Blockade of lipid accumulation by silibinin in adipocytes and zebrafish

Chemico-Biological Interactions

Volumn 227, Issue , 2015, Pages 53-62

  Suh, Hyung Joo ^a   Cho, So Young ^a   Kim, Eun Young ^a   Choi, Hyeon Son ^b  

^a Korea University   (South Korea)

^b Seoul Women University   (South Korea)

Author keywords

3T3 L1; Adipogenesis; AMPK ; Cell cycle arrest; Silibinin; Zebrafish

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; CURCUMIN; CYCLINE; FATTY ACID BINDING PROTEIN 4; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE ALPHA; KRUPPEL LIKE FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLACEBO; PROTEIN KINASE B; PROTEIN P27; SILIBININ; UNCLASSIFIED DRUG; ANTIOXIDANT; CYCLIN DEPENDENT KINASE INHIBITOR 1B; FATTY ACID BINDING PROTEIN; KRUPPEL LIKE FACTOR; SILYMARIN;

ADIPOCYTE; ADIPOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE CHECKPOINT; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATIONAL STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG TARGETING; ENZYME INACTIVATION; FATTY ACID SYNTHESIS; G0 PHASE CELL CYCLE CHECKPOINT; G1 PHASE CELL CYCLE CHECKPOINT; IN VIVO STUDY; LARVAL STAGE; LIPID STORAGE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LIPID INTERACTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; UPREGULATION; ZEBRA FISH; 3T3 CELL LINE; ANIMAL; ANIMAL EMBRYO; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; GENETICS; GROWTH, DEVELOPMENT AND AGING; LARVA; LIPID METABOLISM; METABOLISM; MOUSE;

DANIO RERIO; SILYBUM MARIANUM;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; ANIMALS; ANTIOXIDANTS; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE INHIBITOR P27; EMBRYO, NONMAMMALIAN; FATTY ACID-BINDING PROTEINS; G1 PHASE CELL CYCLE CHECKPOINTS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LARVA; LIPID METABOLISM; MICE; PPAR GAMMA; SIGNAL TRANSDUCTION; SILYMARIN; ZEBRAFISH;

EID: 84920836502     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2014.12.027     Document Type: Article

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