Comparison of proteomic and metabolomic profiles of mutants of the mitochondrial respiratory chain in Caenorhabditis elegans

Mitochondrion

Volumn 20, Issue , 2015, Pages 95-102

  Morgan, P G ^a,b   Higdon, R ^b,c,d   Kolker, N ^b,d,g   Bauman, A T ^c   Ilkayeva, O ^f   Newgard, C B ^f   Kolker, E ^a,b,c,d,e   Steele, L M ^b   Sedensky, M M ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^c Bioinformatics and High throughput Analysis Laboratory   (United States)

^d Data Enabled Life Sciences Alliance (DELSA Global)   (United States)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^f DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g NORTHEASTERN UNIVERSITY   (United States)

Author keywords

C. elegans; Gene expression; Genetics; Metabolomics; Mitochondria; Proteomics

Indexed keywords

CYTOCHROME C OXIDASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); UBIQUINOL CYTOCHROME C REDUCTASE; UBIQUINONE; CAENORHABDITIS ELEGANS PROTEIN; MITOCHONDRIAL PROTEIN; MULTIENZYME COMPLEX; PROTEOME;

ANIMAL CELL; ARTICLE; CAENORHABDITIS ELEGANS; CLK 1 GENE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE MODEL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME SYNTHESIS; GAS 1 GENE; GENE EXPRESSION; GENE MUTATION; INTRACELLULAR SIGNALING; METABOLOMICS; MEV 1 GENE; MISSENSE MUTATION; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL RESPIRATION; MUTATIONAL ANALYSIS; NONHUMAN; PROCESS DEVELOPMENT; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEOMICS; RESPIRATORY CHAIN; ANIMAL; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLOME; MITOCHONDRION; MUTATION;

CAENORHABDITIS ELEGANS; MAMMALIA;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; METABOLOME; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUTATION; PROTEOME;

EID: 84920273684     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/j.mito.2014.12.004     Document Type: Article

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