Antiviral immunity of Anopheles gambiae is highly compartmentalized, with distinct roles for RNA interference and gut microbiota

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 2, 2015, Pages E176-E185

  Carissimo, Guillaume ^a,b,c   Pondeville, Emilie ^a,b,d   McFarlane, Melanie ^d   Dietrich, Isabelle ^d   Mitri, Christian ^a,b   Bischoff, Emmanuel ^a,b   Antoniewski, Christophe ^e   Bourgouin, Catherine ^a,b   Failloux, Anna Bella ^f   Kohl, Alain ^d   Vernick, Kenneth D ^a,b,g   Barillas Mury, Carolina ^h  

^a Department of Parasites and Insect Vectors Unit of Genetics and Genomics of Insect Vectors   (France)

^b CNRS   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d MRC UNIVERSITY OF GLASGOW CENTRE FOR VIRUS RESEARCH   (United Kingdom)

^e Université René Descartes   (France)

^f INSTITUT PASTEUR   (France)

^g UNIVERSITY OF MINNESOTA   (United States)

^h NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Arbovirus; Host pathogen interactions; Innate immunity; Insect immunity; Malaria

Indexed keywords

ANTIVIRUS AGENT; JANUS KINASE; LEUCINE; SMALL INTERFERING RNA; STAT PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ANOPHELES GAMBIAE; ANTIVIRAL ACTIVITY; ARTICLE; BACTERIAL FLORA; CELL ACTIVATION; COMPARATIVE STUDY; CONTROLLED STUDY; EXOGENOUS VARIABLE; FEMALE; GENE SILENCING; HUMAN; IMMUNE DEFICIENCY; IN VITRO STUDY; INTESTINE FLORA; NONHUMAN; O NYONG NYONG VIRUS; PARASITE IMMUNITY; PRIORITY JOURNAL; RNA INTERFERENCE; SIGNAL TRANSDUCTION; VIRUS INFECTION; VIRUS INFECTIVITY; VIRUS LOAD; VIRUS REPLICATION; ALPHAVIRUS INFECTION; ANIMAL; ARBOVIRUS; DIGESTIVE SYSTEM; DISEASE CARRIER; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; MICROBIOLOGY; MICROFLORA; PATHOGENICITY; PLASMODIUM FALCIPARUM; TRANSMISSION; VIROLOGY;

ANIMALIA; ANOPHELES GAMBIAE; ARBOVIRUS; ARTHROPODA; BACTERIA (MICROORGANISMS); HEXAPODA; O'NYONG-NYONG VIRUS;

ALPHAVIRUS INFECTIONS; ANIMALS; ANOPHELES GAMBIAE; ARBOVIRUS INFECTIONS; ARBOVIRUSES; DIGESTIVE SYSTEM; FEMALE; HOST-PATHOGEN INTERACTIONS; HUMANS; INSECT VECTORS; JANUS KINASES; MICROBIOTA; O'NYONG-NYONG VIRUS; PLASMODIUM FALCIPARUM; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS;

EID: 84920955342     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1412984112     Document Type: Article

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