메뉴 건너뛰기




Volumn 112, Issue 1, 2015, Pages E39-E48

γδ T cells affect IL-4 production and B-cell tolerance

Author keywords

Autoimmunity; Gammadelta t cell; Immunoglobulin; Interleukin 4; Tolerance

Indexed keywords

AUTOANTIBODY; CD22 ANTIGEN; CD32 ANTIGEN; CD5 ANTIGEN; IMMUNOGLOBULIN E ANTIBODY; INTERLEUKIN 4; ANTIBODY; IMMUNOGLOBULIN E; LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 84920548357     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1415107111     Document Type: Article
Times cited : (37)

References (52)
  • 1
    • 77954143558 scopus 로고    scopus 로고
    • Gammadelta T cell effector functions: A blend of innate programming and acquired plasticity
    • Bonneville M, O'Brien RL, Born WK (2010) Gammadelta T cell effector functions: A blend of innate programming and acquired plasticity. Nat Rev Immunol 10(7):467-478.
    • (2010) Nat Rev Immunol , vol.10 , Issue.7 , pp. 467-478
    • Bonneville, M.1    O'Brien, R.L.2    Born, W.K.3
  • 2
  • 3
    • 0021909349 scopus 로고
    • Structure, organization, and somatic rearrangement of T cell gamma genes
    • Hayday AC, et al. (1985) Structure, organization, and somatic rearrangement of T cell gamma genes. Cell 40(2):259-269.
    • (1985) Cell , vol.40 , Issue.2 , pp. 259-269
    • Hayday, A.C.1
  • 4
    • 0023605091 scopus 로고
    • T-cell receptor δ gene rearrangements in early thymocytes
    • Chien Y-H, et al. (1987) T-cell receptor δ gene rearrangements in early thymocytes. Nature 330(6150):722-727.
    • (1987) Nature , vol.330 , Issue.6150 , pp. 722-727
    • Chien, Y.-H.1
  • 5
    • 84902090448 scopus 로고    scopus 로고
    • Quantitative peripheral blood perturbations of γδ T cells in human disease and their clinical implications
    • Bank I, Marcu-Malina V (2014) Quantitative peripheral blood perturbations of γδ T cells in human disease and their clinical implications. Clin Rev Allergy Immunol 47(3):311-333.
    • (2014) Clin Rev Allergy Immunol , vol.47 , Issue.3 , pp. 311-333
    • Bank, I.1    Marcu-Malina, V.2
  • 6
    • 0025352593 scopus 로고
    • Evidence for extrathymic changes in the T cell receptor γ/δ repertoire
    • Parker CM, et al. (1990) Evidence for extrathymic changes in the T cell receptor γ/δ repertoire. J Exp Med 171(5):1597-1612.
    • (1990) J Exp Med , vol.171 , Issue.5 , pp. 1597-1612
    • Parker, C.M.1
  • 7
    • 0023690608 scopus 로고
    • Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors
    • Havran WL, Allison JP (1988) Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors. Nature 335(6189):443-445.
    • (1988) Nature , vol.335 , Issue.6189 , pp. 443-445
    • Havran, W.L.1    Allison, J.P.2
  • 9
    • 33846786954 scopus 로고    scopus 로고
    • gammadelta T-cell receptors: Functional correlations
    • O'Brien RL, et al. (2007) gammadelta T-cell receptors: Functional correlations. Immunol Rev 215:77-88.
    • (2007) Immunol Rev , vol.215 , pp. 77-88
    • O'Brien, R.L.1
  • 10
    • 70249116114 scopus 로고    scopus 로고
    • The influence of IgE-enhancing and IgE-suppressive gammadelta T cells changes with exposure to inhaled ovalbumin
    • Huang Y, et al. (2009) The influence of IgE-enhancing and IgE-suppressive gammadelta T cells changes with exposure to inhaled ovalbumin. J Immunol 183(2):849-855.
