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Volumn 16, Issue 6, 2014, Pages 722-735

Vpr overcomes macrophage-specific restriction of HIV-1 Env expression and virion production

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; LENTIVIRUS VECTOR; RALTEGRAVIR; UBIQUITIN PROTEIN LIGASE; VIRUS ENVELOPE PROTEIN; VPR PROTEIN; CARRIER PROTEIN; VPR PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; VPRBP PROTEIN, HUMAN;

EID: 84920573367     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2014.10.014     Document Type: Article
Times cited : (58)

References (47)
  • 1
    • 78549238925 scopus 로고    scopus 로고
    • HIV-1 Vpr loads uracil DNA glycosylase-2 onto DCAF1, a substrate recognition subunit of a cullin 4A-ring E3 ubiquitin ligase for proteasome-dependent degradation
    • J. Ahn, T. Vu, Z. Novince, J. Guerrero-Santoro, V. Rapic-Otrin, and A.M. Gronenborn HIV-1 Vpr loads uracil DNA glycosylase-2 onto DCAF1, a substrate recognition subunit of a cullin 4A-ring E3 ubiquitin ligase for proteasome-dependent degradation J. Biol. Chem. 285 2010 37333 37341
    • (2010) J. Biol. Chem. , vol.285 , pp. 37333-37341
    • Ahn, J.1    Vu, T.2    Novince, Z.3    Guerrero-Santoro, J.4    Rapic-Otrin, V.5    Gronenborn, A.M.6
  • 2
    • 77950646448 scopus 로고    scopus 로고
    • Limelight on two HIV/SIV accessory proteins in macrophage infection: Is Vpx overshadowing Vpr?
    • D. Ayinde, C. Maudet, C. Transy, and F. Margottin-Goguet Limelight on two HIV/SIV accessory proteins in macrophage infection: is Vpx overshadowing Vpr? Retrovirology 7 2010 35
    • (2010) Retrovirology , vol.7 , pp. 35
    • Ayinde, D.1    Maudet, C.2    Transy, C.3    Margottin-Goguet, F.4
  • 3
    • 0028297360 scopus 로고
    • Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: Mutational analysis of a primary HIV-1 isolate
    • J.W. Balliet, D.L. Kolson, G. Eiger, F.M. Kim, K.A. McGann, A. Srinivasan, and R. Collman Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: mutational analysis of a primary HIV-1 isolate Virology 200 1994 623 631
    • (1994) Virology , vol.200 , pp. 623-631
    • Balliet, J.W.1    Kolson, D.L.2    Eiger, G.3    Kim, F.M.4    McGann, K.A.5    Srinivasan, A.6    Collman, R.7
  • 6
    • 77950531446 scopus 로고    scopus 로고
    • HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs
    • C.C. Carter, A. Onafuwa-Nuga, L.A. McNamara, J. Riddell 4th, D. Bixby, M.R. Savona, and K.L. Collins HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs Nat. Med. 16 2010 446 451
    • (2010) Nat. Med. , vol.16 , pp. 446-451
    • Carter, C.C.1    Onafuwa-Nuga, A.2    McNamara, L.A.3    Riddell, J.4    Bixby, D.5    Savona, M.R.6    Collins, K.L.7
  • 7
    • 3142651460 scopus 로고    scopus 로고
    • Vpr-mediated incorporation of UNG2 into HIV-1 particles is required to modulate the virus mutation rate and for replication in macrophages
    • R. Chen, E. Le Rouzic, J.A. Kearney, L.M. Mansky, and S. Benichou Vpr-mediated incorporation of UNG2 into HIV-1 particles is required to modulate the virus mutation rate and for replication in macrophages J. Biol. Chem. 279 2004 28419 28425
    • (2004) J. Biol. Chem. , vol.279 , pp. 28419-28425
    • Chen, R.1    Le Rouzic, E.2    Kearney, J.A.3    Mansky, L.M.4    Benichou, S.5
  • 9
    • 84893810605 scopus 로고    scopus 로고
    • HIV-1 accessory proteins adapt cellular adaptors to facilitate immune evasion
    • D.R. Collins, and K.L. Collins HIV-1 accessory proteins adapt cellular adaptors to facilitate immune evasion PLoS Pathog. 10 2014 e1003851
