Correlation of plasma brain-derived neurotrophic factor and metabolic profiles in drug-naïve patients with bipolar II disorder after a twelve-week pharmacological intervention

Acta Psychiatrica Scandinavica

Volumn 131, Issue 2, 2015, Pages 120-128

  Lee, S Y ^a,b   Chen, S L ^b,c   Chang, Y H ^b   Chen, P S ^b   Huang, S Y ^d   Tzeng, N S ^d   Wang, C L ^b   Wang, L J ^e   Lee, I H ^b   Wang, T Y ^f   Chen, K C ^b,g   Yang, Y K ^b,h   Hong, J S ⁱ   Lu, R B ^b,c,g,j,k  

^a KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^e CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^f Tainan Hospital   (Taiwan)

^g NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

^h NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

ⁱ NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^j Institute of Behavioral Medicine   (Taiwan)

^k NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

more..

Author keywords

Bipolar II disorder; Body mass index; Brain derived neurotrophic factor; Metabolic syndrome

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CHOLESTEROL; FLUOXETINE; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LORAZEPAM; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; VALPROIC ACID; BRAIN-DERIVED NEUROTROPHIC FACTOR; BRAIN-DERIVED NEUROTROPHIC FACTOR, HUMAN; LIPOPROTEINS, LDL;

ARTICLE; BIPOLAR II DISORDER; BODY MASS; DIET RESTRICTION; GLUCOSE BLOOD LEVEL; HAMILTON DEPRESSION RATING SCALE; HUMAN; MAJOR CLINICAL STUDY; METABOLIC PARAMETERS; PROTEIN BLOOD LEVEL; YOUNG MANIA RATING SCALE; ADULT; AFFECT; BIPOLAR DISORDER; BLOOD; BODY MASS INDEX; CLINICAL TRIAL; DRUG EFFECTS; FEMALE; HUMANS; LINEAR MODELS; LONGITUDINAL STUDIES; MALE; METABOLIC SYNDROME X; METABOLISM; PSYCHIATRIC STATUS RATING SCALES; PSYCHOLOGY; TREATMENT OUTCOME;

ADULT; AFFECT; BIPOLAR DISORDER; BODY MASS INDEX; BRAIN-DERIVED NEUROTROPHIC FACTOR; CHOLESTEROL; FEMALE; FLUOXETINE; HUMANS; LINEAR MODELS; LIPOPROTEINS, LDL; LONGITUDINAL STUDIES; LORAZEPAM; MALE; METABOLIC SYNDROME X; PSYCHIATRIC STATUS RATING SCALES; TREATMENT OUTCOME; VALPROIC ACID;

EID: 84920261578     PISSN: 0001690X     EISSN: 16000447     Source Type: Journal    
DOI: 10.1111/acps.12324     Document Type: Article

References (67)