    • (2009) J Immunol , vol.183 , Issue.2 , pp. 849-855
    • Huang, Y.1
  • 11
    • 62849124659 scopus 로고    scopus 로고
    • CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsets
    • Ribot JC, et al. (2009) CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsets. Nat Immunol 10(4):427-436.
    • (2009) Nat Immunol , vol.10 , Issue.4 , pp. 427-436
    • Ribot, J.C.1
  • 13
    • 0026454619 scopus 로고
    • Peripheral T cell receptor γδ variable gene repertoire maps to the T cell receptor loci and is influenced by positive selection
    • Sperling AI, Cron RQ, Decker DC, Stern DA, Bluestone JA (1992) Peripheral T cell receptor γδ variable gene repertoire maps to the T cell receptor loci and is influenced by positive selection. J Immunol 149(10):3200-3207.
    • (1992) J Immunol , vol.149 , Issue.10 , pp. 3200-3207
    • Sperling, A.I.1    Cron, R.Q.2    Decker, D.C.3    Stern, D.A.4    Bluestone, J.A.5
  • 14
    • 10744227223 scopus 로고    scopus 로고
    • Different potentials of γδ T cell subsets in regulating airway responsiveness: V γ 1+ cells, but not V γ 4+ cells, promote airway hyperreactivity, Th2 cytokines, and airway inflammation
    • Hahn Y-S, et al. (2004) Different potentials of γδ T cell subsets in regulating airway responsiveness: V γ 1+ cells, but not V γ 4+ cells, promote airway hyperreactivity, Th2 cytokines, and airway inflammation. J Immunol 172(5):2894-2902.
    • (2004) J Immunol , vol.172 , Issue.5 , pp. 2894-2902
    • Hahn, Y.-S.1
  • 15
    • 81455141987 scopus 로고    scopus 로고
    • Regulatory role of Vγ1 γδ T cells in tumor immunity through IL-4 production
    • Hao J, et al. (2011) Regulatory role of Vγ1 γδ T cells in tumor immunity through IL-4 production. J Immunol 187(10):4979-4986.
    • (2011) J Immunol , vol.187 , Issue.10 , pp. 4979-4986
    • Hao, J.1
  • 16
    • 0031137016 scopus 로고    scopus 로고
    • Developmentally ordered V-J recombination in mouse T cell receptor γ locus is not perturbed by targeted deletion of the Vgamma4 gene
    • Sunaga S, Maki K, Komagata Y, Miyazaki J, Ikuta K (1997) Developmentally ordered V-J recombination in mouse T cell receptor γ locus is not perturbed by targeted deletion of the Vgamma4 gene. J Immunol 158(9):4223-4228.
    • (1997) J Immunol , vol.158 , Issue.9 , pp. 4223-4228
    • Sunaga, S.1    Maki, K.2    Komagata, Y.3    Miyazaki, J.4    Ikuta, K.5
  • 17
    • 22544466384 scopus 로고    scopus 로고
    • Delineation of the function of a major gamma delta T cell subset during infection
    • Andrew EM, et al. (2005) Delineation of the function of a major gamma delta T cell subset during infection. J Immunol 175(3):1741-1750.
    • (2005) J Immunol , vol.175 , Issue.3 , pp. 1741-1750
    • Andrew, E.M.1
  • 18
    • 0027474344 scopus 로고
    • T cell receptor delta gene mutant mice: Independent generation of alpha beta T cells and programmed rearrangements of gamma delta TCR genes
    • Itohara S, et al. (1993) T cell receptor delta gene mutant mice: Independent generation of alpha beta T cells and programmed rearrangements of gamma delta TCR genes. Cell 72(3):337-348.
    • (1993) Cell , vol.72 , Issue.3 , pp. 337-348
    • Itohara, S.1
  • 19
    • 0042333400 scopus 로고    scopus 로고
    • V γ 4+ γ delta T cells regulate airway hyperreactivity to methacholine in ovalbumin-sensitized and challenged mice
    • Hahn Y-S, et al. (2003) V γ 4+ γ delta T cells regulate airway hyperreactivity to methacholine in ovalbumin-sensitized and challenged mice. J Immunol 171(6):3170-3178.
