Genotypic and phenotypic characterization of Trypanosoma brucei gambiense isolates from Ibba, South Sudan, an area of high melarsoprol treatment failure rate

Acta Tropica

Volumn 104, Issue 2-3, 2007, Pages 84-90

  Maina, Naomi ^a,c   Maina, Kagira Joseph ^a   Mäser, Pascal ^b   Brun, Reto ^c  

^a Trypanosomiasis Research Institute (TRC)   (Kenya)

^b UNIVERSITY OF BERN   (Switzerland)

^c SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

Drug sensitivity; Melarsoprol; Sudan; T. b. gambiense; TbAT1 gene

Indexed keywords

DIMINAZENE; MELARSENOXIDE; MELARSOPROL;

ALLELE; DISEASE TREATMENT; DRUG; DRUG RESISTANCE; FLAGELLATE; GENE EXPRESSION; GENOTYPE; MUTATION; PHENOTYPE; POLYMERASE CHAIN REACTION;

AFRICAN TRYPANOSOMIASIS; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CONTROLLED STUDY; DRUG RESISTANCE; DRUG UPTAKE; GENE SEQUENCE; IN VITRO STUDY; INCIDENCE; MOUSE; NONHUMAN; POINT MUTATION; POLYMERASE CHAIN REACTION; SUDAN; TREATMENT FAILURE; TRYPANOSOMA;

ANIMALS; ARSENICALS; DIMINAZENE; DRUG RESISTANCE; GENOTYPE; MELARSOPROL; MICE; NIFURTIMOX; NUCLEOSIDE TRANSPORT PROTEINS; PARASITIC SENSITIVITY TESTS; PENTAMIDINE; PHENOTYPE; POLYMERASE CHAIN REACTION; SUDAN; TREATMENT FAILURE; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI GAMBIENSE; TRYPANOSOMIASIS, AFRICAN;

AFRICA; AL-ISTIWAI; EAST AFRICA; IBBA; SUB-SAHARAN AFRICA; SUDAN;

MUS; TRYPANOSOMA BRUCEI GAMBIENSE;

EID: 35348915954     PISSN: 0001706X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actatropica.2007.07.007     Document Type: Article

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