Differential incorporation of uracil DNA glycosylase UNG2 into HIV-1, HIV-2, and SIVMAC viral particles

Virology

Volumn 307, Issue 2, 2003, Pages 283-289

  Priet, S téphane ^a   Navarro, Jean Marc ^a   Gros, Nathalie ^a   Quérat, Gilles ^a   Sire, Joséphine ^a  

^a INSERM   (France)

Author keywords

HIV 1; HIV 1 SIV IN chimeric viruses; HIV 2; Integrase; SIV; Uracil DNA glycosylase UNG2

Indexed keywords

URACIL DNA GLYCOSYLTRANSFERASE;

ARTICLE; CHIMERA; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; NONHUMAN; PHYLOGENY; PRECIPITATION; PRIORITY JOURNAL; PROTEIN INTERACTION; PURIFICATION; SIMIAN IMMUNODEFICIENCY VIRUS; STRAIN DIFFERENCE; VIRUS MUTANT; VIRUS PARTICLE; WESTERN BLOTTING;

HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; PRIMATES; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 0037444303     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0042-6822(02)00073-9     Document Type: Article

References (24)

1. Bouhamdan M., Benichou S., Rey F., Navarro J.M., Agostini I., Spire B., Camonis J., Slupphaug G., Vigne R., Benarous R., Sire J. Human immunodeficiency virus type 1 Vpr protein binds to the uracil DNA glycosylase DNA repair enzyme. J. Virol. 70:1996;697-704.
2. Courcelle C.T., Courcelle J., Prichard M.N., Mocarski E.S. Requirement for uracil-DNA glycosylase during the transition to late-phase cytomegalovirus DNA replication. J. Virol. 75:2001;7592-7601.
3. Elder J.H., Lerner D.L., Hasselkus-Light C.S., Fontenot D.J., Hunter E., Luciw P.A., Montelaro R.C., Phillips T.R. Distinct subsets of retroviruses encode dUTPase. J. Virol. 66:1992;1791-1794.
4. Ellison K.S., Peng W., McFadden G. Mutations in active-site residues of the uracil-DNA glycosylase encoded by vaccinia virus are incompatible with virus viability. J. Virol. 70:1996;7965-7973.
5. Focher F., Verri A., Verzeletti S., Mazzarello P., Spadari S. Uracil in OriS of herpes simplex 1 alters its specific recognition by origin binding protein (OBP) does virus induced uracil-DNA glycosylase play a key role in viral reactivation and replication? Chromosoma. 102:1992;S67-71.
6. Haushalter K.A., Todd Stukenberg M.W., Kirschner M.W., Verdine G.L. Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors. Curr. Biol. 9:1999;174-185.
7. Hendrich B., Hardeland U., Ng H.H., Jiricny J., Bird A. The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites. Nature. 401:1999;301-304.
8. Jacotot E., Ravagnan L., Loeffler M., Ferri K.F., Vieira H.L., Zamzami N., Costantini P., Druillennec S., Hoebeke J., Briand J.P., Irinopoulou T., Daugas E., Susin S.A., Cointe D., Xie Z.H., Reed J.C., Roques B.P., Kroemer G. The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore. J. Exp. Med. 191:2000;33-46.
9. Krokan H.E., Standal R., Slupphaug G. DNA glycosylases in the base excision repair of DNA. Biochem. J. 325:1997;1-16.
10. Lindahl T. Instability and decay of the primary structure of DNA. Nature. 362:1993;709-715.
11. Liu H., Wu X., Xiao H., Kappes J.C. Targeting human immunodeficiency virus (HIV) type 2 integrase protein into HIV type 1. J. Virol. 73:1999;8831-8836.
12. Mansky L.M., Preveral S., Selig L., Benarous R., Benichou S. The interaction of vpr with uracil DNA glycosylase modulates the human immunodeficiency virus type 1 in vivo mutation rate. J. Virol. 74:2000;7039-7047.
13. Muller S.J., Caradonna S. Cell cycle regulation of a human cyclin-like gene encoding uracil-DNA glycosylase. J. Biol. Chem. 268:1993;1310-1319.
14. Neddermann P., Jiricny J. Efficient removal of uracil from G.U mispairs by the mismatch-specific thymine DNA glycosylase from HeLa cells. Proc. Natl. Acad. Sci. USA. 91:1994;1642-1646.
15. Nilsen H., Otterlei M., Haug T., Solum K., Nagelhus T.A., Skorpen F., Krokan H.E. Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene. Nucleic Acids Res. 25:1997;750-755.
16. Otterlei M., Haug T., Nagelhus T.A., Slupphaug G., Lindmo T., Krokan H.E. Nuclear and mitochondrial splice forms of human uracil-DNA glycosylase contain a complex nuclear localisation signal and a strong classical mitochondrial localisation signal, respectively. Nucleic Acids Res. 26:1998;4611-4617.
17. Prichard M.N., Duke G.M., Mocarski E.S. Human cytomegalovirus uracil DNA glycosylase is required for the normal temporal regulation of both DNA synthesis and viral replication. J. Virol. 70:1996;3018-3025.
18. Pyles R.B., Thompson R.L. Mutations in accessory DNA replicating functions alter the relative mutation frequency of herpes simplex virus type 1 strains in cultured murine cells. J. Virol. 68:1994;4514-4524.
19. Selig L., Benichou S., Rogel M.E., Wu L.I., Vodicka M.A., Sire J., Benarous R., Emerman M. Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrest. J. Virol. 71:1997;4842-4846.
20. Sleigh R., Sharkey M., Newman M.A., Hahn B., Stevenson M. Differential association of uracil DNA glycosylase with SIVSM Vpr and Vpx proteins. Virology. 245:1998;338-343.
21. Steagall W.K., Robek M.D., Perry S.T., Fuller F.J., Payne S.L. Incorporation of uracil into viral DNA correlates with reduced replication of EIAV in macrophages. Virology. 210:1995;302-313.
22. Turelli P., Guiguen F., Mornex J.F., Vigne R., Querat G. dUTPase-minus caprine arthritis-encephalitis virus is attenuated for pathogenesis and accumulates G-to-A substitutions. J. Virol. 71:1997;4522-4530.
23. Verri A., Mazzarello P., Biamonti G., Spadari S., Focher F. The specific binding of nuclear protein(s) to the cAMP responsive element (CRE) sequence (TGACGTCA) is reduced by the misincorporation of U and increased by the deamination of C. Nucleic Acids Res. 18:1990;5775-5780.
24. Willetts K.E., Rey F., Agostini I., Navarro J.M., Baudat Y., Vigne R., Sire J. DNA repair enzyme uracil DNA glycosylase is specifically incorporated into human immunodeficiency virus type 1 viral particles through a Vpr-independent mechanism. J. Virol. 73:1999;1682-1688.