Aged iPSCs display an uncommon mitochondrial appearance and fail to undergo in vitro neurogenesis

Aging

Volumn 6, Issue 12, 2014, Pages 1094-1108

  Masotti, Andrea ^a   Celluzzi, Antonella ^a   Petrini, Stefania ^a   Bertini, Enrico ^a   Zanni, Ginevra ^a   Compagnucci, Claudia ^a  

^a BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

Author keywords

In vitro neurogenesis; Induced pluripotent stem cells; Mitochondria; Mitochondrial dysfunction; Stem cell aging

Indexed keywords

CELL AGING; CELL LINE; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; GENOTYPE; HUMAN; INDUCED PLURIPOTENT STEM CELL; METABOLISM; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; PATHOLOGY; PHENOTYPE; TIME FACTOR;

CELL AGING; CELL LINE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOTYPE; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL TURNOVER; NEURAL STEM CELLS; NEUROGENESIS; PHENOTYPE; TIME FACTORS; TRANSFECTION;

EID: 84920928909     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100708     Document Type: Article

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