-
1
-
-
79952459914
-
The human African trypanosomiasis control and surveillance programme of the World Health Organization 2000–2009: the way forward
-
Simarro PP, Diarra A, Ruiz Postigo JA, Franco JR, Jannin JG, (2011) The human African trypanosomiasis control and surveillance programme of the World Health Organization 2000–2009: the way forward. PLoS Negl Trop Dis 5: e1007.
-
(2011)
PLoS Negl Trop Dis
, vol.5
, pp. e1007
-
-
Simarro, P.P.1
Diarra, A.2
Ruiz Postigo, J.A.3
Franco, J.R.4
Jannin, J.G.5
-
2
-
-
77958502639
-
Chemotherapy of human African trypanosomiasis
-
Bacchi CJ, (2009) Chemotherapy of human African trypanosomiasis. Interdiscip Perspect Infect Dis 2009: 195040.
-
(2009)
Interdiscip Perspect Infect Dis
, vol.2009
, pp. 195040
-
-
Bacchi, C.J.1
-
3
-
-
84861909705
-
Update on field use of the available drugs for the chemotherapy of human African trypanosomiasis
-
Simarro PP, Franco J, Diarra A, Postigo JA, Jannin J, (2012) Update on field use of the available drugs for the chemotherapy of human African trypanosomiasis. Parasitology 139: 842–846.
-
(2012)
Parasitology
, vol.139
, pp. 842-846
-
-
Simarro, P.P.1
Franco, J.2
Diarra, A.3
Postigo, J.A.4
Jannin, J.5
-
4
-
-
67649635323
-
Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial
-
Priotto G, Kasparian S, Mutombo W, Ngouama D, Ghorashian S, et al. (2009) Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial. Lancet 374: 56–64.
-
(2009)
Lancet
, vol.374
, pp. 56-64
-
-
Priotto, G.1
Kasparian, S.2
Mutombo, W.3
Ngouama, D.4
Ghorashian, S.5
-
5
-
-
0034990047
-
The situation of sleeping sickness in Angola: a calamity
-
Stanghellini A, Josenando T, (2001) The situation of sleeping sickness in Angola: a calamity. Trop Med Int Health 6: 330–334.
-
(2001)
Trop Med Int Health
, vol.6
, pp. 330-334
-
-
Stanghellini, A.1
Josenando, T.2
-
6
-
-
0033161122
-
Echecs thérapeutiques du mélarsoprol parmi des patients traités au stade tardif de trypanosomose humaine africaine à T. b. gambiense en Ouganda
-
Legros D, Fournier C, Gastellu Etchegorry M, Maiso F, Szumilin E, (1999) Echecs thérapeutiques du mélarsoprol parmi des patients traités au stade tardif de trypanosomose humaine africaine à T. b. gambiense en Ouganda. Bull Soc Pathol Exot Fil 92: 171–172.
-
(1999)
Bull Soc Pathol Exot Fil
, vol.92
, pp. 171-172
-
-
Legros, D.1
Fournier, C.2
Gastellu Etchegorry, M.3
Maiso, F.4
Szumilin, E.5
-
7
-
-
0034777039
-
The phenomenon of treatment failures in human African trypanosomiasis
-
Brun R, Schumacher R, Schmid C, Kunz C, Burri C, (2001) The phenomenon of treatment failures in human African trypanosomiasis. Trop Med Int Health 6: 906–914.
-
(2001)
Trop Med Int Health
, vol.6
, pp. 906-914
-
-
Brun, R.1
Schumacher, R.2
Schmid, C.3
Kunz, C.4
Burri, C.5
-
8
-
-
75649107641
-
How to shorten patient follow-up after treatment for Trypanosoma brucei gambiense sleeping sickness?
-
Mumba Ngoyi D, Lejon V, Pyana P, Boelaert M, Ilunga M, et al. (2010) How to shorten patient follow-up after treatment for Trypanosoma brucei gambiense sleeping sickness? J Infect Dis 201: 453–463.