    • (2003) J Immunol , vol.171 , Issue.6 , pp. 3170-3178
    • Hahn, Y.-S.1
  • 20
    • 0025921585 scopus 로고
    • Alpha beta T-lymphocyte depleted mice, a model for γδ T-lymphocyte functional studies
    • Carbone A, et al. (1991) Alpha beta T-lymphocyte depleted mice, a model for γδ T-lymphocyte functional studies. Immunol Rev 120:35-50.
    • (1991) Immunol Rev , vol.120 , pp. 35-50
    • Carbone, A.1
  • 21
    • 70449578104 scopus 로고    scopus 로고
    • Polyclonal IgE induces mast cell survival and cytokine production
    • Kashiwakura J, et al. (2009) Polyclonal IgE induces mast cell survival and cytokine production. Allergol Int 58(3):411-419.
    • (2009) Allergol Int , vol.58 , Issue.3 , pp. 411-419
    • Kashiwakura, J.1
  • 22
    • 0034948713 scopus 로고    scopus 로고
    • Regulation of mast cell survival by IgE
    • Asai K, et al. (2001) Regulation of mast cell survival by IgE. Immunity 14(6):791-800.
    • (2001) Immunity , vol.14 , Issue.6 , pp. 791-800
    • Asai, K.1
  • 23
    • 84870393179 scopus 로고    scopus 로고
    • An update on the hyper-IgE syndromes
    • Yong PF, et al. (2012) An update on the hyper-IgE syndromes. Arthritis Res Ther 14(6):228-237.
    • (2012) Arthritis Res Ther , vol.14 , Issue.6 , pp. 228-237
    • Yong, P.F.1
  • 24
    • 77957729025 scopus 로고    scopus 로고
    • Somatic hypermutation as a generator of antinuclear antibodies in a murine model of systemic autoimmunity
    • Guo W, et al. (2010) Somatic hypermutation as a generator of antinuclear antibodies in a murine model of systemic autoimmunity. J Exp Med 207(10):2225-2237.
    • (2010) J Exp Med , vol.207 , Issue.10 , pp. 2225-2237
    • Guo, W.1
  • 25
    • 84872719419 scopus 로고    scopus 로고
    • Antigen-specific regulation of IgE antibodies by non-antigen-specific γδ T cells
    • Huang Y, et al. (2013) Antigen-specific regulation of IgE antibodies by non-antigen-specific γδ T cells. J Immunol 190(3):913-921.
    • (2013) J Immunol , vol.190 , Issue.3 , pp. 913-921
    • Huang, Y.1
  • 26
    • 0033567957 scopus 로고    scopus 로고
    • IL-4-producing γδ T cells that express a very restricted TCR repertoire are preferentially localized in liver and spleen
    • Gerber DJ, et al. (1999) IL-4-producing γδ T cells that express a very restricted TCR repertoire are preferentially localized in liver and spleen. J Immunol 163(6):3076-3082.
    • (1999) J Immunol , vol.163 , Issue.6 , pp. 3076-3082
    • Gerber, D.J.1
  • 27
    • 0023679974 scopus 로고
    • IL-4 is required to generate and sustain in vivo IgE responses
    • Finkelman FD, et al. (1988) IL-4 is required to generate and sustain in vivo IgE responses. J Immunol 141(7):2335-2341.
    • (1988) J Immunol , vol.141 , Issue.7 , pp. 2335-2341
    • Finkelman, F.D.1
  • 28
    • 66249138887 scopus 로고    scopus 로고
    • Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo
    • Berg LJ
    • Felices M, Yin CC, Kosaka Y, Kang J, Berg LJ (2009) Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo. Proc Natl Acad Sci USA 106(20):8308-8313.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.20 , pp. 8308-8313
    • Felices, M.1    Yin, C.C.2    Kosaka, Y.3    Kang, J.4
  • 29
    • 70149110081 scopus 로고    scopus 로고
    • Enhanced development of CD4+ gammadelta T cells in the absence of Itk results in elevated IgE production
    • Qi Q, et al. (2009) Enhanced development of CD4+ gammadelta T cells in the absence of Itk results in elevated IgE production. Blood 114(3):564-571.