    • (2014) PLoS Pathog. , vol.10 , pp. 1003851
    • Collins, D.R.1    Collins, K.L.2
  • 10
    • 0026442236 scopus 로고
    • An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1
    • R. Collman, J.W. Balliet, S.A. Gregory, H. Friedman, D.L. Kolson, N. Nathanson, and A. Srinivasan An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1 J. Virol. 66 1992 7517 7521
    • (1992) J. Virol. , vol.66 , pp. 7517-7521
    • Collman, R.1    Balliet, J.W.2    Gregory, S.A.3    Friedman, H.4    Kolson, D.L.5    Nathanson, N.6    Srinivasan, A.7
  • 11
    • 0028842207 scopus 로고
    • Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes
    • R.I. Connor, B.K. Chen, S. Choe, and N.R. Landau Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes Virology 206 1995 935 944
    • (1995) Virology , vol.206 , pp. 935-944
    • Connor, R.I.1    Chen, B.K.2    Choe, S.3    Landau, N.R.4
  • 13
    • 0035914839 scopus 로고    scopus 로고
    • HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells
    • D.A. Eckstein, M.P. Sherman, M.L. Penn, P.S. Chin, C.M. De Noronha, W.C. Greene, and M.A. Goldsmith HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells J. Exp. Med. 194 2001 1407 1419
    • (2001) J. Exp. Med. , vol.194 , pp. 1407-1419
    • Eckstein, D.A.1    Sherman, M.P.2    Penn, M.L.3    Chin, P.S.4    De Noronha, C.M.5    Greene, W.C.6    Goldsmith, M.A.7
  • 14
    • 0010472999 scopus 로고
    • Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone
    • T.M. Folks, K.A. Clouse, J. Justement, A. Rabson, E. Duh, J.H. Kehrl, and A.S. Fauci Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone Proc. Natl. Acad. Sci. USA 86 1989 2365 2368
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 2365-2368
    • Folks, T.M.1    Clouse, K.A.2    Justement, J.3    Rabson, A.4    Duh, E.5    Kehrl, J.H.6    Fauci, A.S.7
  • 15
    • 0028788472 scopus 로고
    • The role of human immunodeficiency virus type 1 envelope glycoproteins in virus infection
    • E.O. Freed, and M.A. Martin The role of human immunodeficiency virus type 1 envelope glycoproteins in virus infection J. Biol. Chem. 270 1995 23883 23886
    • (1995) J. Biol. Chem. , vol.270 , pp. 23883-23886
    • Freed, E.O.1    Martin, M.A.2
  • 19
    • 1642540589 scopus 로고    scopus 로고
    • HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse
    • C. Jolly, K. Kashefi, M. Hollinshead, and Q.J. Sattentau HIV-1 cell to cell transfer across an Env-induced, actin-dependent synapse J. Exp. Med. 199 2004 283 293
    • (2004) J. Exp. Med. , vol.199 , pp. 283-293
    • Jolly, C.1    Kashefi, K.2    Hollinshead, M.3    Sattentau, Q.J.4
  • 20
    • 67651092299 scopus 로고    scopus 로고
    • A cellular restriction dictates the permissivity of nondividing monocytes/macrophages to lentivirus and gammaretrovirus infection
    • R. Kaushik, X. Zhu, R. Stranska, Y. Wu, and M. Stevenson A cellular restriction dictates the permissivity of nondividing monocytes/macrophages to lentivirus and gammaretrovirus infection Cell Host Microbe 6 2009 68 80
    • (2009) Cell Host Microbe , vol.6 , pp. 68-80
    • Kaushik, R.1    Zhu, X.2    Stranska, R.3    Wu, Y.4    Stevenson, M.5
  • 24
    • 0033578072 scopus 로고    scopus 로고
    • Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner
    • J. Lama, A. Mangasarian, and D. Trono Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner Curr. Biol. 9 1999 622 631
    • (1999) Curr. Biol. , vol.9 , pp. 622-631
