Fat quality and incident cardiovascular disease, allcause mortality, and cancer mortality

Journal of Clinical Endocrinology and Metabolism

Volumn 100, Issue 1, 2015, Pages 227-234

  Rosenquist, Klara J ^a,b,c   Massaro, Joseph M ^d   Pedley, Alison ^b,c   Long, Michelle T ^b,c,e   Kreger, Bernard E ^b,f   Vasan, Ramachandran S ^b,g,h   Murabito, Joanne M ^b,f   Hoffmann, Udo ^g,h   Fox, Caroline S ^a,b,c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b FRAMINGHAM HEART STUDY   (United States)

^c Center for Population Studies   (United States)

^d BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^e Section of Gastroenterology   (United States)

^f Section of General Internal Medicine   (United States)

^g BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BODY MASS; CANCER INCIDENCE; CANCER MORTALITY; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; COHORT ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; DISEASE ASSOCIATION; FAT MASS; FEMALE; FOLLOW UP; HUMAN; INTRAABDOMINAL FAT; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; OBESITY; OUTCOME ASSESSMENT; RISK ASSESSMENT; SUBCUTANEOUS FAT; CARDIOVASCULAR DISEASES; INCIDENCE; MIDDLE AGED; MORTALITY; NEOPLASMS; PROSPECTIVE STUDY; RADIOGRAPHY; RISK FACTOR;

ADULT; CARDIOVASCULAR DISEASES; COHORT STUDIES; FEMALE; HUMANS; INCIDENCE; INTRA-ABDOMINAL FAT; MALE; MIDDLE AGED; NEOPLASMS; OBESITY; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 84920568608     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2013-4296     Document Type: Article

References (40)