-
(2010)
J Infect Dis
, vol.201
, pp. 453-463
-
-
Mumba Ngoyi, D.1
Lejon, V.2
Pyana, P.3
Boelaert, M.4
Ilunga, M.5
-
9
-
-
35348915954
-
Genotypic and phenotypic characterization of Trypanosoma brucei gambiense isolates from Ibba, South Sudan, an area of high melarsoprol treatment failure
-
Maina N, Maina KJ, Mäser P, Brun R, (2007) Genotypic and phenotypic characterization of Trypanosoma brucei gambiense isolates from Ibba, South Sudan, an area of high melarsoprol treatment failure. Acta Trop 104: 84–90.
-
(2007)
Acta Trop
, vol.104
, pp. 84-90
-
-
Maina, N.1
Maina, K.J.2
Mäser, P.3
Brun, R.4
-
10
-
-
45249115279
-
High failure rates of melarsoprol for sleeping sickness, Democratic Republic of Congo
-
Robays J, Nyamowala G, Sese C, Kande Betu-Ku-Mesu V, Lutumba P, et al. (2008) High failure rates of melarsoprol for sleeping sickness, Democratic Republic of Congo. Em Inf Dis 14: 966–967.
-
(2008)
Em Inf Dis
, vol.14
, pp. 966-967
-
-
Robays, J.1
Nyamowala, G.2
Sese, C.3
Kande Betu-Ku-Mesu, V.4
Lutumba, P.5
-
11
-
-
0034985389
-
Melarsoprol refractory T. b. gambiense from Omugo, north-western Uganda
-
Matovu E, Enyaru JCK, Legros D, Schmid C, Seebeck T, et al. (2001) Melarsoprol refractory T. b. gambiense from Omugo, north-western Uganda. Trop Med Int Health 6: 407–411.
-
(2001)
Trop Med Int Health
, vol.6
, pp. 407-411
-
-
Matovu, E.1
Enyaru, J.C.K.2
Legros, D.3
Schmid, C.4
Seebeck, T.5
-
12
-
-
0034991804
-
Pharmacokinetic investigations in patients from northern Angola refractory to melarsoprol treatment
-
Burri C, Keiser J, (2001) Pharmacokinetic investigations in patients from northern Angola refractory to melarsoprol treatment. Trop Med Int Health 6: 412–420.
-
(2001)
Trop Med Int Health
, vol.6
, pp. 412-420
-
-
Burri, C.1
Keiser, J.2
-
13
-
-
36549036766
-
Detection of mutant P2 adenosine transporter (TbAT1) gene in Trypanosoma brucei gambiense isolates from northwest Uganda using allele-specific polymerase chain reaction
-
Nerima B, Matovu E, Lubega GW, Enyaru JC, (2007) Detection of mutant P2 adenosine transporter (TbAT1) gene in Trypanosoma brucei gambiense isolates from northwest Uganda using allele-specific polymerase chain reaction. Trop Med Int Health 12: 1361–1368.
-
(2007)
Trop Med Int Health
, vol.12
, pp. 1361-1368
-
-
Nerima, B.1
Matovu, E.2
Lubega, G.W.3
Enyaru, J.C.4
-
14
-
-
10744226397
-
Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei
-
Matovu E, Stewart ML, Geiser F, Brun R, Mäser P, et al. (2003) Mechanisms of arsenical and diamidine uptake and resistance in Trypanosoma brucei. Eukaryot Cell 2: 1003–1008.
-
(2003)
Eukaryot Cell
, vol.2
, pp. 1003-1008
-
-
Matovu, E.1
Stewart, M.L.2
Geiser, F.3
Brun, R.4
Mäser, P.5
-
15
-
-
0034852287
-
Genetic variants of the TbAT1 adenosine transporter from African trypanosomes in relapse infections following melarsoprol therapy
-
Matovu E, Geiser F, Schneider V, Mäser P, Enyaru JCK, et al. (2001) Genetic variants of the TbAT1 adenosine transporter from African trypanosomes in relapse infections following melarsoprol therapy. Mol Biochem Parasitol 117: 73–81.