1. Benazzi F, Akiskal HS. Refining the evaluation of bipolar II: beyond the strict SCID-CV guidelines for hypomania. J Affect Disord 2003;73:33-38.
2. Angst J. The bipolar spectrum. Br J Psychiatry 2007;190:189-191.
3. Vieta E, Suppes T. Bipolar II disorder: arguments for and against a distinct diagnostic entity. Bipolar Disord 2008;10:163-178.
4. Judd LL, Akiskal HS, Schettler PJ, et al. The comparative clinical phenotype and long term longitudinal episode course of bipolar I and II: a clinical spectrum or distinct disorders? J Affect Disord 2003;73:19-32.
5. de Barros Pellegrinelli K, de O Costa LF, Silval KI, et al. Efficacy of psychoeducation on symptomatic and functional recovery in bipolar disorder. Acta Psychiatr Scand 2013;127:153-158.
6. Akiskal H. Targeting suicide prevention to modifiable risk factors: has bipolar II been overlooked? Acta Psychiatr Scand 2007;116:395-402.
7. Drancourt N, Etain B, Lajnef M, et al. Duration of untreated bipolar disorder: missed opportunities on the long road to optimal treatment. Acta Psychiatr Scand 2013;127:136-144.
8. Ghaemi SN, Boiman E, Goodwin FK. Insight and outcome in bipolar, unipolar, and anxiety disorders. Compr Psychiatry 2000;41:167-171.
9. Soeiro-De-souza MG, Dias VV, Figueira ML, et al. Translating neurotrophic and cellular plasticity: from pathophysiology to improved therapeutics for bipolar disorder. Acta Psychiatr Scand 2012;126:332-341.
10. Lim CS, Baldessarini RJ, Vieta E, Yucel M, Bora E, Sim K. Longitudinal neuroimaging and neuropsychological changes in bipolar disorder patients: review of the evidence. Neurosci Biobehav Rev 2013;37:418-435.
11. Cotman CW, Berchtold NC. Exercise: a behavioral intervention to enhance brain health and plasticity. Trends Neurosci 2002;25:295-301.
12. Duman RS. Synaptic plasticity and mood disorders. Mol Psychiatry 2002;7(Suppl 1):S29-S34.
13. Fernandes BS, Gama CS, Kauer-Sant'anna M, Lobato MI, Belmonte-De-Abreu P, Kapczinski F. Serum brain-derived neurotrophic factor in bipolar and unipolar depression: a potential adjunctive tool for differential diagnosis. J Psychiatr Res 2009;43:1200-1204.
14. de Oliveira GS, Cereser KM, Fernandes BS, et al. Decreased brain-derived neurotrophic factor in medicated and drug-free bipolar patients. J Psychiatr Res 2009;43:1171-1174.
15. Machado-Vieira R, Dietrich MO, Leke R, et al. Decreased plasma brain derived neurotrophic factor levels in unmedicated bipolar patients during manic episode. Biol Psychiatry 2007;61:142-144.
16. Barbosa IG, Huguet RB, Mendonca VA, et al. Increased plasma levels of brain-derived neurotrophic factor in patients with long-term bipolar disorder. Neurosci Lett 2010;475:95-98.
17. Barbosa IG, Rocha NP, Miranda AS, et al. Increased BDNF levels in long-term bipolar disorder patients. Rev Bras Psiquiatr 2013;35:67-69.
18. Grande I, Magalhaes PV, Chendo I, et al. Val66Met polymorphism and serum brain-derived neurotrophic factor in bipolar disorder: an open-label trial. Acta Psychiatr Scand 2014;129:393-400.
19. Barbosa IG, Rocha NP, Huguet RB, et al. Executive dysfunction in euthymic bipolar disorder patients and its association with plasma biomarkers. J Affect Disord 2012;137:151-155.
20. Suwalska A, Sobieska M, Rybakowski JK. Serum brain-derived neurotrophic factor in euthymic bipolar patients on prophylactic lithium therapy. Neuropsychobiology 2010;62:229-234.
21. Bocchio-Chiavetto L, Zanardini R, Bortolomasi M, et al. Electroconvulsive Therapy (ECT) increases serum Brain Derived Neurotrophic Factor (BDNF) in drug resistant depressed patients. Eur Neuropsychopharmacol 2006;16: 620-624.
22. Shimizu E, Hashimoto K, Okamura N, et al. Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants. Biol Psychiatry 2003;54:70-75.
23. Malhi GS, Tanious M, Das P, Coulston CM, Berk M. Potential mechanisms of action of lithium in bipolar disorder. Current understanding. CNS drugs 2013;27:135-153.