    • (2009) Blood , vol.114 , Issue.3 , pp. 564-571
    • Qi, Q.1
  • 30
    • 0023069479 scopus 로고
    • B-cell stimulatory factor-1/interleukin 4
    • Paul WE, Ohara J (1987) B-cell stimulatory factor-1/interleukin 4. Annu Rev Immunol 5:429-459.
    • (1987) Annu Rev Immunol , vol.5 , pp. 429-459
    • Paul, W.E.1    Ohara, J.2
  • 31
    • 0037406914 scopus 로고    scopus 로고
    • Differential contribution of IL-4 and STAT6 vs STAT4 to the development of lupus nephritis
    • Singh RR, et al. (2003) Differential contribution of IL-4 and STAT6 vs STAT4 to the development of lupus nephritis. J Immunol 170(9):4818-4825.
    • (2003) J Immunol , vol.170 , Issue.9 , pp. 4818-4825
    • Singh, R.R.1
  • 32
    • 1842417145 scopus 로고    scopus 로고
    • Constitutive expression of interleukin (IL)-4 in vivo causes auto-immune-type disorders in mice
    • Erb KJ, et al. (1997) Constitutive expression of interleukin (IL)-4 in vivo causes auto-immune-type disorders in mice. J Exp Med 185(2):329-339.
    • (1997) J Exp Med , vol.185 , Issue.2 , pp. 329-339
    • Erb, K.J.1
  • 33
    • 0037089624 scopus 로고    scopus 로고
    • Interleukin 4 reduces expression of inhibitory receptors on B cells and abolishes CD22 and Fc gamma RII-mediated B cell suppression
    • Rudge EU, Cutler AJ, Pritchard NR, Smith KGC (2002) Interleukin 4 reduces expression of inhibitory receptors on B cells and abolishes CD22 and Fc gamma RII-mediated B cell suppression. J Exp Med 195(8):1079-1085.
    • (2002) J Exp Med , vol.195 , Issue.8 , pp. 1079-1085
    • Rudge, E.U.1    Cutler, A.J.2    Pritchard, N.R.3    Smith, K.G.C.4
  • 34
    • 0026651551 scopus 로고
    • IL-4 down-regulates the surface expression of CD5 on B cells and inhibits spontaneous immunoglobulin and IgM-rheumatoid factor production in patients with rheumatoid arthritis
    • Hidaka T, et al. (1992) IL-4 down-regulates the surface expression of CD5 on B cells and inhibits spontaneous immunoglobulin and IgM-rheumatoid factor production in patients with rheumatoid arthritis. Clin Exp Immunol 89(2):223-229.
    • (1992) Clin Exp Immunol , vol.89 , Issue.2 , pp. 223-229
    • Hidaka, T.1
  • 35
    • 79957701773 scopus 로고    scopus 로고
    • Gammadelta intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface
    • Ismail AS, et al. (2011) Gammadelta intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface. Proc Natl Acad Sci USA 108(21):8743-8748.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.21 , pp. 8743-8748
    • Ismail, A.S.1
  • 36
    • 0017651982 scopus 로고
    • Abnormal polyclonal B cell activation in NZB/NZW F1 mice
    • Cohen PL, Ziff M (1977) Abnormal polyclonal B cell activation in NZB/NZW F1 mice. J Immunol 119(4):1534-1537.
    • (1977) J Immunol , vol.119 , Issue.4 , pp. 1534-1537
    • Cohen, P.L.1    Ziff, M.2
  • 38
    • 0018954048 scopus 로고
    • Polyclonal B cell activation and autoimmunity in New Zealand mice. I. Natural thymocytotoxic autoantibody (NTA)
    • Hirose S, Maruyama N, Ohta K, Shirai T (1980) Polyclonal B cell activation and autoimmunity in New Zealand mice. I. Natural thymocytotoxic autoantibody (NTA). J Immunol 125(2):610-615.