-
(2001)
Mol Biochem Parasitol
, vol.117
, pp. 73-81
-
-
Matovu, E.1
Geiser, F.2
Schneider, V.3
Mäser, P.4
Enyaru, J.C.K.5
-
16
-
-
70449568251
-
Bioluminescent imaging of Trypanosoma brucei shows preferential testis dissemination which may hamper drug efficacy in sleeping sickness patients
-
Claes F, Vodnala SK, Van Reet N, Boucher N, Lunden-Miguel H, et al. (2009) Bioluminescent imaging of Trypanosoma brucei shows preferential testis dissemination which may hamper drug efficacy in sleeping sickness patients. PLoS Negl Trop Dis 3: e486.
-
(2009)
PLoS Negl Trop Dis
, vol.3
, pp. e486
-
-
Claes, F.1
Vodnala, S.K.2
Van Reet, N.3
Boucher, N.4
Lunden-Miguel, H.5
-
17
-
-
0037834651
-
A nucleoside transporter from Trypanosoma brucei involved in drug resistance
-
Mäser P, Sütterlin C, Kralli A, Kaminsky R, (1999) A nucleoside transporter from Trypanosoma brucei involved in drug resistance. Science 285: 242–244.
-
(1999)
Science
, vol.285
, pp. 242-244
-
-
Mäser, P.1
Sütterlin, C.2
Kralli, A.3
Kaminsky, R.4
-
18
-
-
33947354964
-
Loss of the high-affinity pentamidine transporter is responsible for high levels of cross-resistance between arsenical and diamine drugs in African trypanosomes
-
Bridges DJ, Gould MK, Nerima B, Mäser P, Burchmore RJS, et al. (2007) Loss of the high-affinity pentamidine transporter is responsible for high levels of cross-resistance between arsenical and diamine drugs in African trypanosomes. Mol Pharmacol 71: 1098–1106.
-
(2007)
Mol Pharmacol
, vol.71
, pp. 1098-1106
-
-
Bridges, D.J.1
Gould, M.K.2
Nerima, B.3
Mäser, P.4
Burchmore, R.J.S.5
-
19
-
-
84863585771
-
Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes
-
Baker N, Glover L, Munday JC, Aguinaga Andrés D, Barrett MP, et al. (2012) Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes. Proc Natl Acad Sci USA 109: 10996–11001.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 10996-11001
-
-
Baker, N.1
Glover, L.2
Munday, J.C.3
Aguinaga Andrés, D.4
Barrett, M.P.5
-
20
-
-
84887310584
-
Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates concur with decreased susceptibility to pentamidine and melarsoprol
-
Graf FE, Ludin P, Wenzler T, Kaiser M, Brun R, et al. (2013) Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates concur with decreased susceptibility to pentamidine and melarsoprol. PLoS Negl Trop Dis 7: e2475.
-
(2013)
PLoS Negl Trop Dis
, vol.7
, pp. e2475
-
-
Graf, F.E.1
Ludin, P.2
Wenzler, T.3
Kaiser, M.4
Brun, R.5
-
21
-
-
0026757141
-
The impact of human immunodeficiency virus infection on the epidemiology and treatment of Trypanosoma brucei gambiense sleeping sickness in Nioki, Zaire
-
Pépin J, Ethier L, Kazadi C, Milord F, Ryder R, (1992) The impact of human immunodeficiency virus infection on the epidemiology and treatment of Trypanosoma brucei gambiense sleeping sickness in Nioki, Zaire. Am J Trop Med Hyg 47: 133–140.
-
(1992)
Am J Trop Med Hyg
, vol.47
, pp. 133-140
-
-
Pépin, J.1
Ethier, L.2
Kazadi, C.3
Milord, F.4
Ryder, R.5
-
22
-
-
0242300051
-
Trypanosoma brucei gambiense African trypanosomiasis: differences between men and women in severity of disease and response to treatment
-
Pépin J, Mpia B, Iloasebe M, (2002) Trypanosoma brucei gambiense African trypanosomiasis: differences between men and women in severity of disease and response to treatment. Trans R Soc Trop Med Hyg 96: 421–426.
