROWTH; CELL INVASION; CELL MOTILITY; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; HISTONE ACETYLATION; HOST CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; INTRACELLULAR SIGNALING; METASTASIS; MULTIPLE MYELOMA; PROTEIN PURIFICATION; STROMA CELL; TUMOR CELL; TUMOR GROWTH; ACETYLATION; BIOSYNTHESIS; BONE MARROW; CARCINOGENESIS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; TUMOR CELL LINE; TUMOR MICROENVIRONMENT;

ACETYLATION; BONE MARROW; CARCINOGENESIS; CELL LINE, TUMOR; CELL NUCLEUS; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONES; HUMANS; MULTIPLE MYELOMA; P300-CBP TRANSCRIPTION FACTORS; STROMAL CELLS; SYNDECAN-1; TUMOR MICROENVIRONMENT;

EID: 84920971198     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.608455     Document Type: Article

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