Oxygen-glucose deprivation inducing B1 RNA inhibits neuronal cells metabolic activity by NLRP3 and associated proinflammatory cytokines production

Neuroscience Letters

Volumn 588, Issue , 2015, Pages 147-153

  Wang, Li ^a   Wang, Weihua ^b   Zhang, Lei ^a   Dai, Peng ^b   Wang, Kai ^a   Hui, Hao ^a   Rao, Wei ^a   Peng, Cheng ^a   Yang, Jinghua ^c   Yan, Zhen ^b   Fei, Zhou ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c VA BOSTON HEALTHCARE SYSTEM   (United States)

Author keywords

B1 RNA; Cerebral ischemia; DsRNA; NLRP3; Oxygen and glucose deprivation

Indexed keywords

CRYOPYRIN; DOUBLE STRANDED RNA; DOUBLE STRANDED RNA B1; DOUBLE STRANDED RNA B2; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; GLUCOSE; OXYGEN; RETROPOSON; RNA;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL ENERGY; CELL METABOLISM; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; DNA SEQUENCE; DOWN REGULATION; GENE SILENCING; HYPOXIA; MALE; NERVE CELL GROWTH; NONHUMAN; OXIDATIVE STRESS; OXYGEN AND GLUCOSE DEPRIVATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SEQUENCE; RNA TRANSCRIPTION; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL CULTURE; CEREBRAL ARTERY DISEASE; DEFICIENCY; GENETICS; METABOLISM; NERVE CELL; PATHOLOGY; PLASMID; RETROPOSON;

ANIMALS; CARRIER PROTEINS; CELLS, CULTURED; GLUCOSE; INFARCTION, MIDDLE CEREBRAL ARTERY; INTERLEUKIN-1BETA; MICE, INBRED BALB C; NEURONS; OXYGEN; PLASMIDS; RETROELEMENTS; RNA; RNA, DOUBLE-STRANDED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84920940790     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2014.12.045     Document Type: Article

References (17)

1. Brydges S.D., Broderick L., McGeough M.D., Pena C.A., Mueller J.L., Hoffman H.M. Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies. J. Clin. Invest. 2013, 123:4695-4705.
2. Choi J.S., Kim S.J., Shin J.A., Lee K.E., Park E.M. Effects of estrogen on temporal expressions of IL-1beta and IL-1ra in rat organotypic hippocampal slices exposed to oxygen-glucose deprivation. Neurosci. Lett. 2008, 438:233-237.
3. Cimarosti H., Henley J.M. Investigating the mechanisms underlying neuronal death in ischemia using in vitro oxygen-glucose deprivation: potential involvement of protein SUMOylation. Neurosci.: Rev. J. Bringing Neurobiol. Neurol. Psychiatry 2008, 14:626-636.
4. Codolo G., Plotegher N., Pozzobon T., Brucale M., Tessari I., Bubacco L., de Bernard M. Triggering of inflammasome by aggregated alpha-synuclein, an inflammatory response in synucleinopathies. PLoS 2013, 8:e55375.
5. Deininger P.L., Batzer M.A. Alu repeats and human disease. Mol. Genet. Metabol. 1999, 67:183-193.
6. Eyo U.B., Dailey M.E. Microglia: key elements in neural development, plasticity, and pathology. J. Neuroimmune Pharmacol.: Off. J. Soc. NeuroImmune Pharmacol. 2013, 8:494-509.
7. Fann D.Y., Lee S.Y., Manzanero S., Tang S.C., Gelderblom M., Chunduri P., Bernreuther C., Glatzel M., Cheng Y.L., Thundyil J., Widiapradja A., Lok K.Z., Foo S.L., Wang Y.C., Li Y.I., Drummond G.R., Basta M., Magnus T., Jo D.G., Mattson M.P., Sobey C.G., Arumugam T.V. Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke. Cell Death Dis. 2013, 4:e790.
8. Krayev A.S., Kramerov D.A., Skryabin K.G., Ryskov A.P., Bayev A.A., Georgiev G.P. The nucleotide sequence of the ubiquitous repetitive DNA sequence B1 complementary to the most abundant class of mouse fold-back RNA. Nucleic Acids Res. 1980, 8:1201-1215.
9. Lambertsen K.L., Biber K., Finsen B. Inflammatory cytokines in experimental and human stroke. J. Cereb. Blood Flow Metab.: Off. J. Int. Soc. Cereb. Blood Flow Metab. 2012, 32:1677-1698.
10. Lindsberg P.J., Soinne L., Roine R.O., Salonen O., Tatlisumak T., Kallela M., Happola O., Tiainen M., Haapaniemi E., Kuisma M., Kaste M. Thrombolytic therapy of cerebral infarction using alteplase - the Helsinki model. Duodecim Laaketieteellinen Aikakauskirja 2003, 119:1723-1729.
11. Lowe C.B., Bejerano G., Haussler D. Thousands of human mobile element fragments undergo strong purifying selection near developmental genes. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:8005-8010.
12. Nomura O., Yasue H. Genetic relationships among hippopotamus, whales, and bovine based on SINE insertion analysis. Mamm. Genome: Off. J. Int. Mamm. Genome Soc. 1999, 10:526-527.
13. Ponicsan S.L., Kugel J.F., Goodrich J.A. Genomic gems: SINE RNAs regulate mRNA production. Curr. Opin. Genet. Dev. 2010, 20:149-155.
14. Qi Y., Zhao M., Bai Y., Huang L., Yu W., Bian Z., Zhao M., Li X. Retinal ischemia/reperfusion injury is mediated by Toll-like receptor 4 activation of NLRP3 inflammasomes. Invest. Ophthalmol. Visual Sci. 2014, 55:5466-5475.
15. Tarallo V., Hirano Y., Gelfand B.D., Dridi S., Kerur N., Kim Y., Cho W.G., Kaneko H., Fowler B.J., Bogdanovich S., Albuquerque R.J., Hauswirth W.W., Chiodo V.A., Kugel J.F., Goodrich J.A., Ponicsan S.L., Chaudhuri G., Murphy M.P., Dunaief J.L., Ambati B.K., Ogura Y., Yoo J.W., Lee D.K., Provost P., Hinton D.R., Nunez G., Baffi J.Z., Kleinman M.E., Ambati J. DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell 2012, 149:847-859.
16. Wanderer A.A. Ischemic-reperfusion syndromes: biochemical and immunologic rationale for IL-1 targeted therapy. Clin. Immunol. 2008, 128:127-132.
17. Yakovchuk P., Goodrich J.A., Kugel J.F. B2 RNA and Alu RNA repress transcription by disrupting contacts between RNA polymerase II and promoter DNA within assembled complexes. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:5569-5574.