Deregulation of glyceraldehyde-3-phosphate dehydrogenase expression during tumor progression of human cutaneous melanoma

Anticancer Research

Volumn 35, Issue 1, 2015, Pages 439-444

  Ramos, David ^a   Pellín Carcelén, Ana ^a   Agustí, Jaime ^a   Murgui, Amelia ^a   Jordá, Esperanza ^b   Pellín, Antonio ^a   Monteagudo, Carlos ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

Author keywords

GAPDH; Immunohistochemistry; Melanoma; MRNA expression; Prognosis

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA;

ARTICLE; CONTROLLED STUDY; CUTANEOUS MELANOMA; DEREGULATION; DISTANT METASTASIS; DNA SEQUENCE; EXON; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; METASTATIC MELANOMA; POINT MUTATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TUMOR GROWTH; DISEASE COURSE; ENZYMOLOGY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; MELANOMA; METABOLISM; PATHOLOGY; PROGNOSIS; SECONDARY; SKIN TUMOR;

DISEASE PROGRESSION; GENE EXPRESSION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; LYMPHATIC METASTASIS; MELANOMA; PROGNOSIS; SKIN NEOPLASMS;

EID: 84920426306     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Thellin O, Zorzi W, Lakaye B. De Borman B, Coumans B, Hennen G, Grisar T, Igout A and Heinen E: Housekeeping genes as internal standards: use and limits. J Biotechnol 75 (2-3): 291-295, 1999.
2. Goidin D, Mamessier A, Staquet MJ, Schmitt D and Berthier- Vergnes O: Ribosomal 18S RNA prevails over glyceraldehyde-3- phosphate dehydrogenase and β-actin genes as internal standard for quantitative comparison of mRNA levels in invasive and noninvasive human melanoma cell subpopulations. Anal Biochem 295 (1): 17-21, 2001.
3. Bas A, Forsberg G, Hammarstrom S and Hammarstrom ML: Utility of the housekeeping genes 18S rRNA, β-actin and glyceraldehyde-3-phosphate dehydrogenase for normalization in real-time quantitative reverse transcriptase-polymerase chain reaction analysis of gene expression in human T lymphocytes. Scand J Immunol 59 (6): 566-573, 2004.
4. Sirover MA: Role of the glycolytic protein, glyceraldehyde-3- phosphate dehydrogenase, in normal cell function and cell pathology. J Cell Biochem 66 (2): 133-140, 1997.
5. Sirover MA: New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells. J Cell Biochem 95 (1): 45-52, 2005.
6. Sedlak TW and Snyder SH: Messenger molecules and cell death: therapeutic implications. JAMA 295 (1): 81-89, 2006.
7. Chuang DM, Hough C and Senatorov VV: Glyceraldehyde-3- phosphate dehydrogenase, apoptosis, and neurodegenerative diseases. Ann Rev Pharmacol Toxicol 45: 269-290, 2005.
8. Colell A, Green DR and Ricci JE: Novel roles for GAPDH in cell death and carcinogenesis. Cell Death Differ 16 (12): 1573-1581, 2009.
9. Tristan C, Shahani N, Sedlak TW and Sawa A: The diverse functions of GAPDH: views from different subcellular compartments. Cell Signal 23 (2): 317-323, 2011.
10. Goldsworthy SM, Goldsworthy TL, Sprankle CS and Butterworth BE: Variation in expression of genes used for normalization of northern blots after induction of cell proliferation. Cell Prolif 26 (6): 511-518, 1993.
11. Bustin SA: Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): Trends and problems. J Mol Endocrinol 29 (1): 23-39, 2002.
12. Warburg O: On the origin of cancer cells. Science 23 (3191): 309-314, 1956.
13. Warburg O: On respiratory impairment in cancer cells. Science 124 (3215): 269-270, 1956.
14. Giricz O, Lauer-Fields JL and Fields GB: The normalization of gene expression data in melanoma: investigating the use of glyceraldahyde 3-phosphate dehydrogenase and 18S ribosomal RNA as internal reference genes for quantitative real-time PCR. Anal Biochem 380 (1): 137-139, 2008.
15. Revillion F, Pawlowski V and Hornez L: Glyceraldehyde-3- phosphate dehydrogenase gene expression in human breast cancer. Eur J Cancer 36 (8): 1038-1042, 2000.
16. Tokunaga K, Nakamura Y, Sakata K, Fujimori K, Ohkubo M, Sawada K and Sakiyama S: Enhanced expression of a glyceraldehyde-3-phosphate dehydrogenase gene in human lung cancers. Cancer Res 47 (21): 5616-5619, 1987.
