Cyclosporine-mediated allograft fibrosis is associated with micro-RNA-21 through AKT signaling

Transplant International

Volumn 28, Issue 2, 2015, Pages 232-245

  Chen, Jianguo ^a   Zmijewska, Anna ^a   Zhi, Degui ^b   Mannon, Roslyn B ^a  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

cyclosporine; fibrosis; microRNA; nephrotoxicity; signaling; transplantation

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CYCLOSPORIN A; MICRORNA 21; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; VIMENTIN; CALCINEURIN INHIBITOR; CYCLOSPORIN; MICRORNA; MIRN21 MICRORNA, HUMAN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EPIGENETICS; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; GENE; GENETIC ASSOCIATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; KIDNEY FIBROSIS; KIDNEY TUBULE EPITHELIUM; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; ALLOGRAFT; ANIMAL; CELL CULTURE; DRUG EFFECTS; FIBROSIS; KIDNEY; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY;

ALLOGRAFTS; ANIMALS; CALCINEURIN INHIBITORS; CELLS, CULTURED; CYCLOSPORINE; EPITHELIAL-MESENCHYMAL TRANSITION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROSIS; HUMANS; KIDNEY; MICE; MICRORNAS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84920919104     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/tri.12471     Document Type: Article

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