    • (1980) J Immunol , vol.125 , Issue.2 , pp. 610-615
    • Hirose, S.1    Maruyama, N.2    Ohta, K.3    Shirai, T.4
  • 39
    • 0018165154 scopus 로고
    • Increased spontaneous polyclonal activation of B lymphocytes in mice with spontaneous autoimmune disease
    • Izui S, McConahey PJ, Dixon FJ (1978) Increased spontaneous polyclonal activation of B lymphocytes in mice with spontaneous autoimmune disease. J Immunol 121(6):2213-2219.
    • (1978) J Immunol , vol.121 , Issue.6 , pp. 2213-2219
    • Izui, S.1    McConahey, P.J.2    Dixon, F.J.3
  • 40
    • 0031052817 scopus 로고    scopus 로고
    • A novel subset of adult gamma delta thymocytes that secretes a distinct pattern of cytokines and expresses a very restricted T cell receptor repertoire
    • Azuara V, Levraud JP, Lembezat MP, Pereira P (1997) A novel subset of adult gamma delta thymocytes that secretes a distinct pattern of cytokines and expresses a very restricted T cell receptor repertoire. Eur J Immunol 27(2):544-553.
    • (1997) Eur J Immunol , vol.27 , Issue.2 , pp. 544-553
    • Azuara, V.1    Levraud, J.P.2    Lembezat, M.P.3    Pereira, P.4
  • 41
    • 0042430409 scopus 로고    scopus 로고
    • Most IL-4-producing gamma delta thymocytes of adult mice originate from fetal precursors
    • Grigoriadou K, Boucontet L, Pereira P (2003) Most IL-4-producing gamma delta thymocytes of adult mice originate from fetal precursors. J Immunol 171(5):2413-2420.
    • (2003) J Immunol , vol.171 , Issue.5 , pp. 2413-2420
    • Grigoriadou, K.1    Boucontet, L.2    Pereira, P.3
  • 42
    • 0032738991 scopus 로고    scopus 로고
    • Development of an assay to measure in vivo cytokine production in the mouse
    • Finkelman FD, Morris SC (1999) Development of an assay to measure in vivo cytokine production in the mouse. Int Immunol 11(11):1811-1818.
    • (1999) Int Immunol , vol.11 , Issue.11 , pp. 1811-1818
    • Finkelman, F.D.1    Morris, S.C.2
  • 43
    • 0037103246 scopus 로고    scopus 로고
    • IL-4 promotes Stat6-dependent survival of autoreactive B cells in vivo without inducing autoantibody production
    • Morris SC, Dragula NL, Finkelman FD (2002) IL-4 promotes Stat6-dependent survival of autoreactive B cells in vivo without inducing autoantibody production. J Immunol 169(4):1696-1704.
    • (2002) J Immunol , vol.169 , Issue.4 , pp. 1696-1704
    • Morris, S.C.1    Dragula, N.L.2    Finkelman, F.D.3
  • 44
    • 15044343705 scopus 로고    scopus 로고
    • Interleukin-4 produces a breakdown of tolerance in vivo with autoantibody formation and tissue damage
    • Foote LC, et al. (2004) Interleukin-4 produces a breakdown of tolerance in vivo with autoantibody formation and tissue damage. Autoimmunity 37(8):569-577.
    • (2004) Autoimmunity , vol.37 , Issue.8 , pp. 569-577
    • Foote, L.C.1
  • 45
    • 84902153485 scopus 로고    scopus 로고
    • IL-4 regulates Bim expression and promotes B cell maturation in synergy with BAFF conferring resistance to cell death at negative selection checkpoints
    • Granato A, Hayashi EA, Baptista BJ, Bellio M, Nobrega A (2014) IL-4 regulates Bim expression and promotes B cell maturation in synergy with BAFF conferring resistance to cell death at negative selection checkpoints. J Immunol 192(12):5761-5775.
