The frequency of invariant natural killer T cells correlates with the severity of myocarditis

Viral Immunology

Volumn 27, Issue 3, 2014, Pages 88-95

  Wang, Xinggang ^a   Li, Minghui ^a   Xie, Yeqing ^a   Yu, Ying ^a   Liu, Guijian ^a   Yu, Yong ^a   Yang, Xiangdong ^a   Zou, Yunzeng ^a   Ge, Junbo ^a   Chen, Ruizhen ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN VP1; CD3 ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD3+ T LYMPHOCYTE; CELL INFILTRATION; CONTROLLED STUDY; COXSACKIE VIRUS B3; COXSACKIE VIRUS INFECTION; DISEASE SEVERITY; HEART MUSCLE INJURY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INVARIANT NATURAL KILLER T CELL; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; SPLEEN; VIRUS MYOCARDITIS; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; BLOOD; CHEMISTRY; COMPLICATION; CYTOCHEMISTRY; DISEASE MODEL; ENTEROVIRUS; HEART MUSCLE; HUMAN; IMMUNOLOGY; MYOCARDITIS; PATHOLOGY; SEVERITY OF ILLNESS INDEX; VIROLOGY;

ANIMALS; ANTIGENS, CD3; BLOOD; COXSACKIEVIRUS INFECTIONS; DISEASE MODELS, ANIMAL; ENTEROVIRUS B, HUMAN; HISTOCYTOCHEMISTRY; HUMANS; MICE; MICE, INBRED BALB C; MYOCARDITIS; MYOCARDIUM; NATURAL KILLER T-CELLS; SEVERITY OF ILLNESS INDEX; SPLEEN;

EID: 84920871192     PISSN: 08828245     EISSN: 15578976     Source Type: Journal    
DOI: 10.1089/vim.2013.0078     Document Type: Article

References (24)

1. Chuang Y-P, Wang C-H, Wang N-C, et al. 2012 Modulatory function of invariant natural killer T cells in systemic lupus erythematosus. Clin Dev Immunol 2012; 2012:8.
2. Cooper LT, Jr. Myocarditis. N Engl J Med 2009;360:1526-1538.
3. Elamm C, Fairweather D, and Cooper LT. Republished: Pathogenesis and diagnosis of myocarditis. Postgrad Med J 2012;88:539-544.
4. Gupta S, Markham DW, Drazner MH, and Mammen PPA. Fulminant myocarditis. Nature Clin Pract Cardiovasc Med 2008;5:693-706.
5. Huber SA, Roberts B, Moussawi M, and Boyson JE. Slam haplotype 2 promotes NKT but suppresses V gamma 4( + ) T-cell activation in coxsackievirus B3 infection leading to increased liver damage but reduced myocarditis. Am J Pathol 2013;182:401-409.
6. Huber S, Sartini D, and Exley M. Role of CD1d in coxsackievirus B3-induced myocarditis. J Immunol 2003;170: 3147-3153.
7. Jung S, Shin H-S, Hong C, et al. Natural killer T cells promote collagen-induced arthritis in DBA/1 mice. Biochem Biophys Res Commun 2009;390:399-403.
8. Kindermann I, Barth C, Mahfoud F, et al. Update on myocarditis. J Am Coll Cardiol 2012;59:779-792.
9. Li M, Wang X, Xie Y, et al. Initial weight and virus dose: Two factors affecting the onset of acute coxsackievirus B3 myocarditis in C57BL/6 mouse-A histopathology-based study. Cardiovasc Pathol 2013;22:96-101.
10. Li YW, Bourlet T, Andreoletti L, et al. Enteroviral capsid protein VP1 is present in myocardial tissues from some patients with myocarditis or dilated cardiomyopathy. Circulation 2000;101:231-234.
11. Liu W, Moussawi M, Roberts B, et al. Cross-regulation of T regulatory-cell response after coxsackievirus B3 infection by NKT and gammadelta T cells in the mouse. Am J Pathol 2013;183:441-449.
12. Marchant DJ, and McManus BM. Regulating viral myocarditis: Allografted regulatory T cells decrease immune infiltration and viral load. Circulation 2010;121:2609-2611.
13. Martinez NE, Sato F, Kawai E, et al. Regulatory T cells and Th17 cells in viral infections: Implications for multiple sclerosis and myocarditis. Future Virol 2012;7:593-608.
14. Mattarollo SR, Steegh K, Li M, et al. Transient Foxp(3 + ) regulatory T-cell depletion enhances therapeutic anticancer vaccination targeting the immune-stimulatory properties of NKT cells. Immunol Cell Biol 2013;91:105-114.
15. Miletic A, Krmpotic A, and Jonjic S. The evolutionary arms race between NK cells and viruses: Who gets the short end of the stick? Eur J Immunol 2013;43:867-877.
16. Ohtaki H, H Ito, K Ando, et al. V alpha 14 NKT cells activated by alpha-galactosylceramide augment lipopolysaccharide- induced nitric oxide production in mouse intrahepatic lymphocytes. Biochem Biophys Res Commun 2009;378:579-583.
17. Papageorgiou A-P, Swinnen M, Vanhoutte D, et al. Thrombospondin-2 prevents cardiac injury and dysfunction in viral myocarditis through the activation of regulatory Tcells. Cardiovasc Res 2012;94:115-124.
18. Parekh VV, Wu L, Olivares-Villagomez D, et al. Activated invariant NKT cells control central nervous system autoimmunity in a mechanism that involves myeloid-derived suppressor cells. J Immunol 2013;190:1948-1960.
19. Tamura Y, Teng A, Nozawa R, et al. Characterization of the immature dendritic cells and cytotoxic cells both expanded after activation of invariant NKT cells with alphagalactosylceramide in vivo. Biochem Biophys Res Commun 2008;369:485-492.
20. Watarai H, Nakagawa R, Omori-Miyake M, et al. Methods for detection, isolation and culture of mouse and human invariant NKT cells. Nature Protocols 2008;3:70-78.
21. Wu CY, Feng Y, Qian GC, et al. alpha-Galactosylceramide protects mice from lethal Coxsackievirus B3 infection and subsequent myocarditis. Clin Exp Immunol 2010;162:178-187.
22. Xie Y, Chen R, Zhang X, et al. The role of Th17 cells and regulatory T cells in Coxsackievirus B3-induced myocarditis. Virology 2011;421:78-84.
23. Xie Y, Chen R, Zhang X, et al. Blockade of interleukin- 17A protects against coxsackievirus B3-induced myocarditis by increasing COX-2/PGE2 production in the heart. FEMS Immunol Med Microbiol 2012;64:343-351.
24. Zygmunt BM, Weissmann SF, Guzman CA. NKT cell stimulation with alpha-galactosylceramide results in a block of Th17 differentiation after intranasal immunization in mice. PLoS One 2012;7:e30382-e30382.