Thrombospondin-2 prevents cardiac injury and dysfunction in viral myocarditis through the activation of regulatory T-cells

Cardiovascular Research

Volumn 94, Issue 1, 2012, Pages 115-124

  Papageorgiou, Anna Pia ^a,b   Swinnen, Melissa ^b   Vanhoutte, Davy ^b   Vandendriessche, Thierry ^b,c   Chuah, Marinee ^b,c   Lindner, Diana ^d   Verhesen, Wouter ^a   De Vries, Bart ^e   Dhooge, Jan ^b   Lutgens, Esther ^f,g   Westermann, Dirk ^d   Carmeliet, Peter ^b,h   Heymans, Stephane ^a,b,i  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e MAASTRICHT UNIVERSITY   (Netherlands)

^f UNIVERSITY OF AMSTERDAM   (Netherlands)

^g LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^h DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

ⁱ ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

Author keywords

Inflammation; Matrix; Myocarditis; Regulatory T cells; Viruses

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; PARVOVIRUS VECTOR; THROMBOSPONDIN 2; TRANSCRIPTION FACTOR FOXP3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COXSACKIE VIRUS B3; GENE EXPRESSION; HEART DILATATION; HEART DISEASE; HEART INJURY; HEART MUSCLE FIBROSIS; HUMAN; HUMAN TISSUE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; VIRUS MYOCARDITIS; WILD TYPE;

ANIMALS; CTLA-4 ANTIGEN; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; ENTEROVIRUS B, HUMAN; FIBROSIS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, 129 STRAIN; MICE, INBRED C3H; MICE, KNOCKOUT; MYOCARDIAL CONTRACTION; MYOCARDITIS; MYOCARDIUM; NECROSIS; RNA, MESSENGER; T-LYMPHOCYTES, REGULATORY; THROMBOSPONDINS; TIME FACTORS; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT;

EID: 84859065715     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvs077     Document Type: Article

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