MicroRNA profiling of the bovine alveolar macrophage response to Mycobacterium bovis infection suggests pathogen survival is enhanced by microRNA regulation of endocytosis and lysosome trafficking

Tuberculosis

Volumn 95, Issue 1, 2015, Pages 60-67

  Vegh, Peter ^a,b   Magee, David A ^c   Nalpas, Nicolas C ^c   Bryan, Kenneth ^a   McCabe, Matthew S ^a   Browne, John A ^c   Conlon, Kevin M ^c   Gordon, Stephen V ^c   Bradley, Daniel G ^b   Machugh, David E ^c   Lynn, David J ^a  

^a ANIMAL AND GRASSLAND RESEARCH AND INNOVATION CENTRE   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Alveolar macrophage microRNA; Bos Taurus; Mycobacterium bovis; RNA seq; Tuberculosis

Indexed keywords

BTA MICRORNA 142 5P; BTA MICRORNA 146A; BTA MICRORNA 423 3P; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; MICRORNA; RNA; SMALL UNTRANSLATED RNA; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UNCLASSIFIED DRUG; BACTERIAL RNA; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; TRANSFORMING GROWTH FACTOR BETA2;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL SURVIVAL; BOVINAE; BOVINE TUBERCULOSIS; CELL MIGRATION; CONTROLLED STUDY; ENDOCYTOSIS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE OVEREXPRESSION; INNATE IMMUNITY; LUNG ALVEOLUS MACROPHAGE; LYSOSOME; MACROPHAGE; MYCOBACTERIUM; MYCOBACTERIUM BOVIS; NEXT GENERATION SEQUENCING; NONHUMAN; PATHOGENESIS; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BOVINE; CELL CULTURE; DOWN REGULATION; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; LUNG TUBERCULOSIS; MALE; PHYSIOLOGY; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; UPREGULATION;

ANIMALS; CATTLE; CELLS, CULTURED; DOWN-REGULATION; ENDOCYTOSIS; GENE EXPRESSION; GENE EXPRESSION PROFILING; IMMUNITY, INNATE; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; LYSOSOMES; MACROPHAGES, ALVEOLAR; MALE; MICRORNAS; MYCOBACTERIUM BOVIS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, BACTERIAL; SEQUENCE ANALYSIS, RNA; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA2; TUBERCULOSIS, BOVINE; TUBERCULOSIS, PULMONARY; UP-REGULATION;

EID: 84920585028     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2014.10.011     Document Type: Article

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