-
(2002)
Trans R Soc Trop Med Hyg
, vol.96
, pp. 421-426
-
-
Pépin, J.1
Mpia, B.2
Iloasebe, M.3
-
23
-
-
0032871338
-
Risk factors for treatment failure after melarsoprol for Trypanosoma brucei gambiense trypanosomiasis in Uganda
-
Legros D, Evans S, Maiso F, Enyaru JCK, Mbulamberi D, (1999) Risk factors for treatment failure after melarsoprol for Trypanosoma brucei gambiense trypanosomiasis in Uganda. Trans R Soc Trop Med Hyg 93: 439–442.
-
(1999)
Trans R Soc Trop Med Hyg
, vol.93
, pp. 439-442
-
-
Legros, D.1
Evans, S.2
Maiso, F.3
Enyaru, J.C.K.4
Mbulamberi, D.5
-
24
-
-
84894096486
-
Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs
-
Munday JC, Eze AA, Baker N, Glover L, Clucas C, et al. (2014) Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of resistance to these drugs. J Antimicrob Chemother 69: 651–663.
-
(2014)
J Antimicrob Chemother
, vol.69
, pp. 651-663
-
-
Munday, J.C.1
Eze, A.A.2
Baker, N.3
Glover, L.4
Clucas, C.5
-
25
-
-
79955847165
-
Isolation of Trypanosoma brucei gambiense from cured and relapsed sleeping sickness patients and adaptation to laboratory mice
-
Pyana PP, Ngay Lukusa I, Mumba Ngoyi D, Van Reet N, Kaiser M, et al. (2011) Isolation of Trypanosoma brucei gambiense from cured and relapsed sleeping sickness patients and adaptation to laboratory mice. PLoS Negl Trop Dis 5: e1025.
-
(2011)
PLoS Negl Trop Dis
, vol.5
, pp. e1025
-
-
Pyana, P.P.1
Ngay Lukusa, I.2
Mumba Ngoyi, D.3
Van Reet, N.4
Kaiser, M.5
-
26
-
-
84920510257
-
A panel of Trypanosoma brucei strains tagged with blue and red shifted luciferases for bioluminescent imaging in murine infection models
-
Van Reet N, Van de Vyver H, Pyana PP, Van der Linden AM, Büscher P, (2014) A panel of Trypanosoma brucei strains tagged with blue and red shifted luciferases for bioluminescent imaging in murine infection models. PLoS Negl Trop Dis In press.
-
(2014)
PLoS Negl Trop Dis
-
-
Van Reet, N.1
Van de Vyver, H.2
Pyana, P.P.3
Van der Linden, A.M.4
Büscher, P.5
-
27
-
-
73449124061
-
Improved models of mini anion exchange centrifugation technique (mAECT) and modified single centrifugation (MSC) for sleeping sickness diagnosis and staging
-
Büscher P, Mumba Ngoyi D, Kaboré J, Lejon V, Robays J, et al. (2009) Improved models of mini anion exchange centrifugation technique (mAECT) and modified single centrifugation (MSC) for sleeping sickness diagnosis and staging. PLoS Negl Trop Dis 3: e471.
-
(2009)
PLoS Negl Trop Dis
, vol.3
, pp. e471
-
-
Büscher, P.1
Mumba Ngoyi, D.2
Kaboré, J.3
Lejon, V.4
Robays, J.5
-
28
-
-
0014884946
-
Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose
-
Lanham SM, Godfrey DG, (1970) Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose. Exp Parasitol 28: 521–534.
-
(1970)
Exp Parasitol
, vol.28
, pp. 521-534
-
-
Lanham, S.M.1
Godfrey, D.G.2
-
29
-
-
0027969338
-
Gene expression mediated by bacteriophage T3 and T7 RNA polymerase in transgenic trypanosomes
-
Wirtz E, Hartmann C, Clayton C, (1994) Gene expression mediated by bacteriophage T3 and T7 RNA polymerase in transgenic trypanosomes. Nucleic Acids Res 22: 3887–3894.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 3887-3894
-
-
Wirtz, E.1
Hartmann, C.2
Clayton, C.3
-
30
-
-
33644982177
-
Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania
-
Kibona SN, Matemba L, Kaboya JS, Lubega GW, (2006) Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania. Trop Med Int Health 11: 144–155.
