Reduced expressionof GDF-15 is associated with atrophic inflammatory lesions of the prostate

Prostate

Volumn 75, Issue 3, 2015, Pages 255-265

  Lambert, James R ^a   Whitson, Ramon J ^a,b   Iczkowski, Kenneth A ^a,c   La Rosa, Francisco G ^a   Smith, Maxwell L ^a,d   Wilson, R Storey ^a   Smith, Elizabeth E ^a   Torkko, Kathleen C ^a   Gari, Hamid H ^a   Lucia, M Scott ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

^d MAYO CLINIC   (United States)

Author keywords

GDF 15; Inflammation; Macrophage; NF B

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CHLORDANE; GROWTH DIFFERENTIATION FACTOR 15; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; LEUKOCYTE ANTIGEN;

ARTICLE; COMPUTER ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; DOWN REGULATION; EPITHELIUM CELL; GENE REPRESSION; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INFLAMMATORY CELL; LEUKOCYTE; LUCIFERASE ASSAY; MALE; PRIORITY JOURNAL; PROSTATE DISEASE; PROSTATE INFLAMMATION; PROSTATECTOMY; PROTEIN EXPRESSION; ATROPHY; METABOLISM; PATHOLOGY; PROSTATE; PROSTATITIS;

ANTIGENS, CD; ATROPHY; GROWTH DIFFERENTIATION FACTOR 15; HUMANS; MALE; NF-KAPPA B; PROSTATE; PROSTATITIS;

EID: 84920740809     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.22911     Document Type: Article

References (32)

