P58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity

Biochemical Journal

Volumn 465, Issue , 2015, Pages 213-225

  Roobol, Anne ^a   Roobol, Jo ^a   Bastide, Amandine ^b   Knight, John R P ^b   Willis, Anne E ^a   Smales, C Mark ^a  

^a UNIVERSITY OF KENT   (United Kingdom)

^b MRC TOXICOLOGY UNIT   (United Kingdom)

Author keywords

DnaJ3C p58IPK; Eukaryotic Translation initiation factor 2 (eIF2 ) kinases; Eukaryotic translation initiation factor 2 kinase 4 (GCN2); MRNA; Protein synthesis; Translation

Indexed keywords

HEAT SHOCK PROTEIN 40; INITIATION FACTOR 2ALPHA; MESSENGER RNA; DNAJC3 PROTEIN, HUMAN; DNAJC3 PROTEIN, MOUSE; EIF2AK3 PROTEIN, HUMAN; EIF2AK4 PROTEIN, HUMAN; EIF2AK4 PROTEIN, MOUSE; INITIATION FACTOR 2; PERK KINASE; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRESS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FEMALE; MAMMAL CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN SYNTHESIS; RNA TRANSLATION; STRESS; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CYTOPLASM; GENE EXPRESSION REGULATION; GENETICS; HELA CELL LINE; HUMAN; KNOCKOUT MOUSE; METABOLISM; MOUSE; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN TRANSPORT;

EUKARYOTA; MAMMALIA;

ANIMALS; CYTOPLASM; EIF-2 KINASE; ENDOPLASMIC RETICULUM; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION REGULATION; HELA CELLS; HSP40 HEAT-SHOCK PROTEINS; HUMANS; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER;

EID: 84920614410     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20140852     Document Type: Article

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