Double-stranded RNA-specific adenosine deaminase 1 (ADAR1) promotes EIAV replication and infectivity

Virology

Volumn 476, Issue , 2015, Pages 364-371

  Tang, Yan Dong ^a,b   Na, Lei ^a   Fu, Li Hua ^a   Yang, Fei ^a   Zhu, Chun Hui ^a   Tang, Li ^a   Li, Qiang ^c   Wang, Jia Yi ^a   Li, Zhan ^a   Wang, Xue Feng ^a   Li, Cheng Yao ^b   Wang, Xiaojun ^a   Zhou, Jian Hua ^a,d  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c Harbin Weike Biotechnology Development Company   (China)

^d Harbin Pharmaceutical Group Biovaccine Company   (China)

Author keywords

ADAR1; EIAV; Infectivity; Replication

Indexed keywords

ADENOSINE DEAMINASE; ADENOSINE DEAMINASE 1; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; DOUBLE STRANDED RNA; UNCLASSIFIED DRUG; VIRUS RNA;

ARTICLE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; EQUINE INFECTIOUS ANEMIA VIRUS; LONG TERMINAL REPEAT; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REV RESPONSE ELEMENT; VIRUS INFECTIVITY; VIRUS REPLICATION; ANIMAL; CELL LINE; CHEMISTRY; ENZYMOLOGY; EQUINE INFECTIOUS ANEMIA; GENETICS; HORSE; HOST PATHOGEN INTERACTION; METABOLISM; PATHOGENICITY; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; VIROLOGY; VIRULENCE;

EQUIDAE; EQUINE INFECTIOUS ANEMIA VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; LENTIVIRUS; RETROVIRIDAE;

ADENOSINE DEAMINASE; ANIMALS; CELL LINE; EQUINE INFECTIOUS ANEMIA; HORSES; HOST-PATHOGEN INTERACTIONS; INFECTIOUS ANEMIA VIRUS, EQUINE; PROTEIN STRUCTURE, TERTIARY; RNA, DOUBLE-STRANDED; RNA, VIRAL; TERMINAL REPEAT SEQUENCES; VIRULENCE; VIRUS REPLICATION;

EID: 84920926965     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2014.12.038     Document Type: Article

References (37)