    • Lama, J.1    Mangasarian, A.2    Trono, D.3
  • 26
    • 18144379557 scopus 로고    scopus 로고
    • The Vpr protein from HIV-1: Distinct roles along the viral life cycle
    • E. Le Rouzic, and S. Benichou The Vpr protein from HIV-1: distinct roles along the viral life cycle Retrovirology 2 2005 11
    • (2005) Retrovirology , vol.2 , pp. 11
    • Le Rouzic, E.1    Benichou, S.2
  • 28
    • 0028800265 scopus 로고
    • A leucine triplet repeat sequence (LXX)4 in p6gag is important for Vpr incorporation into human immunodeficiency virus type 1 particles
    • Y.L. Lu, R.P. Bennett, J.W. Wills, R. Gorelick, and L. Ratner A leucine triplet repeat sequence (LXX)4 in p6gag is important for Vpr incorporation into human immunodeficiency virus type 1 particles J. Virol. 69 1995 6873 6879
    • (1995) J. Virol. , vol.69 , pp. 6873-6879
    • Lu, Y.L.1    Bennett, R.P.2    Wills, J.W.3    Gorelick, R.4    Ratner, L.5
  • 29
    • 44649139364 scopus 로고    scopus 로고
    • HIV-1 accessory proteins - Ensuring viral survival in a hostile environment
    • M.H. Malim, and M. Emerman HIV-1 accessory proteins - ensuring viral survival in a hostile environment Cell Host Microbe 3 2008 388 398
    • (2008) Cell Host Microbe , vol.3 , pp. 388-398
    • Malim, M.H.1    Emerman, M.2
  • 30
    • 51349123523 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development
    • C.M. McCall, P.L. Miliani de Marval, P.D. Chastain 2nd, S.C. Jackson, Y.J. He, Y. Kotake, J.G. Cook, and Y. Xiong Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development Mol. Cell. Biol. 28 2008 5621 5633
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 5621-5633
    • McCall, C.M.1    Miliani De Marval, P.L.2    Chastain, P.D.3    Jackson, S.C.4    He, Y.J.5    Kotake, Y.6    Cook, J.G.7    Xiong, Y.8
  • 31
    • 33644762969 scopus 로고    scopus 로고
    • Inhibition of receptor binding stabilizes Newcastle disease virus HN and F protein-containing complexes
    • L.W. McGinnes, and T.G. Morrison Inhibition of receptor binding stabilizes Newcastle disease virus HN and F protein-containing complexes J. Virol. 80 2006 2894 2903
    • (2006) J. Virol. , vol.80 , pp. 2894-2903
    • McGinnes, L.W.1    Morrison, T.G.2
  • 32
    • 84877954030 scopus 로고    scopus 로고
    • CD133+ HPCs harbor HIV genomes in a subset of optimally treated people with long-term viral suppression
    • L.A. McNamara, A. Onafuwa-Nuga, N.T. Sebastian, J. Riddell 4th, D. Bixby, and K.L. Collins CD133+ HPCs harbor HIV genomes in a subset of optimally treated people with long-term viral suppression J. Infect. Dis. 207 2013 1807 1816
    • (2013) J. Infect. Dis. , vol.207 , pp. 1807-1816
    • McNamara, L.A.1    Onafuwa-Nuga, A.2    Sebastian, N.T.3    Riddell, J.4    Bixby, D.5    Collins, K.L.6
  • 34
    • 0032951899 scopus 로고    scopus 로고
    • Binding of human immunodeficiency virus type 1 Gag to membrane: Role of the matrix amino terminus
    • A. Ono, and E.O. Freed Binding of human immunodeficiency virus type 1 Gag to membrane: role of the matrix amino terminus J. Virol. 73 1999 4136 4144
    • (1999) J. Virol. , vol.73 , pp. 4136-4144
    • Ono, A.1    Freed, E.O.2
  • 35
    • 3042816008 scopus 로고    scopus 로고
    • Overview of primate lentiviruses and their evolution in non-human primates in Africa
    • M. Peeters, and V. Courgnaud Overview of primate lentiviruses and their evolution in non-human primates in Africa HIV Sequence Compendium 2002 2 23
