Purkinje neuron Ca2+ influx reduction rescues ataxia in SCA28 model

Journal of Clinical Investigation

Volumn 125, Issue 1, 2015, Pages 263-274

  Maltecca, Francesca ^a   Baseggio, Elisa ^a   Consolato, Francesco ^a   Mazza, Davide ^a   Podini, Paola ^b   Young, Samuel M ^c   Drago, Ilaria ^d,e   Bahr, Ben A ^f   Puliti, Aldamaria ^g,h   Codazzi, Franca ^b   Quattrini, Angelo ^b   Casari, Giorgio ^a  

^a VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c MAX PLANCK FLORIDA INSTITUTE FOR NEUROSCIENCE   (United States)

^d UNIVERSITY OF PADOVA   (Italy)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

^f UNIVERSITY OF NORTH CAROLINA AT PEMBROKE   (United States)

^g G GASLINI INSTITUTE   (Italy)

^h UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AFG3L2 PROTEIN; CALCIUM; CEFTRIAXONE; METABOTROPIC RECEPTOR 1; MITOCHONDRIAL PROTEIN; PROTEINASE; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE DEPENDENT PROTEINASE; AFG3L2 PROTEIN, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL MEMBRANE DEPOLARIZATION; CELL ORGANELLE; CEREBELLAR ATAXIA; CONTROLLED STUDY; CYTOPLASM; GENE SILENCING; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOUSE; NEUROPATHOLOGY; NONHUMAN; PURKINJE CELL; SPINOCEREBELLAR ATAXIA TYPE 28; ANIMAL; BAGG ALBINO MOUSE; CALCIUM SIGNALING; DENDRITE; DISEASE MODEL; DRUG SCREENING; GENETICS; HUMAN; METABOLISM; PATHOLOGY; PHYSIOLOGY; PSYCHOMOTOR PERFORMANCE; SPINOCEREBELLAR DEGENERATIONS; TRANSGENIC MOUSE;

ANIMALS; ATP-DEPENDENT PROTEASES; CALCIUM; CALCIUM SIGNALING; CEFTRIAXONE; DENDRITES; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; HUMANS; MICE, INBRED BALB C; MICE, TRANSGENIC; MITOCHONDRIA; PSYCHOMOTOR PERFORMANCE; PURKINJE CELLS; SPINOCEREBELLAR DEGENERATIONS;

EID: 84920438196     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI74770     Document Type: Article

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