Killing of melanoma cells and their metastases by human lactoferricin derivatives requires interaction with the cancer marker phosphatidylserine

BioMetals

Volumn 27, Issue 5, 2014, Pages 981-997

  Riedl, Sabrina ^a   Rinner, Beate ^b   Schaider, Helmut ^b,c   Lohner, Karl ^a   Zweytick, Dagmar ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

^c UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Cancer therapy; Cell membrane permeabilization; Lactoferricin derivatives; Liposomes; Melanoma; Membrane biophysics; Peptides; Phosphatidylserine

Indexed keywords

LACTOFERRICIN; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLSERINE; TRYPTOPHAN; ANTINEOPLASTIC AGENT; LACTOFERRICIN B; LACTOFERRIN; PEPTIDE FRAGMENT;

ACYLATION; ANTINEOPLASTIC ACTIVITY; BETA SHEET; CANCER CELL; CELL KILLING; CELL MEMBRANE; CIRCULAR DICHROISM; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; MELANOCYTE; MELANOMA CELL; METASTASIS; PERMEABILITY; PROTEIN SECONDARY STRUCTURE; REVIEW; CELL DEATH; CELL MEMBRANE PERMEABILITY; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; MELANOMA; METABOLISM; NEOPLASM METASTASIS; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL DEATH; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; HUMANS; LACTOFERRIN; MELANOCYTES; MELANOMA; MODELS, MOLECULAR; NEOPLASM METASTASIS; PEPTIDE FRAGMENTS; PHOSPHATIDYLSERINES; PROTEIN STRUCTURE, SECONDARY;

EID: 84920279829     PISSN: 09660844     EISSN: 15728773     Source Type: Journal    
DOI: 10.1007/s10534-014-9749-0     Document Type: Review

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