1. Bass B.L. RNA editing by adenosine deaminases that act on RNA. Annu. Rev. Biochem. 2002, 71:817-846.
2. Biswas N., Wang T., Ding M., Tumne A., Chen Y., Wang Q., Gupta P. ADAR1 is a novel multi targeted anti-HIV-1 cellular protein. Virology 2012, 422:265-277.
3. Casey J.L. RNA editing in hepatitis delta virus. Curr. Top. Microbiol. Immunol. 2006, 307:67-89.
4. Cattaneo R., Schmid A., Eschle D., Baczko K., ter Meulen V., Billeter M.A. Biased hypermutation and other genetic changes in defective measles viruses in human brain infections. Cell 1988, 55:255-265.
5. Clerzius G., Gelinas J.F., Daher A., Bonnet M., Meurs E.F., Gatignol A. ADAR1 interacts with PKR during human immunodeficiency virus infection of lymphocytes and contributes to viral replication. J. Virol. 2009, 83:10119-10128.
6. Clerzius G., Gelinas J.F., Gatignol A. Multiple levels of PKR inhibition during HIV-1 replication. Rev. Med. Virol. 2011, 21:42-53.
7. Cole J.L. Activation of PKR: an open and shut case?. Trends Biochem. Sci. 2007, 32:57-62.
8. Doria M., Tomaselli S., Neri F., Ciafre S.A., Farace M.G., Michienzi A., Gallo A. ADAR2 editing enzyme is a novel human immunodeficiency virus-1 proviral factor. J. Gen. Virol. 2011, 92:1228-1232.
9. Dorn P.L., Derse D. cis- and trans-acting regulation of gene expression of equine infectious anemia virus. J. Virol. 1988, 62:3522-3526.
10. Gelinas J.F., Clerzius G., Shaw E., Gatignol A. Enhancement of replication of RNA viruses by ADAR1 via RNA editing and inhibition of RNA-activated protein kinase. J. Virol. 2011, 85:8460-8466.
11. Gutierrez R.A., Viari A., Godelle B., Frutos R., Buchy P. Biased mutational pattern and quasispecies hypothesis in H5N1 virus. Infect., Genet. Evol.: J. Mol. Epidemiol. Evol. Genet. Infect. Dis. 2013, 15:69-76.
12. Ko N.L., Birlouez E., Wain-Hobson S., Mahieux R., Vartanian J.P. Hyperediting of human T-cell leukemia virus type 2 and simian T-cell leukemia virus type 3 by the dsRNA adenosine deaminase ADAR-1. J. Gen. Virol. 2012, 93:2646-2651.
13. Lecossier D., Bouchonnet F., Clavel F., Hance A.J. Hypermutation of HIV-1 DNA in the absence of the Vif protein. Science 2003, 300:1112.
14. Lee J.H., Culver G., Carpenter S., Dobbs D. Analysis of the EIAV Rev-responsive element (RRE) reveals a conserved RNA motif required for high affinity Rev binding in both HIV-1 and EIAV. PLoS One 2008, 3:e2272.
15. Leroux C., Cadore J.L., Montelaro R.C. Equine infectious anemia virus (EIAV): what has HIV's country cousin got to tell us?. Vet. Res. 2004, 35:485-512.
16. Li Z., Wolff K.C., Samuel C.E. RNA adenosine deaminase ADAR1 deficiency leads to increased activation of protein kinase PKR and reduced vesicular stomatitis virus growth following interferon treatment. Virology 2010, 396:316-322.
17. Lin Y.Z., Cao X.Z., Li L., Jiang C.G., Wang X.F., Ma J., Zhou J.H. The pathogenic and vaccine strains of equine infectious anemia virus differentially induce cytokine and chemokine expression and apoptosis in macrophages. Virus Res. 2011, 160:274-282.
18. Mangeat B., Turelli P., Caron G., Friedli M., Perrin L., Trono D. Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. Nature 2003, 424:99-103.
19. Martarano L., Stephens R., Rice N., Derse D. Equine infectious anemia virus trans-regulatory protein Rev controls viral mRNA stability, accumulation, and alternative splicing. J. Virol. 1994, 68:3102-3111.
20. Martinez I., Dopazo J., Melero J.A. Antigenic structure of the human respiratory syncytial virus G glycoprotein and relevance of hypermutation events for the generation of antigenic variants. J. Gen. Virol. 1997, 78(Pt 10):2419-2429.
21. Meng Q., Lin Y., Ma J., Ma Y., Zhao L., Li S., Liang H., Zhou J., Shen R., Zhang X., Shao Y. A pilot study on an attenuated Chinese EIAV vaccine inducing broadly neutralizing antibodies. Arch. Virol. 2011, 156:1455-1462.
22. Murphy D.G., Dimock K., Kang C.Y. Numerous transitions in human parainfluenza virus 3 RNA recovered from persistently infected cells. Virology 1991, 181:760-763.
23. Nie Y., Hammond G.L., Yang J.H. Double-stranded RNA deaminase ADAR1 increases host susceptibility to virus infection. J. Virol. 2007, 81:917-923.
24. Nishikura K. Functions and regulation of RNA editing by ADAR deaminases. Annu. Rev. Biochem. 2010, 79:321-349.
25. Pfaller C.K., Li Z., George C.X., Samuel C.E. Protein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon response. Curr. Opin. Immunol. 2011, 23:573-582.
26. Phuphuakrat A., Kraiwong R., Boonarkart C., Lauhakirti D., Lee T.H., Auewarakul P. Double-stranded RNA adenosine deaminases enhance expression of human immunodeficiency virus type 1 proteins. J. Virol. 2008, 82:10864-10872.
27. Sadler A.J., Williams B.R. Structure and function of the protein kinase R. Curr. Top. Microbiol. Immunol. 2007, 316:253-292.
28. Samuel C.E. Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral. Virology 2011, 411:180-193.
29. Suspene R., Petit V., Puyraimond-Zemmour D., Aynaud M.M., Henry M., Guetard D., Rusniok C., Wain-Hobson S., Vartanian J.P. Double-stranded RNA adenosine deaminase ADAR-1-induced hypermutated genomes among inactivated seasonal influenza and live attenuated measles virus vaccines. J. Virol. 2011, 85:2458-2462.
30. Tang Y.D., Na L., Zhu C.H., Shen N., Yang F., Fu X.Q., Wang Y.H., Fu L.H., Wang J.Y., Lin Y.Z., Wang X.F., Wang X., Zhou J.H., Li C.Y. Equine viperin restricts equine infectious anemia virus replication by inhibiting the production and/or release of viral Gag, Env and receptor by distorting the endoplasmic reticulum. J. Virol 2014.
31. Taylor D.R., Puig M., Darnell M.E., Mihalik K., Feinstone S.M. New antiviral pathway that mediates hepatitis C virus replicon interferon sensitivity through ADAR1. J. Virol. 2005, 79:6291-6298.
32. Wang X., Wang S., Lin Y., Jiang C., Ma J., Zhao L., Lv X., Wang F., Shen R., Kong X., Zhou J. Genomic comparison between attenuated Chinese equine infectious anemia virus vaccine strains and their parental virulent strains. Arch. Virol. 2011, 156:353-357.
33. Ward S.V., George C.X., Welch M.J., Liou L.Y., Hahm B., Lewicki H., de la Torre J.C., Samuel C.E., Oldstone M.B. RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:331-336.
34. Wu J., Chen Z.J. Innate immune sensing and signaling of cytosolic nucleic acids. Annu. Rev. Immunol. 2014, 32:461-488.
35. Yin X., Hu Z., Gu Q., Wu X., Zheng Y.H., Wei P., Wang X. Equine tetherin blocks retrovirus release and its activity is antagonized by equine infectious anemia virus envelope protein. J. Virol. 2014, 88:1259-1270.
36. Zahn R.C., Schelp I., Utermohlen O., von Laer D. A-to-G hypermutation in the genome of lymphocytic choriomeningitis virus. J. Virol. 2007, 81:457-464.
37. Zhang H., Yang B., Pomerantz R.J., Zhang C., Arunachalam S.C., Gao L. The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. Nature 2003, 424:94-98.