24. Sen S, Duman R, Sanacora G. Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biol Psychiatry 2008;64:527-532.
25. Ricken R, Adli M, Lange C, et al. Brain-derived neurotrophic factor serum concentrations in acute depressive patients increase during lithium augmentation of antidepressants. J Clin Psychopharmacol 2013;33:806-809.
26. Grande I, Kapczinski F, Stertz L, et al. Peripheral brain-derived neurotrophic factor changes along treatment with extended release quetiapine during acute mood episodes: an open-label trial in drug-free patients with bipolar disorder. J Psychiatr Res 2012;46:1511-1514.
27. Fernandes BS, Gama CS, Cereser KM, et al. Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: a systematic review and meta-regression analysis. J Psychiatr Res 2011;45:995-1004.
28. Karege F, Bondolfi G, Gervasoni N, Schwald M, Aubry JM, Bertschy G. Low brain-derived neurotrophic factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity. Biol Psychiatry 2005;57:1068-1072.
29. Cirulli F, Francia N, Branchi I, et al. Changes in plasma levels of BDNF and NGF reveal a gender-selective vulnerability to early adversity in rhesus macaques. Psychoneuroendocrinology 2009;34:172-180.
30. Pan W, Banks WA, Fasold MB, Bluth J, Kastin AJ. Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 1998;37:1553-1561.
31. Laske C, Stransky E, Leyhe T, et al. Decreased brain-derived neurotrophic factor (BDNF)- and beta-thromboglobulin (beta-TG)- blood levels in Alzheimer's disease. Thromb Haemost 2006;96:102-103.
32. Taylor V, Macqueen G. Associations between bipolar disorder and metabolic syndrome: A review. J Clin Psychiatry 2006;67:1034-1041.
33. Fagiolini A, Frank E, Scott JA, Turkin S, Kupfer DJ. Metabolic syndrome in bipolar disorder: findings from the Bipolar Disorder Center for Pennsylvanians. Bipolar Disord 2005;7:424-430.
34. Lyons WE, Mamounas LA, Ricaurte GA, et al. Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities. Proc Natl Acad Sci USA 1999;96:15239-15244.
35. Bullo M, Peeraully MR, Trayhurn P, Folch J, Salas-Salvado J. Circulating nerve growth factor levels in relation to obesity and the metabolic syndrome in women. Eur J Endocrinol 2007;157:303-310.
36. Manni L, Nikolova V, Vyagova D, Chaldakov GN, Aloe L. Reduced plasma levels of NGF and BDNF in patients with acute coronary syndromes. Int J Cardiol 2005;102:169-171.
37. Krabbe KS, Nielsen AR, Krogh-Madsen R, et al. Brain-derived neurotrophic factor (BDNF) and type 2 diabetes. Diabetologia 2007;50:431-438.
38. Chaldakov GN, Fiore M, Stankulov IS, et al. Neurotrophin presence in human coronary atherosclerosis and metabolic syndrome: a role for NGF and BDNF in cardiovascular disease? Prog Brain Res 2004;146:279-289.
39. Corripio R, Gonzalez-Clemente JM, Jacobo PS, et al. Plasma brain-derived neurotrophic factor in prepubertal obese children: results from a 2-year lifestyle intervention programme. Clin Endocrinol 2012;77:715-720.
40. Araya AV, Orellana X, Espinoza J. Evaluation of the effect of caloric restriction on serum BDNF in overweight and obese subjects: preliminary evidences. Endocrine 2008;33: 300-304.
41. Endicott J, Spitzer RL. A diagnostic interview: the schedule for affective disorders and schizophrenia. Arch Gen Psychiatry 1978;35:837-844.
42. Huang SY, Lin WW, Ko HC, et al. Possible interaction of alcohol dehydrogenase and aldehyde dehydrogenase genes with the dopamine D2 receptor gene in anxiety-depressive alcohol dependence. Alcohol Clin Exp Res 2004;28:374-384.
43. Angst J, Gamma A, Bowden CL, et al. Diagnostic criteria for bipolarity based on an international sample of 5635 patients with DSM-IV major depressive episodes. Eur Arch Psychiatry Clin Neurosci 2012;262:3-11.
