NMR profiling of biomolecules at natural abundance using 2D1H-15N and1H-13C multiplicity-separated (MS) HSQC spectra

Journal of Magnetic Resonance

Volumn 251, Issue , 2015, Pages 65-70

  Chen, Kang ^a   Freedberg, Darón I ^a   Keire, David A ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

MS HSQC; Multiplicity editing; Natural abundance; Triple axis gradient water suppression

Indexed keywords

BIOMOLECULES; CHEMICAL SHIFT; DISSOLUTION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEINS; SEPARATION; SIGNAL TO NOISE RATIO; SPECTROMETERS;

DEUTERATED SOLVENTS; MS-HSQC; MULTIPLICITY EDITING; NATURAL ABUNDANCE; NMR SPECTROMETER; PROTEIN THERAPEUTICS; ROOM TEMPERATURE; WATER SUPPRESSION;

NUCLEAR MAGNETIC RESONANCE;

MIRIDAE;

CARBON; DEUTERIUM; NITROGEN; PANCREATIC RIBONUCLEASE; PROTEIN; WATER;

ALGORITHM; CHEMISTRY; NUCLEAR MAGNETIC RESONANCE; PROCEDURES;

ALGORITHMS; CARBON ISOTOPES; DEUTERIUM; NITROGEN ISOTOPES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEINS; RIBONUCLEASE, PANCREATIC; WATER;

EID: 84920760529     PISSN: 10907807     EISSN: 10960856     Source Type: Journal    
DOI: 10.1016/j.jmr.2014.11.011     Document Type: Article

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