    • (2014) J Immunol , vol.192 , Issue.12 , pp. 5761-5775
    • Granato, A.1    Hayashi, E.A.2    Baptista, B.J.3    Bellio, M.4    Nobrega, A.5
  • 46
    • 80053065912 scopus 로고    scopus 로고
    • Cytoplasmic Ig alpha serine/threonines fine-tune Ig alpha tyrosine phosphorylation and limit bone marrow plasma cell formation
    • Patterson HC, et al. (2011) Cytoplasmic Ig alpha serine/threonines fine-tune Ig alpha tyrosine phosphorylation and limit bone marrow plasma cell formation. J Immunol 187(6):2853-2858.
    • (2011) J Immunol , vol.187 , Issue.6 , pp. 2853-2858
    • Patterson, H.C.1
  • 47
    • 0345016363 scopus 로고    scopus 로고
    • Chromatin specificity of anti-double-stranded DNA antibodies and a role for Arg residues in the third complementarity-determining region of the heavy chain
    • Guth AM, Zhang X, Smith D, Detanico T, Wysocki LJ (2003) Chromatin specificity of anti-double-stranded DNA antibodies and a role for Arg residues in the third complementarity-determining region of the heavy chain. J Immunol 171(11):6260-6266.
    • (2003) J Immunol , vol.171 , Issue.11 , pp. 6260-6266
    • Guth, A.M.1    Zhang, X.2    Smith, D.3    Detanico, T.4    Wysocki, L.J.5
  • 48
    • 20044375381 scopus 로고    scopus 로고
    • Mismatched antigen prepares gamma delta T cells for suppression of airway hyperresponsiveness
    • Jin N, et al. (2005) Mismatched antigen prepares gamma delta T cells for suppression of airway hyperresponsiveness. J Immunol 174(5):2671-2679.
    • (2005) J Immunol , vol.174 , Issue.5 , pp. 2671-2679
    • Jin, N.1
  • 49
    • 0022475348 scopus 로고
    • Diversity of murine gamma genes and expression in fetal and adult T lymphocytes
    • Heilig JS, Tonegawa S (1986) Diversity of murine gamma genes and expression in fetal and adult T lymphocytes. Nature 322(6082):836-840.
    • (1986) Nature , vol.322 , Issue.6082 , pp. 836-840
    • Heilig, J.S.1    Tonegawa, S.2
  • 50
    • 0024535530 scopus 로고
    • Characterization of a monoclonal antibody which detects all murine αβ T cell receptors
    • Kubo RT, Born W, Kappler JW, Marrack P, Pigeon M (1989) Characterization of a monoclonal antibody which detects all murine αβ T cell receptors. J Immunol 142(8):2736-2742.
    • (1989) J Immunol , vol.142 , Issue.8 , pp. 2736-2742
    • Kubo, R.T.1    Born, W.2    Kappler, J.W.3    Marrack, P.4    Pigeon, M.5
  • 51
    • 0025120214 scopus 로고
    • Self-reactive γδ T cells are eliminated in the thymus
    • Dent AL, et al. (1990) Self-reactive γδ T cells are eliminated in the thymus. Nature 343(6260):714-719.
    • (1990) Nature , vol.343 , Issue.6260 , pp. 714-719
    • Dent, A.L.1
  • 52
    • 0028785546 scopus 로고
    • Ontogenic development and tissue distribution of V γ 1-expressing γ/δ T lymphocytes in normal mice
    • Pereira P, Gerber D, Huang SY, Tonegawa S (1995) Ontogenic development and tissue distribution of V γ 1-expressing γ/δ T lymphocytes in normal mice. J Exp Med 182(6):1921-1930.
    • (1995) J Exp Med , vol.182 , Issue.6 , pp. 1921-1930
    • Pereira, P.1    Gerber, D.2    Huang, S.Y.3    Tonegawa, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.