Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family

RNA Biology

Volumn 11, Issue 8, 2014, Pages 1072-1082

  Hrle, Ajla ^a   Maier, Lisa Katharina ^b   Sharma, Kundan ^c   Ebert, Judith ^a   Basquin, Claire ^a   Urlaub, Henning ^c,d   Marchfelder, Anita ^b   Conti, Elena ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b UNIVERSITY OF ULM   (Germany)

^c MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^d UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

Cas7; CRISPR; Prokaryotic immune system; RNA binding; RRM domain

Indexed keywords

CAS7 PROTEIN; CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN; CRISPR ASSOCIATED PROTEIN; CSC2 PROTEIN; SINGLE STRANDED RNA; UNCLASSIFIED DRUG; ZINC BINDING PROTEIN; ARCHAEAL PROTEIN; ARCHAEAL RNA; RNA BINDING PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; IN VITRO STUDY; MASS SPECTROMETRY; NONHUMAN; PROTEIN ANALYSIS; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN STRUCTURE; RNA BINDING; RNA INTERFERENCE; THERMOFILUM; THERMOFILUM PENDENS; ARCHAEON; BINDING SITE; CHEMISTRY; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENETICS; HOST PATHOGEN INTERACTION; PROTEIN CONFORMATION; THERMOFILACEAE; X RAY CRYSTALLOGRAPHY;

PROKARYOTA; THERMOFILUM PENDENS;

ARCHAEA; ARCHAEAL PROTEINS; BINDING SITES; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-ASSOCIATED PROTEINS; CRYSTALLOGRAPHY, X-RAY; HOST-PATHOGEN INTERACTIONS; PROTEIN CONFORMATION; RNA, ARCHAEAL; RNA-BINDING PROTEINS; THERMOFILACEAE;

EID: 84920797201     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.4161/rna.29893     Document Type: Article

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