1. Seigel R, Ma J, Jemal A. Cancer statistics, 2014. CA Cancer J Clin 2014; 64: 9-29.
2. De Marzo AM, Nakai Y, Nelson WG. Inflammation, atrophy, and prostate carcinogenesis. Urol Oncol 2007; 25: 398-400.
3. Nelson WG, De Marzo AM, DeWeese TL, Isaacs WB. The role of inflammation in the pathogenesis of prostate cancer. J Urol 2004; 172: s6-11 discussion S11-12.
4. Bosetti C, Rosato V, Gallus S, La Vecchia C. Aspirin and urologic cancer risk: an update. Nat Rev Urol 2012; 9: 102-110.
5. Jacobs EJ, Rodriguez C, Mondul AM, Connell CJ, Henley SJ, Calle EE, Thun MJ. A large cohort study of aspirin and othernonsteroidal anti-inflammatory drugs and prostate cancer incidence. J Natl Cancer Inst 2005; 97: 975-980.
6. Nelson WG, DeWeese TL, DeMarzo AM. The diet, prostate inflammation, and the development of prostate cancer. Cancer Metastasis Rev 2002; 21: 3-16.
7. Lucia MS, Lambert JR, Platz EA, De Marzo AM. Inflammation as a target in prostate cancer. In: Figg WD, Chau CH, Small EJ, editors. Drug management of prostate cancer. New York: Springer; 2010. pp. 375-386.
8. Shih VF, Tsui R, Caldwell A, Hoffmann A. A single NFkappaB system for both canonical and non-canonical signaling. Cell Res 2011; 21: 86-102.
9. Nogueira L, Ruiz-Ontanon P, Vazquez-Barquero A, Moris F, Fernandez-Luna JL. The NFkappaB pathway: A therapeutic target in glioblastoma. Oncotarget 2011; 2: 646-653.
10. Andela VB, Gordon AH, Zotalis G, Rosier RN, Goater JJ, Lewis GD, Schwarz EM, Puzas JE, O'Keefe RJ. NFkappa B: A pivotal transcription factor in prostate cancer metastasis to bone. Clin Orthop Relat Res 2003; 415 (Suppl.): S75-85.
11. Lu T, Stark GR. Cytokine overexpression and constitutive NFkappaB in cancer. Cell Cycle 2004; 3: 1114-1117.
12. Vykhovanets EV, Shankar E, Vykhovanets OV, Shukla S, Gupta S. High-fat diet increases NF-kappaB signaling in the prostate of reporter mice. Prostate 2011; 71: 147-156.
13. Bootcov MR, Bauskin AR, Valenzuela SM, Moore AG, Bansal M, He XY, Zhang HP, Donnellan M, Mahler S, Pryor K, Walsh BJ, Nicholson RC, Fairlie WD, Por SB, Robbins JM, Breit SN. MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily. Proc Natl Acad Sci USA 1997; 94: 11514-11519.
14. Baek SJ, Kim KS, Nixon JB, Wilson LC, Eling TE. Cyclooxygenase inhibitors regulate the expression of a TGF-beta superfamily member that has proapoptotic and antitumorigenic activities. Mol Pharmacol 2001; 59: 901-908.
15. Wynne S, Djakiew D. NSAID inhibition of prostate cancer cell migration is mediated by Nag-1 Induction via the p38 MAPKp75 ( NTR) pathway. Mol Cancer Res 2010; 8: 1656-1664.
16. Lambert JR, Kelly JA, Shim M, Huffer WE, Nordeen SK, Baek SJ, Eling TE, Lucia MS. Prostate derived factor in human prostate cancer cells: Gene induction by vitamin D via a p53-dependent mechanism and inhibition of prostate cancer cell growth. J Cell Physiol 2006; 208: 566-574.
17. Livak KJ, Schmittgen TD. Analysis of reltive gene expression data using real-time quantitative PCR and the 2 (-delta delta C (T)) method. Methods 2001; 25 (4): 402-408.
18. Vanhara P, Lincova E, Kozubik A, Jurdic P, Soucek K, Smarda J. Growth/differentiation factor-15 inhibits differentiation into osteoclasts-A novel factor involved in control of osteoclast differentiation. Differentiation 2009; 78: 213-222.
19. Wang X, Kingsley PJ, Marnett LJ, Eling TE. The role of NAG-1/ GDF15 in the inhibition of intestinal polyps in APC/Min mice by sulindac. Cancer Prev Res (Phila) 2011; 4: 150-160.
20. Cassatella MA, Bazzoni F, Ceska M, Ferro I, Baggiolini M, Berton G. IL-8 production by human polymorphonuclear leukocytes. The chemoattractant formyl-methionyl-leucylphenylalanine induces the gene expression and release of IL-8 through a pertussis toxin-sensitive pathway. J Immunol 1992; 148: 3216-3220.
21. Larsen CG, Anderson AO, Appella E, Oppenheim JJ, Matsushima K. The neutrophil-activating protein (NAP-1) is also chemotactic for T lymphocytes. Science 1989; 243: 1464-1466.
22. Kempf T, Zarbock A, Widera C, Butz S, Stadtmann A, Rossaint J, Bolomini-Vittori M, Korf-Klingebiel M, Napp LC, Hansen B, Kanwischer A, Bavendiek U, Beutel G, Hapke M, Sauer MG, Laudanna C, Hogg N, Vestweber D, Wollert KC. GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice. Nat Med 2011; 17: 581-588.
23. Nazarova N, Qiao S, Golovko O, Lou YR, Tuohimaa P. Calcitriol-induced prostate-derived factor: Autocrine control of prostate cancer cell growth. Int J Cancer 2004; 112: 951-958.
24. Baek SJ, Wilson LC, Eling TE. Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the expression of p53. Carcinogenesis 2002; 23: 425-434.
25. Lee SH, Kim JS, Yamaguchi K, Eling TE, Baek SJ. Indole-3-carbinol and 3,30-diindolylmethane induce expression of NAG-1 in a p53-independent manner. Biochem Biophys Res Commun 2005; 328: 63-69.
26. Appierto V, Villani MG, Cavadini E, Gariboldi M, De CI, Pierotti MA, Lambert JR, Reid J, Tiberio P, Colombo N, Formelli F. Analysis of gene expression identifies PLAB as a mediator of the apoptotic activity of fenretinide in human ovarian cancer cells. Oncogene 2007; 26: 3952-3962.
27. Soto-Cerrato V, Vinals F, Lambert JR, Kelly JA, Perez-Tomas R. Prodigiosin induces the proapoptotic gene NAG-1 via glycogen synthase kinase-3beta activity in human breast cancer cells. Mol Cancer Ther 2007; 6: 362-369.
28. Newman D, Sakaue M, Koo JS, Kim KS, Baek SJ, Eling TE, Jetten AM. Differential regulation of nonsteroidal anti-inflammatory drug-activated gene in normal human tracheobronchial epithelial and lung carcinoma cells by retinoids. Mol Pharmacol 2003; 63: 766-772.
29. Lee SH, Yamaguchi K, Kim JS, Eling TE, Safe S, Park Y, Baek SJ. Conjugated linoleic acid stimulates and anti-tumorigenic protein NAG-1 in an isomer specific manner. Carcinogenesis 2006; 27: 972-981.
30. Chen SJ, Karan D, Johansson SL, Lin FF, Zeckser J, Singh AP, Batra SK, Lin MF. Prostate derived factor as a paracrine and autocrine factor for the proliferation of androgen receptorpositive human prostate cancer cells. Prostate 2007; 67: 557-571.
31. Selander KS, Brown DA, Sequeiros GB, Hunter M, Desond R, Parpala T, Risteli J, Breit SN, Jukkola-Vuorinen A. Serum macrophage inhibitory cytokine-1 concentrations correlate with the presence of prostate cancer bone metastases. Cancer Epidemiol Biomarkers Prev 2007; 16: 532-537.
32. Brown DA, Stephan C, Ward RL, Law M, Hunter M, Bauskin AR, Amin J, Jung K, Diamandis EP, Hampton GM, Russell PJ, Giles GG, Breit SN. Measurement of serum levels of macrophage inhibitory cytokine 1 combined with prostate-specific antigen improves prostate cancer diagnosis. Clin Cancer Res 2006; 12: 89-96.