1. Flegal KM,Carroll MD,Ogden CL,Curtin LR. Prevalence and trends in obesity among US adults, 1999-2008 JAMA. 2010 303 3 235-241.
2. Fox CS, Massaro JM, Hoffmann U, et al. Abdominal visceral and subcutaneous adipose tissue compartments: ass ociation with metabolic risk factors in the Framingham Heart Study. Circulation. 2007;116:39-48.
3. Goodpaster BH, Krishnaswami S, Harris TB, et al. Obesity, regional body fat distribution, and the metabolic syndrome in older men and women. Arch Intern Med. 2005;165(7):777-783.
4. McLaughlin T, Abbasi F, Lamendola C, Reaven G. Heterogeneity in the prevalence of risk factors for cardiovascular disease and type 2 diabetes mellitus in obese individuals: effect of differences in insulin sensitivity. Arch Intern Med. 2007;167(7):642-648.
5. Calle EE, Thun MJ, Petrelli JM, Rodriguez C, Heath CW. Bodymass index and mortality in a prospective cohort of U.S. adults. N Engl J Med. 1999;341(15):1097-1105.
6. Prospective Studies Collaboration, Whitlock G, Lewington S, Sherliker P, et al. Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 pr ospective studies. Lancet. 2009;373(9669):1083-1096.
7. Klö ting N, Fasshauer M, Dietrich A, et al. Insulin-sensitive obesity. Am J Physiol Endocrinol Metab. 2010;299(3):E506-E515.
8. McLaughlin T, Lamendola C, Liu A, Abbasi F. Preferential fat deposition in subcutaneous versus visceral depots is associated with insulin sensitivity. J Clin Endocrinol Metab. 2011;96(11 ):E1756-E1760.
9. Baba S, Jacene HA, Engles JM, Honda H, Wahl RL. CT Hounsfield units of brown adipose tissue increase with activation: preclinical and clinical studies. J Nuclear Med. 2010;51(2):246-250.
10. Hu HH, Chung SA, Nayak KS, Jackson HA, Gilsanz V. Differential computed tomographic attenuation of metabolically active and inactive adipose tissues: preliminary findings. J Comput Assist Tomogr. 2011;35:65-71.
11. Murphy RA, Register TC, Shively CA, et al. Adipose tissue density, a novel biomarker predicting mortality risk in older adults. J Gerontol A Biol Sci Med Sci. 2014;69(1):109-117.
12. Rosenquist KJ, Pedley A, Massaro JM, et al. Visceral and subcutaneous fat quality is associated with cardiometabolic risk. JACC Cardiovasc Imaging. 2013;6(7):762-771.
13. Lieb W, Safa R, Benjamin EJ, et al. Vascular endothelial growth factor, its soluble receptor, and hepatocyte growth factor: clinical and genetic correlates and association with vascular function. Eur Heart J. 2009;30(9):1121-1127.
14. Lieb W, Zachariah JP, Xanthakis V, et al. Clinical and genetic correlates of circulating angiopoietin-2 and soluble Tie-2 in the community. Circ Card iovasc Genet. 2010;3(3):300-306.
15. O'Seaghdha CM, Hwang SJ, Bhavsar NA, et al. Lower urinary connective tissue growth factor levels and incident CKD stage 3 in the general population. Am J Kid ney Dis. 2011;57(6):841-849.
16. Després JP, Moorjani S, Lupien PJ, Tremblay A, Nadeau A, Bouchard C. Regional distribution of body fat, plasma lipoproteins, and cardiovascular disease. Arteriosclerosis. 1990;10(4):497-511.
17. Nieves DJ, Cnop M, Retzlaff B, et al. The atherogenic lipoprotein profile associated with obesity and insulin resistance is largely attributable to intra-Abdominal fat. Diabetes. 2003;52(1):172-179.
18. Katzmarzyk PT, Mire E, Bouchard C. Abdominal obesity and mortality: The Pennington Center Longitudinal Study. Nutr Diabetes. 2012;2:e42.
19. Britton KA, Massaro JM, Murabito JM, Kreger BE, Hoffmann U, Fox CS. Body fat distribution, incident cardiovascular disease, cancer, and all-cause mortality. J Am Coll Cardiol. 2013;62(10):921-925.
20. Weyer C, Foley JE, Bogardus C, Tataranni PA, Pratley RE. Enlarged subcutaneous abdominal adipocyte size, but not obesity itself, predicts Type II diabetes independent of insulin resistance. Diabetologia. 2000;43(12):1 498-1506.
21. Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest. 2003;112:1796-180 8.
22. Apovian CM,Bigornia S,Mott M,et al. Adipose macrophage infiltration is associated with insulin resistance and vascular endothelial dysfunction in obese subjects Arterioscler Thromb Vasc Biol. 2008 28(9 1654-1659.
23. Bremer AA, Jialal I. Adipose tissue dysfunction in nascent metabolic syndrome. J Obes. 2013;2013:393192.
24. Shen W, Punyanitya M, Silva AM, et al. Sexual dimorphism of adipose tissue distribution across the lifespan: a cross-sectional whole-body magnetic resonance imaging study. Nutr Metab (Lond). 2009;6:17.
25. Spencer M, Unal R, Zhu B, et al. Adipose tissue extracellular matrix and vascular abnormalities in obesity and insulin resistance. J Clin Endocrinol Metab. 2011;96(12):E1990-E1998.
26. Divoux A, Tordjman J, Lacasa D, et al. Fibrosis in human adipose tissue: composition, distribution, and link with lipid metabolism and fat mass loss. Diabetes 2010; 59(11):2817-2825.
27. Pasarica M, Gowronska-Kozak B, Burk D, et al. Adipose tissue collagen VI in obesity. J Clin Endocrinol Metab. 2009;94(12):5155-5162.
28. Divoux A, Clément K. Architecture and the extracellular matrix: The still unappreciated components of the adipose tissue. Obes Rev. 2011;12(5):e494-e503.
29. Duncan MR, Berman B. Stimulation of collagen and glycosaminoglycan production in cultured human adult dermal fibroblasts by recombinant human in terleukin 6. J Invest Dermatol. 1991;97(4): 686-692.
30. Nieman KM, Romero IL, Van Houten B, Lengyel E. Adipose tissue and adipocytes support tumorigenesis and metastasis. Biochim Biophys Acta. 2013;1831(10):1533-1541.
31. Dirat B, Bochet L, Dabek M, et al. Cancer-Associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion. Cancer Res. 2011;71(7):2455-2465.
32. Furlan A, Fakhran S, Federle MP. Spontaneous abdominal hemorrhage: causes, CT findings, and clinical implications. AJR Am J Roentgenol. 2009;193(4):1077-1087.
33. Gealekman O, Guseva N, Hartigan C, et al. Depot-specific differences and insufficient subcutaneous adipose tissue angiogenesis in h uman obesity. Circulation. 2011;123(2):186-194.
34. Pasarica M, Sereda OR, Redman LM, et al. Reduced adipose tissue oxygenation in human obesity: evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response. Diabetes. 2009;58(3):718-725.
35. Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med. 1971;285(21):1182-1186.
36. Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med. 2003;348(17):1625-163 8.
37. Berrington de Gonzalez A, Hartge P, Cerhan JR, et al. Body-mass index and mortality among 1.46 million white adults.NEngl J Med. 2010;363(23):2211-2219.
38. Flegal KM, Graubard BI, Williamson DF, Gail MH. Cause-specific excess deaths associated with underweight, overweight, and obesity. JAMA. 2007;298(17):2028-2037.
39. Flegal KM, Kit BK, Orpana H, Graubard BI. Association of allcause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-Analysis. JAMA. 2013;309(1):71-82.
40. Orpana HM, B erthelot JM, Kaplan MS, Feeny DH, McFarland B, Ross NA. BMI and mortality: results from a national longitudinal study of Canadian adults. Obesity (Silver Spring). 2010;18(1):214-218.