Novel isotopic N,N-Dimethyl Leucine (iDiLeu) reagents enable absolute quantification of peptides and proteins using a standard curve approach

Journal of the American Society for Mass Spectrometry

Volumn 26, Issue 1, 2014, Pages 107-119

  Greer, Tyler ^a   Lietz, Christopher B ^a   Xiang, Feng ^a   Li, Lingjun ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Absolute quantification; DiLeu; Dimethylated amino acid; iDiLeu; Isotopic labeling; Protein peptide quantification; Standard curve

Indexed keywords

AMINO ACIDS; CHEMICAL MODIFICATION; COST EFFECTIVENESS; ISOTOPES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

ABSOLUTE QUANTIFICATION; COLLISIONAL DISSOCIATION; DILEU; IDILEU; ISOTOPIC LABELING; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MULTIPLE REACTION MONITORING; QUANTIFICATION METHODS;

PEPTIDES;

ALLATOSTATIN; AMINE; ISOTOPIC N,N DIMETHYL LEUCINE; LEUCINE; PEPTIDES AND PROTEINS; REAGENT; TRIAZINE DERIVATIVE; TRYPSIN; UNCLASSIFIED DRUG; ALLATOSTATIN 1; INSECT HORMONE; PEPTIDE; PROTEIN; PROTEOME;

ACCURACY; ARTICLE; CHEMICAL LABELING; DISSOCIATION; MOUSE; NONHUMAN; PROTEIN ANALYSIS; AMINO ACID SEQUENCE; ANIMAL; CALIBRATION; CHEMICAL MODEL; CHEMISTRY; MASS SPECTROMETRY; METHYLATION; PROCEDURES; PROTEOMICS; STANDARDS; STATISTICAL MODEL; URINE;

AMINO ACID SEQUENCE; ANIMALS; CALIBRATION; INSECT HORMONES; LEUCINE; LINEAR MODELS; MASS SPECTROMETRY; METHYLATION; MICE; MODELS, CHEMICAL; PEPTIDES; PROTEINS; PROTEOME; PROTEOMICS;

EID: 84919952212     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-014-1012-y     Document Type: Article

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