    • (2002) HIV Sequence Compendium , pp. 2-23
    • Peeters, M.1    Courgnaud, V.2
  • 36
    • 79959353247 scopus 로고    scopus 로고
    • Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon
    • T. Pertel, C. Reinhard, and J. Luban Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon Retrovirology 8 2011 49
    • (2011) Retrovirology , vol.8 , pp. 49
    • Pertel, T.1    Reinhard, C.2    Luban, J.3
  • 37
    • 0037444303 scopus 로고    scopus 로고
    • Differential incorporation of uracil DNA glycosylase UNG2 into HIV-1, HIV-2, and SIV(MAC) viral particles
    • S. Priet, J.M. Navarro, N. Gros, G. Quérat, and J. Sire Differential incorporation of uracil DNA glycosylase UNG2 into HIV-1, HIV-2, and SIV(MAC) viral particles Virology 307 2003 283 289
    • (2003) Virology , vol.307 , pp. 283-289
    • Priet, S.1    Navarro, J.M.2    Gros, N.3    Quérat, G.4    Sire, J.5
  • 39
    • 0033578016 scopus 로고    scopus 로고
    • Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein
    • T.M. Ross, A.E. Oran, and B.R. Cullen Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein Curr. Biol. 9 1999 613 621
    • (1999) Curr. Biol. , vol.9 , pp. 613-621
    • Ross, T.M.1    Oran, A.E.2    Cullen, B.R.3
  • 40
    • 44249091181 scopus 로고    scopus 로고
    • Production and titration of lentiviral vectors
    • CHAPTER Unit 12, 10
    • P. Salmon, and D. Trono Production and titration of lentiviral vectors Curr. Protoc. Hum. Genet. Chapter 12 2007 Unit 12, 10
    • (2007) Curr. Protoc. Hum. Genet. , vol.12
    • Salmon, P.1    Trono, D.2
  • 41
    • 0021952907 scopus 로고
    • Genes regulating HLA class i antigen expression in T-B lymphoblast hybrids
    • R.D. Salter, D.N. Howell, and P. Cresswell Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids Immunogenetics 21 1985 235 246
    • (1985) Immunogenetics , vol.21 , pp. 235-246
    • Salter, R.D.1    Howell, D.N.2    Cresswell, P.3
  • 45
    • 0030062864 scopus 로고    scopus 로고
    • Construction and characterization of a stable full-length macrophage-tropic HIV type 1 molecular clone that directs the production of high titers of progeny virions
    • T.S. Theodore, G. Englund, A. Buckler-White, C.E. Buckler, M.A. Martin, and K.W. Peden Construction and characterization of a stable full-length macrophage-tropic HIV type 1 molecular clone that directs the production of high titers of progeny virions AIDS Res. Hum. Retroviruses 12 1996 191 194
    • (1996) AIDS Res. Hum. Retroviruses , vol.12 , pp. 191-194
    • Theodore, T.S.1    Englund, G.2    Buckler-White, A.3    Buckler, C.E.4    Martin, M.A.5    Peden, K.W.6
  • 46
    • 34848911347 scopus 로고    scopus 로고
    • The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor
    • X. Wen, K.M. Duus, T.D. Friedrich, and C.M. de Noronha The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor J. Biol. Chem. 282 2007 27046 27057
    • (2007) J. Biol. Chem. , vol.282 , pp. 27046-27057
    • Wen, X.1    Duus, K.M.2    Friedrich, T.D.3    De Noronha, C.M.4
  • 47
    • 84856159248 scopus 로고    scopus 로고
    • The HIV1 protein Vpr acts to enhance constitutive DCAF1-dependent UNG2 turnover
    • X. Wen, L. Casey Klockow, M. Nekorchuk, H.J. Sharifi, and C.M. de Noronha The HIV1 protein Vpr acts to enhance constitutive DCAF1-dependent UNG2 turnover PLoS ONE 7 2012 e30939
    • (2012) PLoS ONE , vol.7 , pp. 30939
    • Wen, X.1    Casey Klockow, L.2    Nekorchuk, M.3    Sharifi, H.J.4    De Noronha, C.M.5


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