44. Angst J, Azorin JM, Bowden CL, et al. Prevalence and characteristics of undiagnosed bipolar disorders in patients with a major depressive episode: the BRIDGE study. Arch Gen Psychiatry 2011;68:791-798.
45. Young RC, Biggs JT, Ziegler VE, Meyer DA. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry 1978;133:429-435.
46. Hamilton M. Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 1967;6:278-296.
47. Zeger SL, Liang KY, Albert PS. Models for longitudinal data: a generalized estimating equation approach. Biometrics 1988;44:1049-1060.
48. Shen CW, Chen YH. Model selection for generalized estimating equations accommodating dropout missingness. Biometrics 2012;68:1046-1054.
49. Buchner A, Faul F, Erdfelder E. G-power: A Priori, Post Hoc, and Compromise Power Analyses for the Macintosh. Version 2.1.1. ed. Germany. University of Trier, Trier; 1996.
50. Faul F, Erdfelder E, Buchner A, Lang A. Statistical power analyses using G*Power 3.1: tests for correlation and regression analyses. Behav Res Methods 2009;41:1149-1160.
51. Golden E, Emiliano A, Maudsley S, et al. Circulating brain-derived neurotrophic factor and indices of metabolic and cardiovascular health: data from the Baltimore Longitudinal Study of Aging. PLoS ONE 2010;5:e10099.
52. Matthews VB, Astrom MB, Chan MH, et al. Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase. Diabetologia 2009;52:1409-1418.
53. Yamamoto H, Gurney ME. Human platelets contain brain-derived neurotrophic factor. J Neurosci 1990;10:3469-3478.
54. Lommatzsch M, Schloetcke K, Klotz J, et al. Brain-derived neurotrophic factor in platelets and airflow limitation in asthma. Am J Respir Crit Care Med 2005;171:115-120.
55. Merhi ZO, Minkoff H, Lambert-Messerlian GM, Macura J, Feldman J, Seifer DB. Plasma brain-derived neurotrophic factor in women after bariatric surgery: a pilot study. Fertil Steril 2009;91:1544-1548.
56. Kerschensteiner M, Gallmeier E, Behrens L, et al. Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation? J Exp Med 1999;189:865-870.
57. Beumer W, Drexhage RC, de Wit H, Versnel MA, Drexhage HA, Cohen D. Increased level of serum cytokines, chemokines and adipokines in patients with schizophrenia is associated with disease and metabolic syndrome. Psychoneuroendocrinology 2012;37:1901-1911.
58. Lin PY. State-dependent decrease in levels of brain-derived neurotrophic factor in bipolar disorder: a meta-analytic study. Neurosci Lett 2009;466:139-143.
59. Martin B, Pearson M, Kebejian L, et al. Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excess. Endocrinology 2007;148:4318-4333.
60. Schwarz E, Bahn S. Cerebrospinal fluid: identification of diagnostic markers for schizophrenia. Expert Rev Mol Diagn 2008;8:209-216.
61. Pillai A, Bruno D, Sarreal AS, et al. Plasma BDNF levels vary in relation to body weight in females. PLoS ONE 2012;7:e39358.
62. Pillai A, Kale A, Joshi S, et al. Decreased BDNF levels in CSF of drug-naive first-episode psychotic subjects: correlation with plasma BDNF and psychopathology. Int J Neuropsychopharmacol 2010;13:535-539.
63. Lommatzsch M, Zingler D, Schuhbaeck K, et al. The impact of age, weight and gender on BDNF levels in human platelets and plasma. Neurobiol Aging 2005;26:115-123.
64. Krabbe KS, Mortensen EL, Avlund K, et al. Brain-derived neurotrophic factor predicts mortality risk in older women. J Am Geriatr Soc 2009;57:1447-1452.
65. Radka SF, Holst PA, Fritsche M, Altar CA. Presence of brain-derived neurotrophic factor in brain and human and rat but not mouse serum detected by a sensitive and specific immunoassay. Brain Res 1996;709:122-301.
66. Bus BA, Molendijk ML, Penninx BJ, et al. Determinants of serum brain-derived neurotrophic factor. Psychoneuroendocrinology 2011;36:228-239.
67. Goldberg JF, Perlis RH, Bowden CL, et al. Manic symptoms during depressive episodes in 1380 patients with bipolar disorder: findings from the STEP-BD. Am J Psychiatry 2009;166:173-181.