Sulfation patterns determine cellular internalization of heparin-like polysaccharides

Molecular Pharmaceutics

Volumn 10, Issue 4, 2013, Pages 1442-1449

  Raman, Karthik ^a   Mencio, Caitlin ^b   Desai, Umesh R ^c   Kuberan, Balagurunathan ^a,b,d  

^a Department of Electrical and Computer Engineering   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^d UNIVERSITY OF UTAH   (United States)

Author keywords

cellular uptake; heparan sulfate; heparin; heparosan; internalization; nucleus localization

Indexed keywords

HEPARAN SULFATE; HEPARIN; POLYSACCHARIDE;

ANION EXCHANGE CHROMATOGRAPHY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; FLOW CYTOMETRY; FLUORESCENCE; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTERNALIZATION; PRIORITY JOURNAL; REVIEW; SULFATION;

CELL LINE, TUMOR; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, ION EXCHANGE; DISACCHARIDES; DRUG DELIVERY SYSTEMS; ESCHERICHIA COLI; FLOW CYTOMETRY; HEPARIN; HUMANS; LIGANDS; MICROSCOPY, CONFOCAL; POLYSACCHARIDES; SULFUR; TIME FACTORS;

EID: 84875781718     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp300679a     Document Type: Review

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