The development of an industrial-scale fed-batch fermentation simulation

Journal of Biotechnology

Volumn 193, Issue , 2015, Pages 70-82

  Goldrick, Stephen ^a,b,c   Ştefan, Andrei ^b   Lovett, David ^c   Montague, Gary ^a,d   Lennox, Barry ^b  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c PERCEPTIVE ENGINEERING LTD   (United Kingdom)

^d TEESSIDE UNIVERSITY   (United Kingdom)

Author keywords

Industrial fermentation; Kinetic modelling; Penicillin production; Simulation; Structured model

Indexed keywords

CARBON DIOXIDE; DISSOLVED OXYGEN; FERMENTATION; SIMULATORS; SOCIAL NETWORKING (ONLINE); SYSTEMS ANALYSIS;

INDUSTRIAL FERMENTATION; KINETIC MODELLING; PENICILLIN PRODUCTION; SIMULATION; STRUCTURED MODEL;

PROCESS CONTROL;

CARBON DIOXIDE; DISSOLVED OXYGEN; NITROGEN; PENICILLIN DERIVATIVE; OXYGEN;

ARTICLE; BIOMASS; BIOREACTOR; BIOTECHNOLOGY; CONTROL STRATEGY; DRUG INDUSTRY; FED BATCH FERMENTATION; FUNGAL STRAIN; GAS ANALYSIS; HYDROLYSIS; MEASUREMENT; PENICILLIUM CHRYSOGENUM; PH; SIMULATION; SIMULATOR; TEMPERATURE; VISCOSITY; BATCH CELL CULTURE; BIOLOGICAL MODEL; COMPUTER SIMULATION; DEVICES; FERMENTATION; KINETICS; METABOLISM; MICROBIOLOGY; PROCEDURES;

PENICILLIUM CHRYSOGENUM;

BATCH CELL CULTURE TECHNIQUES; BIOMASS; BIOREACTORS; COMPUTER SIMULATION; FERMENTATION; INDUSTRIAL MICROBIOLOGY; KINETICS; MODELS, BIOLOGICAL; OXYGEN; PENICILLINS; PENICILLIUM CHRYSOGENUM;

EID: 84919935414     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2014.10.029     Document Type: Article

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