-
(2006)
Trop Med Int Health
, vol.11
, pp. 144-155
-
-
Kibona, S.N.1
Matemba, L.2
Kaboya, J.S.3
Lubega, G.W.4
-
31
-
-
70449504710
-
Murine models for Trypanosoma brucei gambiense disease progression-from silent to chronic infections and early brain tropism
-
Giroud C, Ottones F, Coustou V, Dacheux D, Biteau N, et al. (2009) Murine models for Trypanosoma brucei gambiense disease progression-from silent to chronic infections and early brain tropism. PLoS Negl Trop Dis 3: e509.
-
(2009)
PLoS Negl Trop Dis
, vol.3
, pp. e509
-
-
Giroud, C.1
Ottones, F.2
Coustou, V.3
Dacheux, D.4
Biteau, N.5
-
32
-
-
0015182569
-
Historique de la lutte contre la maladie du sommeil au Congo
-
Burke J, (1971) Historique de la lutte contre la maladie du sommeil au Congo. Ann Soc Belg Méd Trop 51: 465–477.
-
(1971)
Ann Soc Belg Méd Trop
, vol.51
, pp. 465-477
-
-
Burke, J.1
-
33
-
-
0034740633
-
Trypanosomiase humaine africaine: historique de la thérapeutique et ses échecs
-
Ollivier G, Legros D, (2001) Trypanosomiase humaine africaine: historique de la thérapeutique et ses échecs. Trop Med Int Health 6: 11–855.
-
(2001)
Trop Med Int Health
, vol.6
, pp. 11-855
-
-
Ollivier, G.1
Legros, D.2
-
34
-
-
20444410350
-
Trypanosoma brucei s.l.: Characterisation of stocks from Central Africa by PCR analysis of mobile genetic elements
-
Simo G, Herder S, Nijokou F, Asonganyi T, Tilley A, et al. (2005) Trypanosoma brucei s.l.: Characterisation of stocks from Central Africa by PCR analysis of mobile genetic elements. Exp Parasitol 110: 353–362.
-
(2005)
Exp Parasitol
, vol.110
, pp. 353-362
-
-
Simo, G.1
Herder, S.2
Nijokou, F.3
Asonganyi, T.4
Tilley, A.5
-
35
-
-
46249092625
-
Novel markers for treatment outcome in late stage T.b. gambiense trypanosomiasis
-
Lejon V, Roger M, Mumba Ngoyi D, Menten J, Robays J, et al. (2008) Novel markers for treatment outcome in late stage T.b. gambiense trypanosomiasis. Clin Infect Dis 47: 15–22.
-
(2008)
Clin Infect Dis
, vol.47
, pp. 15-22
-
-
Lejon, V.1
Roger, M.2
Mumba Ngoyi, D.3
Menten, J.4
Robays, J.5
-
36
-
-
4444384506
-
Efficacy of 10-day melarsoprol schedule 2 years after treatment for late-stage gambiense sleeping sickness
-
Schmid C, Nkunku S, Merolle A, Vounatsou P, Burri C, (2004) Efficacy of 10-day melarsoprol schedule 2 years after treatment for late-stage gambiense sleeping sickness. Lancet 364: 789–790.
-
(2004)
Lancet
, vol.364
, pp. 789-790
-
-
Schmid, C.1
Nkunku, S.2
Merolle, A.3
Vounatsou, P.4
Burri, C.5
-
37
-
-
33750251243
-
Treatment outcomes and risk factors for relapse in patients with early-stage human African trypanosomiasis (HAT) in the Republic of the Congo
-
Balasegaram M, Harris S, Checchi F, Hamel C, Karunakara U, (2006) Treatment outcomes and risk factors for relapse in patients with early-stage human African trypanosomiasis (HAT) in the Republic of the Congo. Bull World Health Organ 84: 777–782.
-
(2006)
Bull World Health Organ
, vol.84
, pp. 777-782
-
-
Balasegaram, M.1
Harris, S.2
Checchi, F.3
Hamel, C.4
Karunakara, U.5
|