Inhibition of transient receptor potential channel 5 reverses 5-fluorouracil resistance in human colorectal cancer cells

Journal of Biological Chemistry

Volumn 290, Issue 1, 2015, Pages 448-456

  Wang, Teng ^a   Chen, Zhen ^a   Zhu, Yifei ^a   Pan, Qiongxi ^a   Liu, Yanjun ^a   Qi, Xiaowei ^a   Jin, Linfang ^a   Jin, Jian ^a   Ma, Xin ^a   Hua, Dong ^a  

^a JIANGNAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOTHERAPY; CYTOLOGY; DISEASES; DRUG THERAPY;

5-FLUOROURACIL (5-FU); ATP-BINDING CASSETTE; ATTRACTIVE STRATEGIES; CANCER PROGRESSION; COLORECTAL CANCER CELL; COLORECTAL CANCERS (CRC); SIGNAL PATHWAYS; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

CELLS;

BETA CATENIN; CYCLIN D1; FLUOROURACIL; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; SMALL INTERFERING RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL 5; VERAPAMIL; WNT PROTEIN; ABCB1 PROTEIN, HUMAN; ANTINEOPLASTIC AGENT; CTNNB1 PROTEIN, HUMAN; MULTIDRUG RESISTANCE PROTEIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL C; TRPC5 PROTEIN, HUMAN;

ABCB1 GENE; ARTICLE; CALCIUM MOBILIZATION; CANCER RESISTANCE; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; TRANSCRIPTION INITIATION; TRPC5 GENE; UPREGULATION; ANTAGONISTS AND INHIBITORS; COLON; DRUG EFFECTS; DRUG RESISTANCE; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; TUMOR CELL LINE; WNT SIGNALING PATHWAY;

ANTINEOPLASTIC AGENTS; BETA CATENIN; CELL LINE, TUMOR; COLON; DRUG RESISTANCE, NEOPLASM; EPITHELIAL CELLS; FLUOROURACIL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; P-GLYCOPROTEINS; RNA, SMALL INTERFERING; TRPC CATION CHANNELS; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84920661387     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.590364     Document Type: Article

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