17. Schek N, Hall BL and Finn OJ: Increased glyceraldehyde-3- phosphate dehydrogenase gene expression in human pancreatic adenocarcinoma. Cancer Res 48 (22): 6354-6359, 1988.
18. Vila MR, Nicolas A, Morote J and Meseguer A: Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reaction. Cancer 89 (1): 152-164, 2000.
19. Seykora JT, Jih D, Elenitsas R, Horng WH and Elder DE: Gene expression profiling of melanocytic lesions. Am J Dermatopathol 25 (1): 6-11, 2003.
20. Zhou J, Dudley ME, Rosenberg SA and Robbins PF: Persistence of multiple tumor-specific T-cell clones is associated with complete tumor regression in a melanoma patient receiving adoptive cell transfer therapy. J Immunother 28 (1): 53-62, 2005.
21. Balch CM, Buzaid AC, Soong SJ, Atkins MB, Cascinelli N, Coit DG, Fleming ID, Gershenwald JE, Houghton A Jr, Kirkwood JM, McMasters KM, Mihm MF, Morton DL, Reintgen DS, Ross MI, Sober A, Thompson JA and Thompson JF: Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma. J Clin Oncol 19 (16): 3635-3648, 2001.
22. Balch CM, Gershenwald JE, Soong SJ, Thompson JF, Atkins MB, Byrd DR, Buzaid AC, Cochran AJ, Coit DG, Ding S, Eggermont AM, Flaherty KT, Gimotty PA, Kirkwood JM, McMasters KM, Mihm MC Jr., Morton DL, Ross MI, Sober AJ and Sondak VK: Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol 27 (36): 6199-6206, 2009.
23. Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2- δδCt method. Methods 25 (4): 402-408, 2001.
24. Thompson JF, Scolier RA and Kefford RF. Cutaneous melanoma. Lancet 365 (9460): 687-701, 2005.
25. Warburg O, Wind F and Negelein E: The metabolism of tumors in the body. J Gen Physiol 8 (6): 519-530, 1927.
26. Vander Heiden MG, Cantley LC and Thompson CB: Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324 (5930): 1029-1030, 2009.
27. Falkenius J, Lundberg J, Johansson H, Frostvik-Stolt, J. Lundeberg, Hansson J and Egyhazi S: A gene expression profile associated with clinical outcome in stage III melanoma. J Clin Oncol 29 (suppl; abstr): 8551, 2011.
28. Engel M, Seifert M, Theisinger B, Seyfert U and Welter C: Glyceraldehyde-3-phosphate dehydrogenase and Nm23- H1/nucleoside diphosphate kinase A. Two old enzymes combine for the novel Nm23 protein phosphotransferase function. J Biol Chem 273 (32): 20058-20065, 1998.
29. Engel M, Mazurek S, Eigenbrodt E and Welter C: Phosphoglycerate mutase-derived polypeptide inhibits glycolytic flux and induces cell growth arrest in tumor cell lines. J Biol Chem 279 (34): 35803-35812, 2004.
30. Steeg PS, Bevilacqua G, Kopper L, Thorgeirsson UP, Talmadge JE, Liotta LA and Sobel ME: Evidence for a novel gene associated with low tumor metastatic potential. J Natl Cancer Inst 80 (3): 200-204, 1998.
31. Hartsough MT and Steeg PS: Nm23/nucleoside diphosphate kinase in human cancers. J Bioenerg Biomembr 32 (3): 301-308, 2000.
32. Hartsough MT, Morrison DK, Salerno M, Palmieri D, Ouatas T, Mair M, Patrick J and Steeg PS: Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway. J Biol Chem 277 (35): 32389-32399, 2002.
33. Ouatas T, Salerno M, Palmieri D and Steeg PS: Basic and translational advances in cancer metastasis: Nm23. J Bioenerg Biomembr 35 (1): 73-79, 2003.
34. McDermott NC, Milburn C, Curran B, Kay EW, Barry Walsh C and Leader MB: Immunohistochemical expression of NM23 in primary invasive malignant melanoma is predictive of survival outcome. J Pathol 190 (2): 157-162, 2000.
35. Lee CS, Pirdas A and Lee MW: Immunohistochemical demonstration of the NM23-H1 gene product in human malignant melanoma and Spitz nevi. Pathology 28 (3): 220-224, 1996.
36. Sarris M, Scolyer RA, Konopka M, Thompson JF, Harper CG and Lee CS: Cytoplasmic expression of NM23 predicts the potential for cerebral metastasis in patients with primary cutaneous melanoma. Melanoma Res 14 (1): 23-27, 2004.
37. Aerts JL, Gonzales MI, Topalian SL, Chinnasamy N, Morgan RA and Topalian SL: Selection of appropriate control genes to assess expression of tumor antigens using real-time RT-PCR. Biotechniques 36 (1): 84-91, 2004.